Navigation Links
Magnetic nano-'shepherds' organize cells
Date:3/31/2009

DURHAM, N.C. -- The power of magnetism may address a major problem facing bioengineers as they try to create new tissue -- getting human cells to not only form structures, but to stimulate the growth of blood vessels to nourish that growth.

A multidisciplinary team of investigators from Duke University, Case Western Reserve University and the University of Massachusetts, Amherst created an environment where magnetic particles suspended within a specialized solution act like molecular sheep dogs. In response to external magnetic fields, the shepherds nudge free-floating human cells to form chains which could potentially be integrated into approaches for creating human tissues and organs.

The cells not only naturally adhere to each other upon contact, the researchers said, but the aligned cellular configurations may promote or accelerate the creation and growth of tiny blood vessels.

"We have developed an exciting way of using magnetism to manipulate human cells floating freely in a solution containing magnetic nanoparticles" said Randall Erb, fourth-year graduate student in the laboratory of Benjamin Yellen, assistant professor of Mechanical Engineering and Materials Science, at Duke University's Pratt School of Engineering. "This new cell assembly process holds much promise for tissue engineering research and offers a novel way to organize cells in an inexpensive, easily accessible way."

Melissa Krebs, third-year biomedical engineering graduate student at Case Western and Erb's sister, co-authored a paper appearing online in advance of the May publication of Nano Letters, a journal published by the American Chemical Society.

"The cells have receptors on their surfaces that have an affinity for other cells," Krebs said. "They become sticky and attach to each other. When endothelial cells get together in a linear fashion, as they did in our experiments, it may help them to organize into tiny tubules."

T
'/>"/>

Contact: Richard Merritt
richard.merritt@duke.edu
919-660-8414
Duke University
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Magnetic snakes control fluids, gravity-defying droplets, and solving a dragonfly mystery
2. Do migratory birds see the magnetic field?
3. New magnetic separation technique might detect multiple pathogens at once
4. New system would use rotating magnetic field to detect pathogens
5. UVa biomedical engineering study shows magnetic field can reduce swelling
6. Biomagnetics developed for use in new breast cancer tests
7. Researchers mimic bacteria to produce magnetic nanoparticles
8. Caltech geobiologists discover unique magnetic death star fossil
9. Electromagnetic phantom exorcises specters of metal detector tests
10. Magnetic nanoparticles navigate therapeutic genes through the body
11. Changing environment organizes genetic structure

Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Magnetic nano-'shepherds' organize cells
Magnetic nano-'shepherds' organize cells
(Date:12/1/2009)...o the radio anymore. They,re used in everything fr... Carolina State University is revolutionizing the ...ntennas that open the door to a host of new uses i...ployment. , Modern antennas are made from copper... far they can be bent and how often before they ...
(Date:11/30/2009)...d to monitor the commitments that will be made by ...forestation rates, according to research at the Un...s and research groups have failed to make full use...,s surface collected each week to monitor tropical...Grainger in the Proceedings of the National Acade...
(Date:11/30/2009)...ert at the holiday table are even less of a help t...g to a new research report recently appearing onli...), a diet that is high in fat and in sugar actuall...es to store too much fat. This means these foods h...lt task of converting high-fat and high-sugar food...
Breaking Biology News(10 mins):Shape shifters: Researchers create new breed of antennas 2World forest observatory needed to monitor vital role of forests in climate deal 2Happy holidays from the groaning board; Western diets turn on fat genes 2USC Keck School of Medicines Dr Alan Epstein Receives Prestigious National Cancer Institute RAID Award for Breakthrough IL 2 Molecule Therapeutic 4693 1USC Keck School of Medicines Dr Alan Epstein Receives Prestigious National Cancer Institute RAID Award for Breakthrough IL 2 Molecule Therapeutic 4693 2USC Keck School of Medicines Dr Alan Epstein Receives Prestigious National Cancer Institute RAID Award for Breakthrough IL 2 Molecule Therapeutic 4693 3USC Keck School of Medicines Dr Alan Epstein Receives Prestigious National Cancer Institute RAID Award for Breakthrough IL 2 Molecule Therapeutic 4693 4Leading Experts Endorse Biohearts Muscle Stem Cell MyoCell Therapy 4691 1Leading Experts Endorse Biohearts Muscle Stem Cell MyoCell Therapy 4691 2Leading Experts Endorse Biohearts Muscle Stem Cell MyoCell Therapy 4691 3Leading Experts Endorse Biohearts Muscle Stem Cell MyoCell Therapy 4691 4New Weapon Emerges to Fight Kids Cavities 50876 1New Weapon Emerges to Fight Kids Cavities 50876 2
... the National Institutes of Health, scientists at ...k, hope to understand how the malaria parasite Pla...effective medication chloroquine. , Malaria is re...hom are children under 5 in sub-Saharan Africa, sa...y and biological sciences, principal investigator ...
... transgenic crops are the focus of numerous invest... PloS ONE, which was carried out by Cristina Faria...Turlings, professor in chemical ecology at the Uni... most transgenic maize lines were significantly mo...han their conventional equivalents. "We have studi...
...emical warfare has been around a lot longer than p...100 million years, give or take a little. , A new...as identified a soldier beetle, preserved almost p...ng chemical repellants to fight off an attacker wh...r eternity. , The discovery is the earliest fossi...
Other Biology News:Binghamton University researchers investigate evolving malaria resistance 2Transgenic maize is more susceptible to aphids 2Amber specimen captures ancient chemical battle 2Amber specimen captures ancient chemical battle 3
(Date:12/1/2009)..., NEW YORK, Dec. 1 Reportlinker...s available in its catalogue: ,, Emerging Clin...mics and the changing healthcare and regulatory en...5658/Emerging-Clinical-Trial-Locations---Eastern-E...and-regulatory-environment.html ,, Over the la...
(Date:12/1/2009)... , CAMBRIDGE, Mass., Dec. 1 To ...ustry and to promote its potential, a group of ind...the Synthetic Biology Industry Association (SynBIA...of the association is to provide a forum for indiv... industry, address its opportunities and its chall...
(Date:12/1/2009)... SHANGHAI, Dec. 1 /PRNewswire-Asia/ -- Shanghai...harma, a leading China-based Contract Research,Org... the 2009 Deloitte,Technology Fast 50 China, ranki...h companies in China. The award is a testament to ...h from 2006 to 2008. , The results of the...
(Date:12/1/2009)..., SPRINGFIELD, Ill., Dec. 1 Prairi...announce that it was recently awarded two statuett...on Nov. 13 in New York City. The CLIO Healthcare A...n in the healthcare advertising industry and is an...most recognized awards competitions for advertisin...
Breaking Biology Technology:Reportlinker Adds Emerging Clinical Trial Locations - Eastern Europe: Market Dynamics and the Changing Healthcare and Regulatory Environment 2Reportlinker Adds Emerging Clinical Trial Locations - Eastern Europe: Market Dynamics and the Changing Healthcare and Regulatory Environment 3Reportlinker Adds Emerging Clinical Trial Locations - Eastern Europe: Market Dynamics and the Changing Healthcare and Regulatory Environment 4Reportlinker Adds Emerging Clinical Trial Locations - Eastern Europe: Market Dynamics and the Changing Healthcare and Regulatory Environment 5Reportlinker Adds Emerging Clinical Trial Locations - Eastern Europe: Market Dynamics and the Changing Healthcare and Regulatory Environment 6Reportlinker Adds Emerging Clinical Trial Locations - Eastern Europe: Market Dynamics and the Changing Healthcare and Regulatory Environment 7Reportlinker Adds Emerging Clinical Trial Locations - Eastern Europe: Market Dynamics and the Changing Healthcare and Regulatory Environment 8Industry Forms Association to Address Opportunities and Challenges of Synthetic Biology 2Shanghai ChemPartner Ranks 3rd among 2009 Deloitte Technology Fast 50 China Winning Companies 2Shanghai ChemPartner Ranks 3rd among 2009 Deloitte Technology Fast 50 China Winning Companies 3Prairie Heart Institute of Illinois Wins Two CLIO Healthcare Awards 2
..., MELBOURNE, Australia, May 28 Cytopia Limited (A...y data from its Phase I clinical trial of orally a...merican Society of Clinical Oncologists (ASCO), in...coni, one of the clinical investigators for the pr...op m ental Therapeutics - Vascula r...
..., HORSHAM, Pa., May 28 Centocor Ortho Biotech Pro...everal compounds will be presented at the 45th Ame...eeting in Orlando, Fla., from May 29 to June 2, 20...Biotech Products, L.P. or its research partner, Or...nit of Johnson & Johnson Pharmaceutical Resear...
..., NEENAH, Wis., May 28 Plexus Corp. (Nasdaq: PL...develop QIAGEN,s next generation automated screeni...avirus (HPV) DNA samples. This product provides a...cess, through sophisticated robotic motions. QIAG... HPV; a virus that has an established link to cerv...
Other Biology Technology:Oral VDA CYT997 - Phase I Clinical Trial Presentation at ASCO 2Centocor Ortho Biotech Data to be Presented at American Society of Clinical Oncology (ASCO) Annual Meeting 2Centocor Ortho Biotech Data to be Presented at American Society of Clinical Oncology (ASCO) Annual Meeting 3Centocor Ortho Biotech Data to be Presented at American Society of Clinical Oncology (ASCO) Annual Meeting 4Centocor Ortho Biotech Data to be Presented at American Society of Clinical Oncology (ASCO) Annual Meeting 5Centocor Ortho Biotech Data to be Presented at American Society of Clinical Oncology (ASCO) Annual Meeting 6Centocor Ortho Biotech Data to be Presented at American Society of Clinical Oncology (ASCO) Annual Meeting 7Centocor Ortho Biotech Data to be Presented at American Society of Clinical Oncology (ASCO) Annual Meeting 8Centocor Ortho Biotech Data to be Presented at American Society of Clinical Oncology (ASCO) Annual Meeting 9Centocor Ortho Biotech Data to be Presented at American Society of Clinical Oncology (ASCO) Annual Meeting 10Centocor Ortho Biotech Data to be Presented at American Society of Clinical Oncology (ASCO) Annual Meeting 11Plexus Awarded Development Contract With QIAGEN 2Plexus Awarded Development Contract With QIAGEN 3Plexus Awarded Development Contract With QIAGEN 4
...0 pro UV/Visible Spectrophotometer: *,Meets the d...s of instrument specification and GLP self-diagnos...or rapid, discrete measurements., *Bandwidth of 1.... read high performance deuterium and tungsten lamp...
Cultrex BME with phenol red from Trevigen
Human CCL21 / 6Ckine, Unconjugated, Fc Chimera from R&D Systems
Rabbit Anti-NPM1 Polyclonal Antibody, Unconjugated from Proteintech Group, Inc.
Biology Products: