MNI researchers locate neurological basis of depression following sports ...(howed reduced brain activity in regions ...)

Date:1/18/2008

howed reduced brain activity in regions known to be implicated in depression, specifically, the dorsolateral prefrontal cortex and striatum and attenuated deactivation in medial frontal and temporal regions. We discovered that concussed subjects with depression presented with the same pattern of brain activation as that seen for patients with major depression.

Other studies have shown a link between a history of brain injury and probability of developing major depression later in life. Therefore understanding the pathology of depression in concussed subjects has important implications for early intervention and successful outcomes.

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Contact: Anita Kar anita.kar@mcgill.ca 514-398-3376 Montreal Neurological Institute and Hospital Source:Eurekalert

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