Navigation Links
MIT works toward engineered blood vessels
Date:12/17/2007

CAMBRIDGE, Mass.-MIT scientists have found a way to induce cells to form parallel tube-like structures that could one day serve as tiny engineered blood vessels.

The researchers found that they can control the cells' development by growing them on a surface with nano-scale patterning. A paper on the work was posted this month in an online issue of Advanced Materials.

Engineered blood vessels could one day be transplanted into tissues such as the kidneys, liver, heart or any other organs that require large amounts of vascular tissue, which moves nutrients, gases and waste to and from cells.

"We are very excited about this work, said Robert Langer, MIT Institute Professor and an author of the paper. It provides a new way to create nano-based systems with what we hope will provide a novel way to someday engineer tissues in the human body.

The work focuses on vascular tissue, which includes capillaries, the tiniest blood vessels, and is an important part of the circulatory system. The team has created a surface that can serve as a template to grow capillary tubes aligned in a specific direction.

The researchers built their template using microfabrication machinery at Draper Laboratory in Cambridge. Normally such technology is used to build micro-scale devices, but the researchers adapted it to create nano-scale patterns on a silicone elastomer substrate. The surface is patterned with ridges and grooves that guide the cells' growth.

The cells can sense (the patterns), and they end up elongated in the direction of those grooves, said Christopher Bettinger, MIT graduate student in materials science and engineering and lead author of the paper.

The cells, known as endothelial progenitor cells (EPCs), not only elongate in the direction of the grooves, but also align themselves along the grooves. That results in a multicellular structure with defined edges, also called a band structure.

Once the ba
'/>"/>

Contact: Elizabeth Thomson
thomson@mit.edu
617-258-5402
Massachusetts Institute of Technology
Source:Eurekalert

Page: 1 2

Related biology news :

1. Rain forest protection works in Peru
2. MIT works toward safer gene therapy
3. IdentiPHI Re Launches SAFmodule Software to Secure Novell(R) Networks
4. IdentiPHI Re Launches SAFmodule Software to Secure Novell(R) Networks
5. Alternative food networks connect ethical producers and consumers and can lead to healthier eating
6. Workshops on biotechnology and water for science journalists
7. Bursts of waves drive immune system soldiers toward invaders
8. A step toward tissue-engineered heart structures for children
9. Research points towards early cancer detection
10. Researchers take first steps towards spinal cord reconstruction following injury
11. Fish farms drive wild salmon populations toward extinction
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... , Europe,s most prestigious ... Office to present a video retrospective of the most exciting and ... Christofer Toumazou and Sophie Wilson   A ... Award   Starting on 22 January 2015 on   http://www.epo.org/european-inventor ...
(Date:1/22/2015)... , Jan. 22, 2015 Infinisource has launched its ... the G2 model. The G2 sets a higher standard for ... human capital management solution. With plug-and-play installation, touch screen interface ... clock provides a robust time collection solution for the small ...
(Date:12/22/2014)... Dec. 22, 2014 Research and Markets ... the "The Global Watermarking and Fingerprinting Markets" ... http://photos.prnewswire.com/prnh/20130307/600769 This insight ... watermarking and fingerprinting markets. Watermarking aims to control ...
Breaking Biology News(10 mins):Ten Years of the European Inventor Award: A Retrospective Look at the Inventors and Ideas That Have Changed Our Lives 2Ten Years of the European Inventor Award: A Retrospective Look at the Inventors and Ideas That Have Changed Our Lives 3Infinisource's NXG series sets new time clock standard 2The Global Watermarking and Fingerprinting Markets 2
... live in a pond, a grassland, a mountain range or ... Hence the wide range of estimates for the planet,s biodiversity, ... A new way of estimating species richness reported this ... of California, Berkeley, ecologist John Harte and colleagues, will make ...
... Calif.) Coastal marine ecosystems are at risk worldwide as ... Santa Barbara who have recently published a study in the ... the first integrated analysis of all coastal areas of the ... address a litany of impacts from human activities, from the ...
... Through a recent modeling experiment, a team of NASA-funded researchers ... in the atmosphere and of nitrogen in the soil are ... cycling of water from sky to land to waterways. ... be underestimating how much water is likely to run off ...
Cached Biology News:New theory gives more precise estimates of large-scale biodiversity 2New theory gives more precise estimates of large-scale biodiversity 3New study ranks 'hotspots' of human impact on coastal areas 2Ozone, nitrogen change the way rising CO2 affects Earth's water 2Ozone, nitrogen change the way rising CO2 affects Earth's water 3
(Date:12/24/2014)... 2014 “Preparative & Process Chromatography ... Consumables (Columns, Solvents, Buffers, Valves, Guages, Seals), Accessories, ... - Forecasts to 2019” provides a detailed overview ... market trends, and strategies impacting the preparative and ...
(Date:12/24/2014)... 23, 2014 Earlier this year in a ... of the Adult Stem Cell Technology Center, LLC ( ASCTC ... unique property of adult tissue stem cells. His title ... Important for the Future,” embodied the essence of his message ...
(Date:12/24/2014)... On Friday, December 19, 2014, President ... Continuing Resolution Appropriations Act of 2015, which for the ... funding through the Congressionally Directed Medical Research Programs (CDMRP) ... Association (HA), working in conjunction with its allies on ...
(Date:12/24/2014)... 2014 The report provides basic ... classification, application and industry overview. This report also ... structure. Production is separated by regions, technology and ... equipment, downstream client survey, marketing channels, industry development ...
Breaking Biology Technology:Preparative and Process Chromatography Market is expected to reach $9 billion by 2019 - New Report by Marketsandmarkets 2Preparative and Process Chromatography Market is expected to reach $9 billion by 2019 - New Report by Marketsandmarkets 3Preparative and Process Chromatography Market is expected to reach $9 billion by 2019 - New Report by Marketsandmarkets 4Adult Stem Cell Technology Center, LLC’s Director Sherley's Address on What’s Holding Back Regenerative Medicine Featured on Omics Group Website 2Adult Stem Cell Technology Center, LLC’s Director Sherley's Address on What’s Holding Back Regenerative Medicine Featured on Omics Group Website 3Adult Stem Cell Technology Center, LLC’s Director Sherley's Address on What’s Holding Back Regenerative Medicine Featured on Omics Group Website 4Rare Brain Condition Now Eligible for Department of Defense Research Dollars 2Worldwide Methyl Mercaptan Market 2015-2020 Forecasts on Development & Trends Now Available at ReportsnReports.com 2
... Small Interfering RNAs (siRNAs) are , ... mRNAs for degradation via a cellular process termed RNA interference , ... publications have described , the use ... knockdown studies (for a review, see Tuschl, 2002). Two different , ...
... Now it's easy to make your ... and ready for RT-PCR. DNA- free DNase Treatment , ... DNase digestion buffer, to ensure safe, complete removal of , ... a unique , DNase Removal Reagent which, ...
... , ... RT-PCR and microarray gene expression analysis , ... minutes: no grinding or polytron required , ... in tissue lysates , Faster and ...
Cached Biology Technology:More siRNA Vectors for RNA Interference 2More siRNA Vectors for RNA Interference 3More siRNA Vectors for RNA Interference 4More siRNA Vectors for RNA Interference 5More siRNA Vectors for RNA Interference 6More siRNA Vectors for RNA Interference 7DNA-free A NEW Method to Remove DNA 2DNA-free A NEW Method to Remove DNA 3DNA-free A NEW Method to Remove DNA 4DNA-free A NEW Method to Remove DNA 5DNA-free A NEW Method to Remove DNA 6DNA-free A NEW Method to Remove DNA 7DNA-free A NEW Method to Remove DNA 8Hands-free Tissue Disruption No Homogenization Needed 2Hands-free Tissue Disruption No Homogenization Needed 3Hands-free Tissue Disruption No Homogenization Needed 4Hands-free Tissue Disruption No Homogenization Needed 5Hands-free Tissue Disruption No Homogenization Needed 6Hands-free Tissue Disruption No Homogenization Needed 7
Request Info...
Anti-Bcl-G (CT) Host: rabbit polyclonal Species Reactivity: human, mouse, rat Applications: WB, IHC Storage: 4C...
Polyclonal antiserum raised against conjugated L-isoleucine. Available as antiserum. Amino Acid Antibodies...
Mouse monoclonal [002-49] to C1s ( Abpromise for all tested applications). entrezGeneID: 716 SwissProtID: P09871...
Biology Products: