Navigation Links
'Mahjong' gene is key player when cancer, normal cells compete
Date:7/13/2010

"When tetracycline was added to the tissue, the cells in which Mahjong had been shut down began to die, just as they had in the fruit fly," Tamori said.

"In the kidney cells, as in flies," he said, "apoptosis was only observed in Mahjong mutants when they were surrounded by normal cells. We now had a clear demonstration of cell competition in mammalian tissue, triggered by mutations in a key protein."

Next, the team sought to prevent apoptosis in cells that lacked Lgl or Mahjong by copying the remaining protein partner in larger-than-normal numbers.

"We learned that overexpressing Mahjong in Lgl-deficient cells, which typically self destruct, did in fact prevent apoptosis," Deng said. "But, in contrast, we found that overexpressing Lgl in Mahjong-deficient cells did not prevent cell suicide."


'/>"/>

Contact: Yoichiro Tamori
yotamori@bio.fsu.edu
850-645-1502
Florida State University
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Vitamin D a key player in overall health of several body organs, says UC Riverside biochemist
2. Frost & Sullivan Recognizes Precise Biometrics as a Key Player in the Non-AFIS Fingerprint Market
3. New estrogen receptor found to be key player in tamoxifen resistance
4. New study finds lowfat chocolate milk is effective post-exercise recovery aid for soccer players
5. Little-known protein found to be key player
6. Key player found for a cancer typical in Down syndrome
7. La Jolla Institute scientist leads team which discovers important new player in diabetes onset
8. Amid the murk of gut flora, vitamin D receptor emerges as a key player
9. In lung cancer, silencing one crucial gene disrupts normal functioning of genome
10. UT Southwestern researchers disrupt biochemical system involved in cancer, degenerative disease
11. Research yields potential target for cancer, wound healing and fibrosis
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
'Mahjong' gene is key player when cancer, normal cells compete
(Date:3/24/2015)... PALM BEACH GARDENS, Fla. , March 24, ... of biometric identity management solutions, today announced that ... enabling premium clothing accessory retailer Goorin Bros ... login. The Crossmatch biometrics-based solution secures access to ... customers from the increased risk of data breaches. ...
(Date:3/20/2015)... , Mar. 20, 2015 Research and Markets ... addition of the "India Sensors Market Forecast ... The sensor market is projected to ... Consumer electronics, automotive, industrial and healthcare ... in the country. In addition, adoption of MEMS ...
(Date:3/18/2015)... -- As mobile payments become more prevalent amongst ... apps continue to be introduced into the market place at ... industry in focus today are:  NXT-ID, Inc. (NASDAQ: ... ), Apple Inc. (NASDAQ: AAPL ), Google Inc. ... FB ) NXT-ID, Inc. (NASDAQ: ...
Breaking Biology News(10 mins):Crossmatch Fingerprint Readers Help Retailer Prevent Data Breaches at Point-of-Sale 2India Sensors Market Forecast and Opportunities 2020 - STMicroelectronics held the largest share in 2014 2India Sensors Market Forecast and Opportunities 2020 - STMicroelectronics held the largest share in 2014 3Revolutionary Smart Wallet & Mobile Payment Choices Change the Game for Consumers - Company Begins Shipping Newest Digital Wallet to Customers 2Revolutionary Smart Wallet & Mobile Payment Choices Change the Game for Consumers - Company Begins Shipping Newest Digital Wallet to Customers 3Revolutionary Smart Wallet & Mobile Payment Choices Change the Game for Consumers - Company Begins Shipping Newest Digital Wallet to Customers 4Revolutionary Smart Wallet & Mobile Payment Choices Change the Game for Consumers - Company Begins Shipping Newest Digital Wallet to Customers 5Revolutionary Smart Wallet & Mobile Payment Choices Change the Game for Consumers - Company Begins Shipping Newest Digital Wallet to Customers 6
... populations of rainbow trout -- one in Alaska, the other ... huge implications for fisheries conservation and management, an eight-member research ... rate of development that has allowed these different salmomid subspecies ... The researchers, in a paper put online ahead of publication ...
... Worcester Polytechnic Institute (WPI) and CellThera, a private company ... regenerated functional muscle tissue in mice, opening the door ... suffer major muscle trauma. The team used a ... a stem cell-like state and grew those reprogrammed cells ...
... surface of an implant such as a new hip or ... and researchers at the University of Gothenburg, Sweden, can now ... are presented in the International Journal of Nanomedicine . ... of the most common reasons for an implant being rejected," ...
Cached Biology News:Genetic buzzer-beater genes may save fish 2Genetic buzzer-beater genes may save fish 3Body rebuilding: Researchers regenerate muscle in mice 2Body rebuilding: Researchers regenerate muscle in mice 3Cobblestones fool innate immunity 2
(Date:4/23/2015)... (PRWEB) April 23, 2015 Athena San ... development of executive women in San Diego’s technology and ... 17th Annual Pinnacle Awards at their Gala on April ... Hotel. Register now at http://athenasd.org/events/ , The ... the Athena San Diego vision of fostering networking, risk ...
(Date:4/23/2015)... , April 23, 2015 BioTE Medical President ... book "Age Healthier Live Happier - Avoiding Over-Medication through ... Age Management Medicine Group Conference at JW Marriott / ... ",Age Healthier Live Happier, is a welcomed ... over-medication and searching for a higher quality of life ...
(Date:4/23/2015)... -- WuXi PharmaTech (Cayman) Inc. (NYSE: WX ), ... serving the pharmaceutical, biotechnology and medical device industries, with ... the United States , today announced that ... of 2015 after the New York Stock Exchange closes ... morning, May 14, 2015 Shanghai time). The earnings release ...
(Date:4/23/2015)... SAN FRANCISCO, Calif. , April 23, 2015  Veracyte, ... has entered into a definitive agreement to sell approximately ... placement. Under the agreement, the investors will purchase an ... purchase price of $8.15 per share, the closing stock ... led by new and existing investors, including Broadfin Capital, ...
Breaking Biology Technology:Athena Pinnacle Awards to Honor Executives, Corporations and Educators Working to Promote Women Leaders 2Release and Book Signing of BioTE Medical President Gary Donovitz M.D. 'Age Healthier Live Happier' at Age Management Medicine Group (AMMG) Conference 2Release and Book Signing of BioTE Medical President Gary Donovitz M.D. 'Age Healthier Live Happier' at Age Management Medicine Group (AMMG) Conference 3WuXi PharmaTech Schedules First-Quarter 2015 Earnings Release 2WuXi PharmaTech Schedules First-Quarter 2015 Earnings Release 3Veracyte, Inc. Announces $40 Million Private Placement 2Veracyte, Inc. Announces $40 Million Private Placement 3Veracyte, Inc. Announces $40 Million Private Placement 4
... are creating interesting new sounds, sites, and uses. In ... one song with the words of another, generating an ... ,On the web, mashups are created through the combination ... or other content linked with other data elements to ...
... - What do venture coaching, the "Elevator Pitch Olympics," and ... components of the second annual Wisconsin Early Stage Symposium, which ... 31, at Monona Terrace Convention Center. The symposium is co-produced ... non-profit science and technology adviser to state government. , ,The ...
... ilwaukee, Wis. - Ten years from now, when ... with color and clarity, they probably won't think much about ... But they are hard at work as movie-goers take in ... makers aren't all situated in Hollywood. One of them is ...
Cached Biology Technology:Would you like your music (and data) mashed? 2Would you like your music (and data) mashed? 3Would you like your music (and data) mashed? 4Would you like your music (and data) mashed? 5Symposium will include venture capital "coaching" 2CIO Leadership Series: Jane Durment, Marcus Corp. 2CIO Leadership Series: Jane Durment, Marcus Corp. 3CIO Leadership Series: Jane Durment, Marcus Corp. 4
...
Ezrin/Radixin/Moesin Antibody...
Smac/DIABLO (mouse) (CT) rabbit polyclonal antibody...
... ADAMTS16 ( Abpromise for all ... Synthetic peptide based on the ... the amino acid sequence is proprietary) ... 170690 SWISS Protein ...
Biology Products: