Navigation Links
Magnet Lab researchers make observing cell functions easier
Date:5/8/2008

on, acidity changes -- just about any cellular process that can occur.

In FRET, two molecules that are fluorescent act as molecular beacons under the microscope, transferring energy between each other if they interact in the living cell, said Davidson, who directs the magnet labs Optical Microscopy program. With FRET, we can see that happen, but until now, we have only been able to monitor one biosensor at a time.

The new technique, called Dual FRET, is outlined in the paper Fluorescent Protein FRET Pairs for Ratiometric Imaging of Dual Biosensors. http://www.nature.com/nmeth/journal/v5/n5/abs/nmeth.1207.html

Further expanding the capabilities of optical microscopy, Davidson and his team worked with collaborators from the University of California, San Diego to create a new screening method for fluorescent proteins that makes them more stable under the microscope. These proteins are sensitive to light, which can bleach them out after a certain period of time. By making the proteins more stable, microscopists can observe live cell dynamics for longer periods of time. The paper describing their work, Improving the Photostability of Bright Monomeric Orange and Red Fluorescent Proteins, was published in the May 4 online edition of Nature Methods. http://www.nature.com/nmeth/journal/v4/n9/full/nmeth1083.html

Taken together, the new technique and tool are expected to speed up experiments and expand the utility of optical microscopy by allowing two dynamic processes inside a cell to be observed at once -- and for longer periods of time.


'/>"/>

Contact: Michael Davidson
davidson@magnet.fsu.edu
850-644-0542
Florida State University
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Magnetic snakes control fluids, gravity-defying droplets, and solving a dragonfly mystery
2. Do migratory birds see the magnetic field?
3. New magnetic separation technique might detect multiple pathogens at once
4. New system would use rotating magnetic field to detect pathogens
5. UVa biomedical engineering study shows magnetic field can reduce swelling
6. Biomagnetics developed for use in new breast cancer tests
7. Researchers mimic bacteria to produce magnetic nanoparticles
8. Researchers identify proteins involved in new neurodegenerative syndrome
9. Texas researchers and educators head for Antarctica
10. MGH researchers describe new way to identify, evolve novel enzymes
11. University of Pennsylvania researchers develop formula to gauge risk of disease clusters
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Magnet Lab researchers make observing cell functions easier
(Date:1/22/2015)... , Jan. 21, 2015  Analyst Report Issued by Small ... Brands report showed that planet-wide, transactions at merchants on the ... the total number of credit, debit, and prepaid cards reached ... were victims of fraudulent card usage in 2012, and credit ...
(Date:1/22/2015)... NEW YORK , Jan. 22, 2015   EyeLock, Inc. ... announced it has appointed Steve Gerber to the ... Gerber will be responsible for leading development of mobile platforms ... 25 years of success and innovation in the semiconductor industry ...
(Date:12/22/2014)... Inc. (NASDAQ: NXTD and NXTDW) ("NXT-ID" or ... mobile commerce market, announces it has retained famous pickpocket, entertainer ... International CES debut of the Wocket™ biometric smart wallet.  ... NXT-ID booth January 6th and 7 th , 2015, demonstrating ...
Breaking Biology News(10 mins):$4.80 Near Term Price Target with "Buy" given by CapRock Research for NXT-ID, Inc. (NASDAQ: NXTD) issued by Small Cap IR 2EyeLock Names Steve Gerber as Senior Vice President of Mobile and Wearables 2NXT-ID Hires Master Pickpocket and Security Consultant Apollo Robbins for Wocket Smart Wallet CES 2015 Debut 2NXT-ID Hires Master Pickpocket and Security Consultant Apollo Robbins for Wocket Smart Wallet CES 2015 Debut 3NXT-ID Hires Master Pickpocket and Security Consultant Apollo Robbins for Wocket Smart Wallet CES 2015 Debut 4
... Tuesday, Nov. 16, 2010 Tying in with ... new pre-conference workshops will debut at this year,s TERMIS-North ... Orlando, Fla. The TERMIS (Tissue Engineering & ... by the Wake Forest Institute for Regenerative Medicine, and ...
... brink of an era of mass extinctions similar to ... disappeared from the Earth, reports a biologist at Penn ... a species-rescue program for Haiti,s threatened frogs and other ... few decades, many Haitian species of plants and animals ...
... SAN DIEGO New research indicates that the ... About two percent of the population has a condition called ... are experienced at once. Although this condition is rare, the ... sometimes overlapping ways to help people interpret and understand their ...
Cached Biology News:Regenerative medicine workshops to debut at TERMIS North America Annual Conference 2Rescue missions underway to save Haiti's species from mass extinctions 2Rescue missions underway to save Haiti's species from mass extinctions 3Rescue missions underway to save Haiti's species from mass extinctions 4Rescue missions underway to save Haiti's species from mass extinctions 5Hearing colors, seeing sounds: New research explores sensory overlap in the brain 2
(Date:1/22/2015)... 22. 2015  Varian Medical Systems (NYSE: VAR ), ... for its commitment to sustainability with inclusion on a prestigious ... highest ranked healthcare equipment company among the Corporate Knights Global ... Economic Forum at Davos, Switzerland . ...
(Date:12/24/2014)... , Dec. 24, 2014  United Therapeutics Corporation (NASDAQ: ... MDT ) has submitted a pre-market approval ... for the use of Medtronic,s SynchroMed ® II ... for use with United Therapeutics, Remodulin ® (treprostinil) ...
(Date:12/24/2014)... 2014 “Preparative & Process Chromatography ... Consumables (Columns, Solvents, Buffers, Valves, Guages, Seals), Accessories, ... - Forecasts to 2019” provides a detailed overview ... market trends, and strategies impacting the preparative and ...
(Date:12/24/2014)... Bethesda, MD (PRWEB) December 23, 2014 ... law H.R. 83, the Omnibus and Continuing Resolution Appropriations ... hydrocephalus a condition eligible to receive funding through the ... Department of Defense (DoD). The Hydrocephalus Association (HA), working ...
Breaking Biology Technology:Varian Honored Among World's 100 Most Sustainable Corporations 2United Therapeutics Announces Submission Of Pre-Market Approval Application For Implantable Drug Infusion System To Deliver Remodulin 2United Therapeutics Announces Submission Of Pre-Market Approval Application For Implantable Drug Infusion System To Deliver Remodulin 3United Therapeutics Announces Submission Of Pre-Market Approval Application For Implantable Drug Infusion System To Deliver Remodulin 4Preparative and Process Chromatography Market is expected to reach $9 billion by 2019 - New Report by Marketsandmarkets 2Preparative and Process Chromatography Market is expected to reach $9 billion by 2019 - New Report by Marketsandmarkets 3Preparative and Process Chromatography Market is expected to reach $9 billion by 2019 - New Report by Marketsandmarkets 4Rare Brain Condition Now Eligible for Department of Defense Research Dollars 2
... Neuftec,Limited, the proprietor of the original nano-particulate ... claim against Oxonica Energy,Limited, a wholly owned subsidiary ... in the High Court of Justice, has commented ... by Dr Matthews,(CEO) on 19 June 2008., ...
... have invented an affordable technique that uses lasers and ... needed for new generations of microchips. , The ... times narrower than a human hair, may enable the ... applications in medicine, optical communications, computing and sensor technologies. ...
... June 18 ,Exelixis, Inc. (Nasdaq: EXEL ) announced ... officer at Exelixis, will present at the,Piper Jaffray Europe ... time on Wednesday, June 25, 2008. Mr. Karbe will ... The presentation will be webcast and may be ...
Cached Biology Technology:Neuftec Responds to a Fundamental Inaccuracy in Oxonica PLC's Regulatory Announcement 2Trap and zap: Harnessing the power of light to pattern surfaces on the nanoscale 2Trap and zap: Harnessing the power of light to pattern surfaces on the nanoscale 3
Formula variant: With macro- and micronutrients. Physical Form: powder Suitab tst: plant cell culture tested...
... Analyzer for superior sensitivity, mass accuracy, and resolving power., Specifications:, ... ion selection range: 150 - 4000 m/z, * Resolution: 14,000 (1400 ... * Dynamic range: 4 orders of magnitude ... ...
... PHD2000 syringe pump series combines Harvard Apparatuss best ... and a wide range of configuration options. A ... dimensions of syringes from all the major manufacturers. ... all the pertinent information from across the lab. ...
Mouse monoclonal antibody to RAD51L3 - RAD51-like 3 (S. cerevisiae)...
Biology Products: