Navigation Links
Magnetically controlled pill could boost body's absorption of drugs
Date:1/17/2011

Do you want that in a pill or a shot? A pill, thank you, but most patients never have that choice. The problem with administering many medications orally is that a pill often will not dissolve at exactly the right site in the gastrointestinal tract where the medicine can be absorbed into the bloodstream. A new magnetic pill system developed by Brown University researchers could solve the problem by safely holding a pill in place in the intestine wherever it needs to be.

The scientists describe the harmless operation of their magnetic pill system in rats online the week of Jan. 17 in the Proceedings of the National Academy of Sciences. Applied to people in the future, said senior author Edith Mathiowitz, the technology could provide a new way to deliver many drugs to patients, including those with cancer or diabetes. It could also act as a powerful research tool to help scientists understand exactly where in the intestine different drugs are best absorbed.

"With this technology you can now tell where the pill is placed, take some blood samples and know exactly if the pill being in this region really enhances the bioavailability of the medicine in the body," said Mathiowitz, professor of medical science in Brown's Department of Molecular Pharmacology, Physiology, and Biotechnology. "It's a completely new way to design a drug delivery system."

The two main components of the system are conventional-looking gelatin capsules that contain a tiny magnet, and an external magnet that can precisely sense the force between it and the pill and vary that force, as needed, to hold the pill in place. The external magnet can sense the pill's position, but because the pill is opaque to x-rays, the researchers were also able to see the pill in the rat's bodies during their studies.

Safety first

The system is not the first attempt to guide pills magnetically, but it is the first one in which scientists can control the forc
'/>"/>

Contact: David Orenstein
David_Orenstein@brown.edu
401-863-1862
Brown University
Source:Eurekalert

Page: 1 2

Related biology news :

1. Texas Childrens Cancer Center first in Texas to magnetically lengthen nine-year-olds leg as she grows
2. Can genetic information be controlled by light?
3. Motor nerve targeting to limb muscles is controlled by ephrin proteins
4. Vitamins C and E and beta carotene again fail to reduce cancer risk in randomized controlled trial
5. Major international study challenges notions of how genes are controlled in mammals
6. Study may aid efforts to prevent uncontrolled cell division in cancer
7. Step forward for nanotechnology: Controlled movement of molecules
8. Researchers design a tool to induce controlled suicide in human cells
9. Brain-controlled cursor doubles as a neural workout
10. Health Robotics i.v.STATION Certified as the Only Robot to Comply with Security Guidelines for Controlled Substances
11. Discovery of controlled swarm in bacteria
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/20/2015)... , April 20, 2015 Huntington Memorial ... Valley to implant a new miniaturized, wireless monitoring sensor ... is the first and only FDA-approved heart failure monitoring ... admissions when used by physicians to manage heart failure. ... that is implanted in the pulmonary artery (PA) during ...
(Date:4/13/2015)... 2015 According to a ... Market Forecast & Opportunities, 2020", the global biometrics market ... 14% till 2020. The biometrics market is garnering ... and review of biometric management systems. The constant ... with greater efficiency, are resulting in increasing installation ...
(Date:4/6/2015)... 6, 2015 NXT-ID, Inc. (NASDAQ: NXTD ... company focused on the growing mobile commerce market, ... 62/143028 for MINIATURE, MULTI-PURPOSE ANTENNA METHOD AND ... NXT-ID introduces a new revolutionary method and ... the use of miniature antenna modules for multiple ...
Breaking Biology News(10 mins):Huntington Memorial Hospital Becomes First in the San Gabriel Valley to Offer Patients a New Heart Failure Monitoring Solution 2Huntington Memorial Hospital Becomes First in the San Gabriel Valley to Offer Patients a New Heart Failure Monitoring Solution 3Global Biometrics Market to Cross US$ 21 Billion by 2020: TechSci Research 2NXT-ID Patents Miniature, Low Power Wireless Magnetic Stripe 2NXT-ID Patents Miniature, Low Power Wireless Magnetic Stripe 3NXT-ID Patents Miniature, Low Power Wireless Magnetic Stripe 4
... due to predators, particularly in fragmented forest areas, but why? ... predator to find an answer. , "Rat snakes ... said U of I researcher Patrick Weatherhead. "Our hypothesis ... the edges of the forest, that,s where bird nests should ...
... being spewed into the Gulf of Mexico from the Deepwater ... the leak. However, in the cleanup efforts to come, "extreme ... bad situation even worse, says a leading bioremediation expert with ... of detergents and other chemicals used to clean up sites ...
... the University of Granada (UGR) have studied the natural history ... of Polygala balansae in Europe, a thorny bush ... previously thought to be exclusive to Morocco. The team of ... on the list of threatened species. In 2006, a ...
Cached Biology News:Fragmented forests result in more snakes, fewer birds 2Fragmented forests result in more snakes, fewer birds 3Caution required for Gulf oil spill clean-up 2Polygala balansae, a new bush to Europe, at risk of extinction in Spain 2
(Date:4/23/2015)... The Thomas Brain Health Center ... groundbreaking pilot study to see if early Alzheimer’s ... little as three to six months. , The ... medicine—will aggressively target and simultaneously treat the numerous ... brain. These include oxidative stress, neuroinflammation, mitochondrial dysfunction, ...
(Date:4/23/2015)... 23, 2015 WuXi PharmaTech (Cayman) Inc. (NYSE: ... technology platform company serving the pharmaceutical, biotechnology and medical ... and the United States , ... the first quarter of 2015 after the New York ... will be Thursday morning, May 14, 2015 Shanghai time). ...
(Date:4/23/2015)... 2015 Glemser Technologies ... EMC® Enterprise Content Division (ECD) Certified Solution Partner ... Documentum® for Life Sciences Solution Suite . The ... capabilities to provide life sciences companies of all ... The EMC Documentum Solution Suite offers four modules: ...
(Date:4/23/2015)... 23, 2015 ReliantHeart's HeartAssist5® Ventricular Assist ... flow through the device) in real time, and this ... world’s leading provider of Machine to Machine (M2M) communications ... Flow via VADLink.com can be monitored by ... drop in flow below a minimum threshold, the patient ...
Breaking Biology Technology:New Study Looks to Reverse Alzheimer’s Disease 2New Study Looks to Reverse Alzheimer’s Disease 3WuXi PharmaTech Schedules First-Quarter 2015 Earnings Release 2WuXi PharmaTech Schedules First-Quarter 2015 Earnings Release 3Glemser Earns Accreditation for Life Sciences Solution Suite 2
... Outside the convention hall, I stopped last week to ... poor farmers poorer. He was a young and pleasant enough ... ,I told him biotechnology may be the last, best hope ... of millions of people who dont get enough to eat ...
... eFilm , a Wisconsin-based health care imaging software ... FUSION PACS version 1.2.7. The new version ... image viewer plug-in and automated access to DICOM ... medical record makes provision of appropriate images and ...
... service it claims will eliminate the hassles of in-house corporate ... or orders, companies can buy fax or mail services on ... the case of faxes, phone systems. , ,We see customers ... order to save money and IT resources, and only pay ...
Cached Biology Technology:The New Green Revolution offers hope to poor farmers and poor consumers 2The New Green Revolution offers hope to poor farmers and poor consumers 3
...
Smac/DIABLO (CT) - IgG for Western Blotting, Host: Rabbit Family: Smac/DIABLO...
Mouse monoclonal [ICRF 44] to Integrin alpha M...
... The new Finnpipette Focus ... tip cone for pipetting from ... other narrow and long necked ... that whatever volume you select, ...
Biology Products: