Navigation Links
Major clinical trial finds no link between genetic risk factors and 2 top wet AMD treatments
Date:2/12/2013

ent, which were improvement or loss of visual acuity, the status of the retinal anatomy, and the number of medication injections given.

"Our genetic research team remains hopeful that gene variants that predict patient response to AMD treatments will be identified soon," said Dr. Hagstrom. "This would enable a significant leap forward in ophthalmologists' ability to individualize treatment and care plans for their patients."

The main CATT study was a multi-center clinical trial that was funded by the National Institutes of Health and led by Daniel F. Martin, M.D., Chairman of the Cole Eye Institute at the Cleveland Clinic. The study compared Lucentis and Avastin for effectiveness and safety in treating the wet form of AMD.

The findings of the CATT genetic study lend further weight to the American Academy of Ophthalmology's 2012 recommendation on the use of genetic testing . This study assessed the same four major gene variants that are most widely used in current AMD genetic tests and found that the treatment response in patients who carried the gene variants was no better or worse than in patients who did not. The Academy advises against routine genetic testing for AMD and other complex eye disorders until specific treatment or monitoring strategies have been shown in clinical trials to be of benefit to people with specific, risk-linked genotypes.

Wet AMD, also called neovascular AMD, can severely damage vision if not treated in time. About 10 percent of patients suffer from the wet form, in which abnormal blood vessels grow underneath the retina, the tissue at the back of the eye that is crucial to good vision. These vessels leak fluid or blood, which blurs or distorts the central vision that enables people to read, recognize faces, drive, and perform other daily activities. Scientists now think that about half of all cases of AMD are related to specific genes.


'/>"/>

Contact: Mary Wade
mwade@aao.org
415-447-0221
American Academy of Ophthalmology
Source:Eurekalert

Page: 1 2

Related biology news :

1. Global Companion Diagnostic Market Worth $19.3 billion by 2023: What it Takes to Become a Major Companion Diagnostic Player
2. Genetics plays major role in victimization in elementary school
3. Major cuts to surging CO2 emissions are needed now, not down the road, study finds
4. Majority of Americans doubt Congress and White House can avoid fiscal cliff
5. Mercury releases contaminate ocean fish: Dartmouth-led effort publishes major findings
6. Major breakthrough in deciphering bread wheats genetic code
7. Major international push to maximize bioscience research to help worlds poorest farmers
8. Baylor University scientist receives major grants for health research on 1991 Gulf War veterans
9. British Library leads the way for sharing data as major institutions sign up to DataCite
10. Whitehead scientists identify major flaw in standard approach to global gene expression analysis
11. Major changes needed to protect Australias species and ecosystems
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/17/2014)... Clemson professor Rajendra Singh Thursday as a "Champion ... expand solar deployment in the residential, commercial and ... Professor of Electrical and Computer Engineering and director ... a local hero leading the charge across the ... solar power and driving policy changes at the ...
(Date:4/17/2014)... devastate honeybees in Europe, Asia and the United States ... to be impacting native honeybee populations at this time, ... pests include including Nosema microsporidia and ... be resilient to these invasive pests, which suggests to ... Europe, Asia and the United States currently are not ...
(Date:4/17/2014)... France have hit on a novel method to ... correct and most effective treatment possible., Kidney stones ... and developing world. If left untreated, apart from ... failure and other complications. In many patients treated ... a more effective pathological approach to diagnosis and ...
Breaking Biology News(10 mins):White House honors Clemson professor as 'Champion of Change' for solar deployment 2East African honeybees are safe from invasive pests… for now 2East African honeybees are safe from invasive pests… for now 3
... Manchester have successfully extracted protein from the bones of ... the identification of ancient fossils. Using an ultra-high ... near complete collagen sequence for the West Runton Elephant, ... in Norfolk in 1990. The remarkable 85 per cent ...
... new series of events at the New York Academy ... that may offer large cities sustainable alternatives to landfill ... "Trash Talk" series on Thursday, April 7, will examine ... treatment. Experts will explain how these technologies ...
... pollutants whose lack of solubility in water, or "hydrophobicity," has ... Aviv University research has discovered that this is indeed the ... University,s School of Chemistry at the Raymond and Beverly Sackler ... TAU,s Laboratory of Nanomedicine in the Department of Cell Research ...
Cached Biology News:West Runton Elephant helps unlock the past 2Mucus: Fighting the war against pollutants 2
(Date:1/15/2014)... Ill. , Jan. 15, 2014  Bill Jacobs Automotive, a ... , is teaming up with the Heartland Blood Center and ... blood drive. The drive takes place Saturday, Jan. 18 at ... - 2 p.m. (Photo: http://photos.prnewswire.com/prnh/20140115/MN46637 )  ...
(Date:1/15/2014)... Cynvenio, a cancer diagnostics company focused on ... of tumor cells in the bloodstream, today announced that ... support application powered by CollabRx, Inc. , Available ... Therapy Finder will provide breast cancer patients and their ...
(Date:1/15/2014)... A study has been launched to test ... track could help to tackle the problem of obesity.  This ... GP surgery based in Stowmarket) and academics at University Campus ... Telemetry technology, which is inspired by equipment used to collect ...
(Date:1/15/2014)... 2014 DTS Language Services, Inc . ... Portal for Life Science organizations who need document translations. ... matter of their documents in advance with a selection of ... of translations, often a critical factor in clinical and scientific ...
Breaking Biology Technology:Join the Bill Jacobs Auto blood drive and receive a free oil change 2Cynvenio Offers New Breast Cancer Therapy Finder Application for its ClearID Breast Cancer Genomic Test 2Cynvenio Offers New Breast Cancer Therapy Finder Application for its ClearID Breast Cancer Genomic Test 3Formula 1 Technology Tackles Obesity in Unique Healthcare Partnership 2Formula 1 Technology Tackles Obesity in Unique Healthcare Partnership 3Formula 1 Technology Tackles Obesity in Unique Healthcare Partnership 4DTS Improves Efficiency for Life Science Document Translations 2
... the College,s history, BRONX, N.Y., May 13 ... University today announced that it has received a ... largest in the College,s 53-year history,-- from Ruth ... the Gottesmans is,available., (Photo: http://www.newscom.com/cgi-bin/prnh/20080513/NYTU059-a ), ...
... Milestone, NEW YORK, May 13 NeoStem, Inc. ... processing and long-term,storage of adult stem cells for future ... for a new stem cell collection center in Coral,Gables, ... MBA, NeoStem,s Chairman and Chief Executive Officer,commented: "Securing the ...
... Pacific Time, SAN DIEGO, May 13 SGX ... for the first quarter,of 2008. For the three months ... $17.0 million and net income of $3.7 million. The ... that was,attributable to the one-time recognition of the remaining ...
Cached Biology Technology:Albert Einstein College of Medicine Receives $25-Million Gift to Support Stem Cell and Epigenomic Research and Clinical Skills Training 2Albert Einstein College of Medicine Receives $25-Million Gift to Support Stem Cell and Epigenomic Research and Clinical Skills Training 3Albert Einstein College of Medicine Receives $25-Million Gift to Support Stem Cell and Epigenomic Research and Clinical Skills Training 4Albert Einstein College of Medicine Receives $25-Million Gift to Support Stem Cell and Epigenomic Research and Clinical Skills Training 5NeoStem to Expand Stem Cell Collection Center Network to Florida 2NeoStem to Expand Stem Cell Collection Center Network to Florida 3SGX Pharmaceuticals Announces First Quarter Financial Results and Gives Pipeline Update 2SGX Pharmaceuticals Announces First Quarter Financial Results and Gives Pipeline Update 3SGX Pharmaceuticals Announces First Quarter Financial Results and Gives Pipeline Update 4SGX Pharmaceuticals Announces First Quarter Financial Results and Gives Pipeline Update 5SGX Pharmaceuticals Announces First Quarter Financial Results and Gives Pipeline Update 6SGX Pharmaceuticals Announces First Quarter Financial Results and Gives Pipeline Update 7SGX Pharmaceuticals Announces First Quarter Financial Results and Gives Pipeline Update 8
For testing the AQUA technique on your MS instruments....
Our original highly-purified, robust Taq Polymerase which delivers consistently high yields and minimal background...
A formulation of our Biolase DNA Polymerase which contains a Red Loading Dye...
... enzyme-linked immunosorbent assay (ELISA) test kits ... devices for the detection of drugs and/or ... are intended for forensic use only. It ... confirmed by a quantitative method such as ...
Biology Products: