Navigation Links
MIT researchers reveal how the brain keeps eyes on the prize
Date:8/4/2013

Cambridge-- As anyone who has traveled with young children knows, maintaining focus on distant goals can be a challenge. A new study from MIT suggests how the brain achieves this task, and indicates that the neurotransmitter dopamine may signal the value of long-term rewards. The findings may also explain why patients with Parkinson's disease in which dopamine signaling is impaired often have difficulty in sustaining motivation to finish tasks.

The work is described this week in the journal Nature.

Previous studies have linked dopamine to rewards, and have shown that dopamine neurons show brief bursts of activity when animals receive an unexpected reward. These dopamine signals are believed to be important for reinforcement learning, the process by which an animal learns to perform actions that lead to reward.

Taking the long view

In most studies, that reward has been delivered within a few seconds. In real life, though, gratification is not always immediate: Animals must often travel in search of food, and must maintain motivation for a distant goal while also responding to more immediate cues. The same is true for humans: A driver on a long road trip must remain focused on reaching a final destination while also reacting to traffic, stopping for snacks, and entertaining children in the back seat.

The MIT team, led by Institute Professor Ann Graybiel who is also an investigator at MIT's McGovern Institute for Brain Research decided to study how dopamine changes during a maze task approximating work for delayed gratification. The researchers trained rats to navigate a maze to reach a reward. During each trial a rat would hear a tone instructing it to turn either right or left at an intersection to find a chocolate milk reward.

Rather than simply measuring the activity of dopamine-containing neurons, the MIT researchers wanted to measure how much dopamine was released in the striatum, a brai
'/>"/>

Contact: Kimberly Allen
allenkc@mit.edu
617-253-2702
Massachusetts Institute of Technology
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Mount Sinai researchers develop first successful laboratory model for studying hepatitis C
2. Montana State University researchers highlight bears use of Banff highway crossings
3. HudsonAlpha and UAB researchers work to identify optimal treatments for ER+ breast cancer
4. UPCI researchers target cell sleep to lower chances of cancer recurrence
5. U-M researchers land $2M grant to cooperate with nature on growing algae for energy
6. UT Southwestern researchers identify novel mechanism that helps stomach bug cause illness
7. Researchers uncover cellular mechanisms for attention in the brain
8. Notre Dame researchers develop system that uses a big data approach to personalized healthcare
9. U of M researchers unveil nations first porcine virus rapid detection test
10. Researchers reveal the clearest new pictures of immune cells
11. Researchers describe potential for MERS coronavirus to spread internationally
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/14/2015)... YORK , April 14, 2015  HYPR ... IDentity Online (FIDO ® ) Alliance tm , ... specifications. FIDO members commit to share technology and ... methods that are interoperable, more secure and private, ... enable biometric identity verification that protects sensitive user ...
(Date:4/13/2015)... 2015 According to a ... Market Forecast & Opportunities, 2020", the global biometrics market ... 14% till 2020. The biometrics market is garnering ... and review of biometric management systems. The constant ... with greater efficiency, are resulting in increasing installation ...
(Date:4/10/2015)... Research and Markets ( http://www.researchandmarkets.com/research/cjk4gb/security ) has ... - NEC" report to their offering. ... to supply a range of IT security management and ... on the development of a Big Data and cloud ... Asia-Pacific region is a core ...
Breaking Biology News(10 mins):HYPR Corp. Joins the FIDO Alliance 2HYPR Corp. Joins the FIDO Alliance 3Global Biometrics Market to Cross US$ 21 Billion by 2020: TechSci Research 2NEC Security Competitive Profile 2015 2
... As the desert Southwest becomes hotter and drier, ... dominated by mesquite trees, such as Prosopis velutina, and ... researchers has found. In a "leaf-to-landscape" approach, the ... across entire ecosystems to quantify how well grasslands, compared ...
... Bonheur Professor Russell Chesney, M.D. believes he knows what was ... Christmas Carol." Based on detailed descriptions of both the ... hypothesizes that Tiny Tim suffered from a combination of rickets ... March 5 edition of Archives of Pediatrics and Adolescent ...
... now 20 years old, and its network of protected areas, known ... start, the network now includes some 26 000 protected sites and ... significant areas of sea. It is widely considered to be the ... criteria. The review has been published in the newly ...
Cached Biology News:Mesquite trees displacing Southwestern grasslands 2Mesquite trees displacing Southwestern grasslands 3Mesquite trees displacing Southwestern grasslands 4Mesquite trees displacing Southwestern grasslands 5Building the European Union's Natura 2000 -- the largest ever network of protected areas 2
(Date:5/20/2015)... 20, 2015 Research and Markets ( ... "Top Technologies in HW_Technical Insights" report to their ... evaluated technology trends in the Health and Wellness sector ... to have an impact in the year 2015. The ... top 10 health and wellness technologies that are anticipated ...
(Date:5/20/2015)... , May 20, 2015  Select Medical ... the Federal Trade Commission granted early termination of ... Improvements Act of 1976, as amended, applicable to ... Acquisition Corporation, a joint venture that Select has ... As previously announced, MJ Acquisition Corporation ...
(Date:5/20/2015)... 20, 2015 Agricultural firm H.J. Baker ... its acquisition of Tiger-Sul. Since the purchase of ... Canada) in May 2005, H.J. Baker has leveraged the ... into a comprehensive portfolio of product offerings and solutions ... Baker and the innovation of Tiger-Sul, transforming the company ...
(Date:5/20/2015)... , May 20, 2015  Cypher Genomics, ... a collaboration with Celgene Corporation to apply Cypher,s ... biomarkers that associate with patient response to innovative ... intended to help accelerate patient access to the ... in clinical research and development and potentially inform ...
Breaking Biology Technology:Top Technologies in the Health and Wellness Industry 2015 2Select Medical Corporation's Proposed Acquisition of Concentra Inc. through Joint Venture with Welsh Carson Receives Antitrust Clearance 2Agricultural Firm H.J. Baker & Bro., Inc., Celebrates 10 Years Since Acquisition Of Tiger-Sul 2Agricultural Firm H.J. Baker & Bro., Inc., Celebrates 10 Years Since Acquisition Of Tiger-Sul 3Cypher Genomics Collaborates with Celgene Corporation to Identify Novel Genomic Biomarkers 2
... , SAN DIEGO, Nov. 24, 2009 Arena Pharmaceuticals, ... company is scheduled to present at the Piper Jaffray 21st Annual ... Time (8:30 a.m. Pacific Time) at the New York Palace Hotel ... Officer, is scheduled to provide an overview of the company, including ...
... , BOZEN, Italy, ... formed a new Canadian joint venture with a group ... under the,name Health Robotics Canada, Inc. and will market, ... concept, which includes the,revolutionary product offerings i.v.STATION(TM), i.v.SOFT(TM), and ...
... ... Abstracts Service (CAS), the global expert on chemical information, reports that China,s ... in chemistry. China trailed Japan,s patent office, the World Intellectual Property Organization ... than a decade, but passed the USPTO in 2005, WIPO in 2006, ...
Cached Biology Technology:Arena Pharmaceuticals to Present at the Piper Jaffray 21st Annual Health Care Conference 2Arena Pharmaceuticals to Present at the Piper Jaffray 21st Annual Health Care Conference 3Health Robotics Continues its Global Expansion With December 09 ASHP's Launch of Joint Venture in Canada 2Health Robotics Continues its Global Expansion With December 09 ASHP's Launch of Joint Venture in Canada 3China Leads All Nations in Publication of Chemical Patents According to CAS, the World's Most Authoritative Publisher of Chemical Information 2China Leads All Nations in Publication of Chemical Patents According to CAS, the World's Most Authoritative Publisher of Chemical Information 3
Mouse monoclonal [6911] to E. coli K99 pilus ( Abpromise for all tested applications)....
...
... HyPer is the first fully genetically ... detection of intracellular hydrogen peroxide (H2O2), one ... Developed on the basis of yellow fluorescent ... Escherichia coli protein OxyR (OxyR-RD), HyPer demonstrates ...
Alexa Fluor 647 anti-mouse Qa-2...
Biology Products: