Navigation Links
Macrophages: The 'defense' cells that help throughout the body
Date:8/26/2010

Westminster, Colo. (August 26, 2010) The term "macrophage" conjures images of a hungry white blood cell gobbling invading bacteria. However, macrophages do much more than that: Not only do they act as antimicrobial warriors, they also play critical roles in immune regulation and wound-healing. They can respond to a variety of cellular signals and change their physiology in response to local cues.

David Mosser, Professor of Cell Biology and Molecular Genetics at the University of Maryland's College of Chemical and Life Sciences, will discuss the three primary duties of macrophages at the 2010 American Physiological Society conference, Inflammation, Immunity, and Cardiovascular Disease, in Westminster Colorado, August 25-28. The full conference program can be found at http://the-aps.org/meetings/aps/inflammation/.

"There has been a huge outpouring of research about host defense that has overshadowed the many diverse activities that these cells do all the time," said Dr. Mosser. "We'd like to dispel the narrow notion that most people have that macrophages' only role is defense, and expand it to include their role in homeostasis."

Monocyte Differentiation

Macrophages exist in nearly all tissues and are produced when white blood cells called monocytes leave the blood and differentiate in a tissue-specific manner. The type of macrophage that results from monocyte differentiation depends on the type(s) of cytokines that these cells encounter. Cytokines are proteins produced by immune cells that can influence cell behavior and affect interactions between cells. For example, macrophages that battle microbial invaders arise in response to interferon-γ, a cytokine that is produced during a cellular immune response involving helper T-cells and the factors they produce. These macrophages are considered to be "classically activated."

However, when monocyte
'/>"/>

Contact: Donna Krupa
DKrupa@the-aps.org
301-634-7209
American Physiological Society
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. What causes cell defenses to crumble?
2. Researchers recreate SARS virus, open door for potential defenses against future strains
3. New dummy design and development wins US Department of Defense award
4. Lockheed Martin Team Wins Role on Key Department of Defense Biometrics Contract Vehicle
5. Raytheon Chosen to Help Provide Department of Defense Biometrics Operations and Support Services
6. ASM biodefense and emerging diseases research meeting
7. SectorWatch.biz Issues Commentary for Investors of Homeland Defense Companies FOUR, MAGS, NSSC, PNTR, BCO, and CKP
8. CSC Awarded Department of Defense Biometrics Contract
9. Understanding natural crop defenses
10. Reforming defense department acquisition policy: UM expert
11. Researchers discover primer to plant defense system
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2014)... The enormous conflagration known as the Rim Fire was ... among mature trees, when it entered the backcountry of ... August 2013. But inside the park, the battle began ... management decisions and drought can combine to fuel large, ... park, it eventually encountered lands where fire had been ...
(Date:7/31/2014)... Florida State University researcher found that bacteria in the ... of the oil released during the Deepwater Horizon spill ... most toxic contaminants. , In two new studies conducted ... found a species of bacteria called Colwellia ... and xylene compounds that were released as part of ...
(Date:7/31/2014)... July 31, 2014 NXT-ID, Inc., (NXTD: OTCQB) a ... market, reminds investors and consumers wanting to learn ... it will be on-air today, July 31 st ... wallet will be featured in a segment of ... that airs on the History Channel, FYI Network ...
Breaking Biology News(10 mins):The Rim Fire 1 year later: A natural experiment in fire ecology and management 2The Rim Fire 1 year later: A natural experiment in fire ecology and management 3The Rim Fire 1 year later: A natural experiment in fire ecology and management 4The Rim Fire 1 year later: A natural experiment in fire ecology and management 5NXT-ID's Next Generation Biometric Smart Wallet Featured on NewsWatch Consumer Show on the History Channel and FYI Network Today, July 31st 2NXT-ID's Next Generation Biometric Smart Wallet Featured on NewsWatch Consumer Show on the History Channel and FYI Network Today, July 31st 3
... led by Johns Hopkins scientists has,found the first ... immune,system's remarkable ability to recognize and respond to ... family of genes whose,only apparent function is to ... cut themselves out of the genetic material, and ...
... Health Department today issued a public health advisory after reporting ... highly drug resistant strain of HIV in a New York ... have occurred in mid-October 2004, to a largely untreatable strain ... health officials, the man -- who had previously had five ...
... President and Director of Research at the ... ,the release of a new approach to simulation ... of Nature,Biotechnology.,The research article, entitled "Automatic generation ... ,describes MSI's discrete stochastic event simulator, which keeps ...
Cached Biology News:UCSD Discovery Shows How Embryonic Stem Cells Perform 'Quality Control' Inspections 2UCSD Discovery Shows How Embryonic Stem Cells Perform 'Quality Control' Inspections 3NYC's First Rapid HIV Drug-resistant AIDS Case Prompts Call to Step Up HIV Prevention 2MSI releases 'moleculizer' - a new approach to simulation of intracellular biochemical networks 2MSI releases 'moleculizer' - a new approach to simulation of intracellular biochemical networks 3
(Date:7/31/2014)... reason people over 60 are not donor candidates for ... with time, making the elderly prone to life-threatening infection ... team now has discovered a reason why. , "We ... of blood-forming cells to maintain blood production over time ... that could be restored for rejuvenation therapies," said Emmanuelle ...
(Date:7/31/2014)... 31, 2014 The SNIS Foundation recognized ... to fund a translational research project.  The first ... gift was presented at the Society of NeuroInterventional ... Colorado Springs, CO. ... to neurovascular conditions, SNIS formed the SNIS Foundation, ...
(Date:7/31/2014)... 2014 According to a new ... Medical Devices Market (Diagnostic Electrodes - ECG, EEG, EMG, ... Pacemakers, Defibrillators, Electrosurgical and Other Electrodes) - Global Industry ... 2019," the global electrodes market for medical devices was ... estimated to reach a market worth USD 1,451.2 million ...
(Date:7/31/2014)... China , July 31, 2014 ... Irys™System by BGI , the world,s ... comprehensive exploration of human structural variation (SV) and to ... including those where no reference exists. In addition, BioNano ... for multiplexing on the Irys System, enabling significantly higher ...
Breaking Biology Technology:Key to aging immune system is discovered 2SNIS Foundation Bestows First Grant Award For Cutting-Edge NeuroInterventional Research 2SNIS Foundation Bestows First Grant Award For Cutting-Edge NeuroInterventional Research 3Electrodes for Medical Devices Market Expected to Reach USD 1.45 Billion Globally in 2019: Transparency Market Research 2Electrodes for Medical Devices Market Expected to Reach USD 1.45 Billion Globally in 2019: Transparency Market Research 3Electrodes for Medical Devices Market Expected to Reach USD 1.45 Billion Globally in 2019: Transparency Market Research 4Electrodes for Medical Devices Market Expected to Reach USD 1.45 Billion Globally in 2019: Transparency Market Research 5Electrodes for Medical Devices Market Expected to Reach USD 1.45 Billion Globally in 2019: Transparency Market Research 6BioNano Genomics Announces the Purchase of the Irys System by BGI 2BioNano Genomics Announces the Purchase of the Irys System by BGI 3BioNano Genomics Announces the Purchase of the Irys System by BGI 4
... H. Paul Dorman, Chairman,and Chief Executive Officer of ... has signed a definitive agreement to sell its,dermatology ... VRX )., Under the terms of ... shares of Coria from DFB Pharmaceuticals, Inc., and ...
... today announced that for the second year, it will ... hospitals, health systems and,community health clinics improve patient safety ... Patient Safety Grant Program in August,2007 as the first ... sector, and,received applications from more than 10 percent of ...
... 17 Quark Pharmaceuticals, Inc.,a development-stage ... interference (RNAi)-based therapeutics, today announced the,presentation ... RNAi Europe, taking place,September 16-18, 2008 ... scientists,Igor Mett, Hagar Kalinski, and Hagit ...
Cached Biology Technology:DFB Sells Coria Labs to Valeant Pharmaceuticals 2DFB Sells Coria Labs to Valeant Pharmaceuticals 3Cardinal Health Invites Health Care Providers to Apply for $1 Million in Grants to Fund Patient Safety Initiatives 2Cardinal Health Invites Health Care Providers to Apply for $1 Million in Grants to Fund Patient Safety Initiatives 3Quark Pharmaceuticals Announces Poster Presentations at RNAi Europe 2008 2Quark Pharmaceuticals Announces Poster Presentations at RNAi Europe 2008 3
HRP Monoclonal-Goat Diluent - 5X Concentrate, 25 mL...
Rabbit anti-Junctophilin-4 (C-term)...
... CopyControl™ PCR Cloning Kits are designed to speed ... that all PCR products, regardless of sequence or ... PCR products including those that are difficult to ... may be unstable or code for potentially detrimental ...
Size & Applications: 20 ml Storage Temp.: -20C Shelf Life: 12 months ...
Biology Products: