Navigation Links
Magnetic nano-'shepherds' organize cells
Date:3/31/2009

DURHAM, N.C. -- The power of magnetism may address a major problem facing bioengineers as they try to create new tissue -- getting human cells to not only form structures, but to stimulate the growth of blood vessels to nourish that growth.

A multidisciplinary team of investigators from Duke University, Case Western Reserve University and the University of Massachusetts, Amherst created an environment where magnetic particles suspended within a specialized solution act like molecular sheep dogs. In response to external magnetic fields, the shepherds nudge free-floating human cells to form chains which could potentially be integrated into approaches for creating human tissues and organs.

The cells not only naturally adhere to each other upon contact, the researchers said, but the aligned cellular configurations may promote or accelerate the creation and growth of tiny blood vessels.

"We have developed an exciting way of using magnetism to manipulate human cells floating freely in a solution containing magnetic nanoparticles" said Randall Erb, fourth-year graduate student in the laboratory of Benjamin Yellen, assistant professor of Mechanical Engineering and Materials Science, at Duke University's Pratt School of Engineering. "This new cell assembly process holds much promise for tissue engineering research and offers a novel way to organize cells in an inexpensive, easily accessible way."

Melissa Krebs, third-year biomedical engineering graduate student at Case Western and Erb's sister, co-authored a paper appearing online in advance of the May publication of Nano Letters, a journal published by the American Chemical Society.

"The cells have receptors on their surfaces that have an affinity for other cells," Krebs said. "They become sticky and attach to each other. When endothelial cells get together in a linear fashion, as they did in our experiments, it may help them to organize into tiny tubules."

T
'/>"/>

Contact: Richard Merritt
richard.merritt@duke.edu
919-660-8414
Duke University
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Magnetic snakes control fluids, gravity-defying droplets, and solving a dragonfly mystery
2. Do migratory birds see the magnetic field?
3. New magnetic separation technique might detect multiple pathogens at once
4. New system would use rotating magnetic field to detect pathogens
5. UVa biomedical engineering study shows magnetic field can reduce swelling
6. Biomagnetics developed for use in new breast cancer tests
7. Researchers mimic bacteria to produce magnetic nanoparticles
8. Caltech geobiologists discover unique magnetic death star fossil
9. Electromagnetic phantom exorcises specters of metal detector tests
10. Magnetic nanoparticles navigate therapeutic genes through the body
11. Changing environment organizes genetic structure
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Magnetic nano-'shepherds' organize cells
(Date:9/19/2014)... regulate their symbiotic relationship with soil bacteria by ... plant structure from leaves into the roots to ... roots. This collaborative study was conducted by researchers ... Graduate University for Advanced Studies (SOKENDAI), and the ... , Legumes, an important plant family which ...
(Date:9/18/2014)... Miranda, a small, icy moon of Uranus, is one ... the solar system. Despite its relatively small size, Miranda ... that resulted in the formation of at least three ... coronae. , These coronae are visible in Miranda,s ... km across. Arden corona, the largest, has ridges and ...
(Date:9/18/2014)... "frequent flyers" program, fruit flies surely would be eligible ... increasing numbers of fruit fly research studies. One fruit ... and another is scheduled launch to the station Sept. ... December. , Fruit flies are biomedical research models studied ... organisms can reveal the basis for health and disease ...
Breaking Biology News(10 mins):For legume plants, a new route from shoot to root 2Miranda: An icy moon deformed by tidal heating 2Miranda: An icy moon deformed by tidal heating 3Miranda: An icy moon deformed by tidal heating 4Miranda: An icy moon deformed by tidal heating 5Miranda: An icy moon deformed by tidal heating 6Miranda: An icy moon deformed by tidal heating 7Buzzing with activity: Fruit flies orbit Earth for science 2Buzzing with activity: Fruit flies orbit Earth for science 3Buzzing with activity: Fruit flies orbit Earth for science 4
... of the tyrannosaurid, says a University of Alberta researcher ... turn the animal into a "zoological superweapon." , ... tyrannosaurids," said Dr. Eric Snively, a post doctoral research ... instance, was keeping the T. rexes from breaking their ...
... is virus as for example HIV and bird flu able ... the purpose of the virus? Researchers at the University of ... is a collaboration between molecular biologists and physicists. ”The molecular ... the interplay between the intercellular parts, while the physicists have ...
... get older. As sleep quality and quantity typically decrease ... a healthy older man gets can affect his level of ... the April 1st issue of the journal SLEEP. , The ... of Chicago, focused on 12 healthy men between the ages ...
Cached Biology News:Fused nasal bones helped tyrannosaurids dismember prey 2Danish researches solve virus puzzle 2
(Date:9/19/2014)... , September 19, 2014 The new ... Spain , available today on PharmaBoardroom.com for ... Eurozone crisis that rocked the Spanish economy in 2009, and ... pharma community has remained pragmatic in times of trouble. ... still the fifth biggest European market, and the general conditions ...
(Date:9/18/2014)... A novel robotic system that can operate ... being tested as part of a biomedical research partnership ... the aim of determining if the robot, in conjunction ... faster, more accurate, less costly, and less discomforting for ... to deliver prostate cancer therapies with greater precision. , ...
(Date:9/18/2014)... , Sept. 18, 2014 Research and ... "Global and Chinese Stem Cell Industry Report, 2014-2017" ... are undifferentiated biological cells that can differentiate into specialized ... stem cells. Stem cell therapy can be applied to ... system disease), nervous system diseases, damage or lesion of ...
(Date:9/18/2014)... 2014  U.S. biotech company Kultevat has ... for technology developed by the Donald Danforth Plant ... including for applications in production of natural rubber in ... was developed under the direction of Roger Beachy ... president of the Danforth Plant Science Center, and is ...
Breaking Biology Technology:PharmaBoardroom Releases New Spain Pharmaceuticals Report 2PharmaBoardroom Releases New Spain Pharmaceuticals Report 3Worcester Polytechnic Institute Participates in Clinical Trial for MRI-Compatible Robot Designed to Improve Accuracy of Prostate Cancer Biopsies 2Worcester Polytechnic Institute Participates in Clinical Trial for MRI-Compatible Robot Designed to Improve Accuracy of Prostate Cancer Biopsies 3Worcester Polytechnic Institute Participates in Clinical Trial for MRI-Compatible Robot Designed to Improve Accuracy of Prostate Cancer Biopsies 4Worcester Polytechnic Institute Participates in Clinical Trial for MRI-Compatible Robot Designed to Improve Accuracy of Prostate Cancer Biopsies 5Worcester Polytechnic Institute Participates in Clinical Trial for MRI-Compatible Robot Designed to Improve Accuracy of Prostate Cancer Biopsies 6Global and Chinese Stem Cell Industry Report, 2014-2017 2Global and Chinese Stem Cell Industry Report, 2014-2017 3Kultevat obtains license of gene switch technology 2
... /PRNewswire-FirstCall/ - Oncolytics Biotech Inc.,("Oncolytics") (TSX:ONC, NASDAQ:ONCY) ... Administration (FDA) review, the Company is initiating ... administration of REOLYSIN(R) in,combination with paclitaxel and ... cancers. The Principal Investigator is Dr. Monica ...
... but powerful engine that propels the bacterium Bacillus ... flagellum by a protein clutch, Indiana University Bloomington and ... this week,s Science . , Scientists have ... what causes the flagellum to stop spinning -- temporarily ...
... As President Of ... AeroLEF Division -, ... , TSX: YM, AIM: YMBA), an oncology company that identifies,develops and ... imposed by the US Food and Drug,Administration (FDA) on the development ...
Cached Biology Technology:Oncolytics Biotech Inc. Announces U.S. Phase 2 Clinical Trial Investigating REOLYSIN(R) in Combination with Paclitaxel and Carboplatin 2Oncolytics Biotech Inc. Announces U.S. Phase 2 Clinical Trial Investigating REOLYSIN(R) in Combination with Paclitaxel and Carboplatin 3Microscopic 'clutch' puts flagellum in neutral 2Microscopic 'clutch' puts flagellum in neutral 3YM BIOSCIENCES ANNOUNCES FDA LIFTS CLINICAL HOLD ON AEROLEF(R) AND CLEARANCE OF A PHASE II CLINICAL TRIAL 2YM BIOSCIENCES ANNOUNCES FDA LIFTS CLINICAL HOLD ON AEROLEF(R) AND CLEARANCE OF A PHASE II CLINICAL TRIAL 3