Navigation Links
MSU project may lead to new approaches against lung cancer
Date:8/17/2010

EAST LANSING, Mich. A Michigan State University researcher is analyzing the immune system's own ability to protect the body against lung cancer.

The results of the work by Alison Bauer, an assistant professor of pathobiology and diagnostic investigation in the College of Veterinary Medicine, are expected to provide new approaches to prevent, identify and treat lung cancer.

The research is funded by a $720,000 grant from the American Cancer Society.

"Chronic inflammatory lung diseases, such as asthma and chronic obstructive pulmonary disease, are risk factors in the development of lung cancer," Bauer explained. "However, activation of certain components of the immune system namely the part of our immune system that responds first to an injury, or the innate immune system may provide protection against lung cancer development."

Bauer explains her research entitled "The role of toll-like receptor 4 in mouse pulmonary neoplasia" as follows: Previous research has determined that farm and textile workers exposed to elevated levels of a bacterial component called endotoxin are at a reduced risk of developing lung cancer.

After being introduced to the body, endotoxin binds to a specific protein on cells known as "toll-like" receptors; these receptors are involved in innate immunity. The primary receptor binding endotoxin is called toll-like receptor 4 (TLR4).

Bauer and her team have previously shown that TLR4 acts in a protective manner against the development of chronic lung inflammation and lung cancer in mice; that research was published last year in the journal Molecular Cancer. With this grant, they will further investigate how and why TLR4 acts in a protective manner, focusing on the cells involved in the inflammation process in mice models.

Bauer also will look at intercellular communication, which is one way neighboring cells can communicate, and growth factor regulation. The team will inve
'/>"/>

Contact: Jason Cody
codyja@msu.edu
517-432-0924
Michigan State University
Source:Eurekalert

Page: 1 2

Related biology news :

1. Case Western Reserve University project ties soil conservation and river management together
2. Human Microbiome Project awards funds for technology development, data analysis and ethical research
3. Academy participates in project to discover drugs, biofuels in tropical seas
4. Field-hospital-on-a-chip project awarded to nanoengineer from UC San Diego
5. State fund advances titanium powder research, 9 other Iowa State projects
6. TECNALIA leads five projects within the VII Framework Program
7. Natural Capital Project to develop conservation software
8. Bangladesh Voter Registration Project Now Using MegaMatcher Biometric Technology to Detect and Prevent Duplicate Registrations
9. VUANCE Announces Crime Scene Security and Evidentiary Tracking Development Project
10. Human connection to our nations fisheries comes alive through oral history project
11. A BBVA Foundation project comes up with a system enabling detection of cetacean hearing loss
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/22/2014)... and you,re likely to find that the lunches and snacks ... of a study conducted by researchers at the Friedman School ... the Department of Public Health and Community Medicine at Tufts ... ahead of print in the Journal of the Academy ... author Jeanne Goldberg, Ph.D., R.D., a professor at the Friedman ...
(Date:7/22/2014)... immune cell widely believed to exacerbate chronic adult ... sclerosis (MS), can actually protect the brain from ... progression of neurodegenerative diseases, according to Cleveland Clinic ... Nature Communications . , The research team, led ... of Neurosciences at Cleveland Clinic,s Lerner Research Institute, ...
(Date:7/21/2014)... Middle East Respiratory Syndrome coronavirus (MERS-CoV) in the air ... virus. The work, published this week in mBio ... for Microbiology, indicates that further studies are needed to ... air. , MERS, a serious viral respiratory illness caused ... as of June 11, according to the World Health ...
Breaking Biology News(10 mins):Room for improvement in elementary school children's lunches and snacks from home 2Cleveland Clinic researchers discover neuroprotective role of immune cell 2Middle East Respiratory Syndrome coronavirus detected in the air of a Saudi Arabian camel barn 2
... a revolutionary approach to study microbes. Rather than isolating ... directly to environmental samples to obtain information about the ... habitat studied. The ocean is an ideal subject of ... equals that of all other living organisms on earth ...
... Representatives from the Midlands Consortium say they are ... has been chosen to host a new 1billion ... Midlands Consortium is comprised of the universities of ... all with extensive and complementary energy related research ...
... , Vancouver, B.C. - On Sept. 24, 2007, ... at the UBCM Pine Beetle Conference and will announce ... Beetle Program to help affected communities. Location: ... Canada Place Way, Vancouver, B.C. Date and ...
Cached Biology News:Metagenomics of the deep Mediterranean 2Midlands Consortium delighted to be chosen to host £1 billion energy institute 2Midlands Consortium delighted to be chosen to host £1 billion energy institute 3
(Date:7/22/2014)... The DNA Spectrum Ancestry ... representation of history, migration, and culture. , Throughout ... family history stories stemming from Europe. His father passionately ... Pictures and 8mm home movies painted an elaborate picture ... and Steve ordered a test from DNA Spectrum to ...
(Date:7/22/2014)... SHENZHEN , Kina, 22. juli 2014 /PRNewswire/ ... et datterselskab af BGI, verdens største genomics-organisation, annoncerede ... exome-sekvenseringstjeneste baseret på Complete Genomics brancheførende platform. ... for at levere patenterede sekvenseringsteknologier med 99,999 % ... blev købt af BGI i 2013. Mere end ...
(Date:7/22/2014)... Hussey Copper , a leader in copper manufacturing ... Pullman Regional Hospital,s conversion of more than 1,100 touch ... at a nominal cost.  This reasonably priced surface kills ... within 2 hours of exposure 1 and will aid ... in its facilities. Pullman Regional Hospital, in ...
(Date:7/22/2014)... July 22, 2014 Quorum Review IRB, the ... for large clinical trials called Quick Step™ . The ... to address the research industry’s need for seamless study start-up ... is available for studies planning 50 or more North American ... planned North American site count of 80 or more. Qualifying ...
Breaking Biology Technology:DNA Test from DNA Spectrum Shows Heritage Like a Map of the Past 2DNA Test from DNA Spectrum Shows Heritage Like a Map of the Past 3DNA Test from DNA Spectrum Shows Heritage Like a Map of the Past 4BGI Tech lancerer Human Whole Exome-sekvenseringstjeneste på Complete Genomics avancerede platform 2Pullman Regional Hospital changes more than 1,100 touch points to Hussey Copper's MD-Cu29 antimicrobial copper to help protect against bacteria 2Pullman Regional Hospital changes more than 1,100 touch points to Hussey Copper's MD-Cu29 antimicrobial copper to help protect against bacteria 3Quorum Review IRB Launches New Quick Step™ Service for Large Clinical Trials 2Quorum Review IRB Launches New Quick Step™ Service for Large Clinical Trials 3
... Inc., a leader in material science and polymer extrusions, ... The standard was developed by The Society for Automotive ... This certification is merely one indication of Zeus, increased ... working directly with more suppliers to design end products ...
... study, entitled Sustainable Value in Automobile Manufacturing, looks ... manufacturers worldwide between 1999 and 2007. It has ... School in Belfast, in partnership with researchers from ... for Futures Studies and Technology Assessment (IZT) in ...
... CAMBRIDGE, Mass., Oct. 29 Idenix Pharmaceuticals, Inc. (Nasdaq: ... discovery and development of drugs for the treatment of ... has decided not to exercise its option to license ... for the treatment of HCV. As a result, ...
Cached Biology Technology:Zeus Increases Its Presence in Aerospace Industry with AS9100 Certification 2North America automobile sector bottom of 'world sustainability league' 2North America automobile sector bottom of 'world sustainability league' 3Idenix Retains Worldwide Rights to Develop and Commercialize IDX184 for the Treatment of HCV 2Idenix Retains Worldwide Rights to Develop and Commercialize IDX184 for the Treatment of HCV 3
BD BioCoat Matrigel Matrix 35 mm Culture Dishes Coating : BD MatrigelTM Basement Membrane Matrix ,Surface : ECM/attachment factors ,Surface area : 9.6 cm2 ,Dim nominal : 35 mm x 10 mm ,Vo...
BD BioCoat Fibronectin 35 mm Culture Dishes, tissue-culture treated polystyrene with a uniform application of human fibronectin....
... to Human Cytokeratin TYPE II Reacts ... keratins. Including epidermal cell keratin of 86 ... and 67kD. Broad keratin reactivity is found ... Immunogen: Human epidermal ...
BD BioCoat Fibronectin 150 mm Culture Dishes...
Biology Products: