Navigation Links
MU research sheds light on nerve regeneration following spinal cord injury
Date:11/21/2013

COLUMBIA, Mo. Fish, unlike humans, can regenerate nerve connections and recover normal mobility following an injury to their spinal cord. Now, University of Missouri researchers have discovered how the sea lamprey, an eel-like fish, regrows the neurons that comprise the long nerve "highways" that link the brain to the spinal cord. Findings may guide future efforts to promote recovery in humans who have suffered spinal cord injuries.

"There is a lot of attention to why, following a spinal cord injury, neurons regenerate in lower vertebrates, such as the sea lamprey, and why they don't in higher vertebrates, such as humans," said Andrew McClellan, professor of biological sciences in the College of Arts and Science and director of the MU Spinal Cord Injury Program.

The study focuses on the regrowth of a particular group of nerve cells called reticulospinal neurons, which are necessary for locomotion. These neurons are found in the hindbrain, or the brainstem, and send signals to the spinal cord of all vertebrates to control movements of the body, such as locomotor behavior. When these nerve cells are damaged by a spinal cord injury, the animal is unable to move below the level of injury. While humans and other higher vertebrates would be permanently paralyzed, the sea lamprey and other lower vertebrates have the ability to regrow these neurons and recover the ability to move within a few short weeks.

In the study, McClellan and his colleagues isolated and removed injured reticulospinal neurons from sea lamprey and grew them in cultures. They applied chemicals that activated a group of molecules, called second messengers, to see what effects they had on these neurons' growth. They discovered that activation of cyclic AMP, a molecule that relays chemical signals inside cells, acted somewhat like an "on" switchessentially converting neurons from a non-growing state to a growing one. However, it had no effect on neurons that had already
'/>"/>

Contact: Jeff Sossamon
sossamonj@missouri.edu
573-882-3346
University of Missouri-Columbia
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Researchers gain fuller picture of cell protein reactions
2. Scripps oceanography researchers engineer breakthrough for biofuel production
3. USF researchers show invasive sparrows immune cells sharpen as they spread
4. Researchers use CT and 3-D printers to recreate dinosaur fossils
5. Natural compound mitigates effects of methamphetamine abuse, University of Missouri researchers find
6. Researchers classify urban residential desert landscapes
7. Researchers test effects of LEDs on leaf lettuce
8. Researchers develop new approach to identify possible ecological effects of releasing genetically engineered insects
9. Researchers capture structure of key part of deadly Nipah virus
10. Researchers identify main genes responsible for asthma attacks in children
11. Bait research focused on outsmarting destructive beetle
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
MU research sheds light on nerve regeneration following spinal cord injury
(Date:12/17/2014)... , Dec. 15, 2014  HITLAB SM ... Practices (GCP) audit to confirm its adherence to ... This accomplishment enables HITLAB to conduct regulated smart ... highest principles for patient safety and research quality. ... healthcare access, quality, and delivery with innovative technology," ...
(Date:12/17/2014)... -- Automation is fundamentally transforming the travel experience and ... borders. Over the past decade, ePassports, biometric readers, ... to self process through border control via eGates ... increasing number of airports, seaports, and land borders ... Maxine Most , Principal at Acuity Market ...
(Date:12/11/2014)... , Dec. 09, 2014 Research and ... ( http://www.researchandmarkets.com/research/9ql3kr/biometrics_market ) has ... in India 2015-2019" report to their offering. ... this market is the adoption of multimodal biometric ... characteristic of an individual for verification and identification ...
Breaking Biology News(10 mins):HITLAB Completes GCP Audit for FDA Smart Device & App Compliance 2Automated Border Control (ABC) Transforms the Global Travel Experience With More Than 2500 ABC eGates and APC Kiosks Deployed In Airports, Seaports, and Land Borders Worldwide 2Biometrics Market in India 2015-2019: Key Vendors are 3M Cogent, NEC, Safran and Suprema 2
... The way indigenous cultures around the globe use,traditional medicines ... linked to the,natural environment, new research has found. ... threat that comes on top of the challenges posed ... for more than half the world,s population, with 80 ...
... Energy,s (DOE,s) Office of Science and its labs will be ... AAAS Annual Meeting,CHICAGO Attendees of the 2014 AAAS Annual ... DOE,s Office of Science and its labs will play an ... President,s Address ,2014 AAAS co-chair ...
... PITTSBURGH, Feb. 13, 2014 University of Pittsburgh Cancer Institute ... to do new tricks., By screening a library of FDA-approved ... treatment for a rare type of cancer, UPCI scientists were ... the cancer becomes resistant to standard drug treatment., The discovery, ...
Cached Biology News:Environment change threatens indigenous know-how 2Department of Energy speakers and sessions at AAAS 2Department of Energy speakers and sessions at AAAS 3Department of Energy speakers and sessions at AAAS 4Department of Energy speakers and sessions at AAAS 5Department of Energy speakers and sessions at AAAS 6Laboratory detective work points to potential therapy for rare, drug-resistant cancer 2
(Date:12/22/2014)... Dec. 22, 2014  ( www.competitivehealth.com ) — Competitive ... medical bill review and advocacy service, has signed an ... WellCard Savings discount health services marketplace. 63% ... more than they expected to pay. As part of ... costs, WellCard Savings is pleased to offer medical bill ...
(Date:12/22/2014)... 22, 2014 Fertility Associates of Memphis ... Bank USA , a network of more than 20 ... partnership, patients have fast access to a national pool ... IVF . Fertility Associates of Memphis is the only ... treatment option. , Dr. William Kutteh , director ...
(Date:12/19/2014)... BioPlus Specialty Pharmacy (BioPlus), one ... of Nick Maroulis, Pharm.D. to the newly created position ... In this position, Dr. Maroulis will continue to manage ... of our multi-site pharmacies as the company expands. Dr. ... that time he has served in many different capacities ...
(Date:12/19/2014)... Dec. 19, 2014 Bina Technologies, Inc. (Bina, ... that they have been acquired by Roche (SIX: RO, ... privately held company that provides a big data platform ... (NGS) data for the academic and translational research markets. ... and will continue to focus on development of their ...
Breaking Biology Technology:WellCard Savings Announces CoPatient Medical Bill Review Service for Members 2Fertility Associates of Memphis Announces Partnership with Donor Egg Bank USA 2Fertility Associates of Memphis Announces Partnership with Donor Egg Bank USA 3BioPlus Specialty Pharmacy Promotes Dr. Nick Maroulis to Vice President of Specialty Pharmacy Services 2Bina Technologies is acquired by Roche. 2Bina Technologies is acquired by Roche. 3
... -- Biostar,Pharmaceuticals, Inc. (OTC Bulletin Board: BSPM) ("Biostar" or "the Company"),a Xianyang-based developer, ... and conditions,today announced fiscal results for its second quarter ended June 30, 2009. ... Results, ... Q2 2009 Q2 ...
... ... Web 2.0 Website in an effort to not only provide circuit board assembly and design ... ... value to their current and future customers Surface Mount Solutions (SMS) has launched a new ...
... , , , ... ACTC) announced today that Dr. Robert Lanza, its Chief Scientific Officer, is ... 102 and 55 [Live Saturday 12 pm - 1 pm ET; Replays ... The show focuses on Dr. Lanza,s research at ACTC and his new ...
Cached Biology Technology:Biostar Pharmaceuticals, Inc. Announces Second Quarter 2009 Financial Results 2Biostar Pharmaceuticals, Inc. Announces Second Quarter 2009 Financial Results 3Biostar Pharmaceuticals, Inc. Announces Second Quarter 2009 Financial Results 4Biostar Pharmaceuticals, Inc. Announces Second Quarter 2009 Financial Results 5Biostar Pharmaceuticals, Inc. Announces Second Quarter 2009 Financial Results 6Biostar Pharmaceuticals, Inc. Announces Second Quarter 2009 Financial Results 7Biostar Pharmaceuticals, Inc. Announces Second Quarter 2009 Financial Results 8Biostar Pharmaceuticals, Inc. Announces Second Quarter 2009 Financial Results 9Biostar Pharmaceuticals, Inc. Announces Second Quarter 2009 Financial Results 10Biostar Pharmaceuticals, Inc. Announces Second Quarter 2009 Financial Results 11Surface Mount Solutions Launches New Website 2Dr. Robert Lanza is Featured Guest on Deepak Chopra's SIRIUS XM Stars Radio Show 2Dr. Robert Lanza is Featured Guest on Deepak Chopra's SIRIUS XM Stars Radio Show 3
... deparaffinize and perform Heat Induced Antigen Retrieval ... mounted on glass microscope slides. Deparffinization is ... high temperature used in HIER (over 90degrees ... by detergent. Formaldehyde fixation impairs or totally ...
... Bovine Calf Serum; U.S. ... seek an uncompromising quality; Low ... Collected from animals of US ... those who seek an uncompromising ...
Collected from animals of U.S. origin.Collected from animals of U.S. origin. *Can be used in cell growth studies and immunoassays. *Sterility tested, * Mycoplasma tested upon request, *Endoto...
...
Biology Products: