Navigation Links
MIT researchers offer glimpse of rare mutant cells
Date:7/21/2008

So was developing a new type of microscopy, known as two-photon imaging, and the researchers wondered whether it could be used to locate and image rare types of cells.

The team genetically engineered a strain of mice in which DNA would fluoresce if a mutation occurred in a particular sequence. That allowed them to use So's newly developed high-resolution, high-throughput microscopy technique to detect individual cells that carry the mutation.

"The problem drove the development of a new imaging technology, which now can be used for lots of things," said Engelward.

Lead author of the paper is Dominika Wiktor-Brown, a postdoctoral associate in biological engineering. Other authors of the paper are Hyuk-Sang Kwon, a research affiliate in the Department of Mechanical Engineering, and Yoon Sung Nam, a graduate student in biological engineering.

The work was truly a team effort between many people with very different areas of expertise, said Engelward. "The Department of Biological Engineering and the Center for Environmental Health Sciences are key in helping to bridge people across disciplines," she said.


'/>"/>

Contact: Teresa Herbert
therbert@mit.edu
617-258-5403
Massachusetts Institute of Technology
Source:Eurekalert

Page: 1 2

Related biology news :

1. UC San Diego researchers could help US military thwart explosive threats
2. As rates rise, researchers find better way to identify melanoma
3. Researchers discover a gene that regulates and blocks ovulation
4. Researchers discover link between organ transplantation and increased cancer risk
5. Dartmouth researchers discover gene signatures for scleroderma
6. Louisiana Tech researchers feature drug reformulation in prestigious journal
7. UCLA researchers locate and image prostate cancer as it spreads to lymph nodes
8. Researchers catch ion channels in their opening act
9. UGA researchers discover mechanism that explains how cancer enzyme winds up on ends of chromosomes
10. Researchers hack final part of the immune system code
11. Iowa State researchers study ground cover to reduce impact of biomass harvest
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/3/2015)... , Aug. 3, 2015 Synaptics, Inc. ... interface solutions, today announced that members of the executive ... the Pacific Crest Global Technology Leadership Forum on Tuesday, ... conference will be held at the Sonnenalp Resort in ... The presentation may include forward-looking information. An audio webcast ...
(Date:7/31/2015)... , Chine, 31 juillet 2015 La ... www.icg-10.org ) sera organisée par le BGI du ... Shenzhen en Chine. La ... son inauguration en 2006, l,ICG est devenue l,une ... le domaine des « omiques » et c,est aussi la ...
(Date:7/31/2015)... 31, 2015 The 10 th International Conference ... BGI from October 22-25, 2015, in Shenzhen , ... is celebrating its 10 th anniversary this year. Since its ... most influential annual meetings in the ,omics, fields, and is ... ICG-10 focuses on recent breakthroughs and advances ...
Breaking Biology News(10 mins):La 10e International Conference on Genomics (ICG-10) doit s'ouvrir en octobre 2La 10e International Conference on Genomics (ICG-10) doit s'ouvrir en octobre 3The 10th International Conference on Genomics (ICG-10) to Open in October 2
... N.Y. (Tuesday, April 1, 2008) Identifying genes ... the mouse used to be a monumental task. ... it effective for even the smallest laboratories. This ... ( www.cshprotocols.org/TOCs/toc4_08.dtl ) highlights a method for screening the ...
... Challenges and Promise of Cell-Based Therapies is ... medicine using stem cells. The opening plenary session will ... will be followed by four plenary sessions that will ... musculoskeletal, and metabolic diseases and disorders. It will close ...
... 2008Biotechnology companies are focusing on the development of ... diagnostic tests for cancer, reports Genetic Engineering and ... forward, a much stronger and targeted emphasis on ... in the April 1 issue of GEN ( ...
Cached Biology News:Cold Spring Harbor Protocols features methods to screen genomes and analyze evolution 2Challenges and promise of cell-based therapies 2
(Date:8/26/2015)... Aug. 26, 2015  The Diabetes Research Institute ... of Miami Miller School of Medicine, announced today ... to test for the first time a novel ... This FDA approved Phase I/II study builds upon ... is an important first step toward the development ...
(Date:8/26/2015)... 26, 2015 Intrexon Corporation (NYSE: XON ... closing of its previously announced public offering of common ... of their option to purchase an additional 731,707 shares ... $41.00 per share.  The exercise of the underwriters, option ... sold by Intrexon to 5,609,756 shares and increased the ...
(Date:8/26/2015)... 2015 China Cord Blood Corporation (NYSE: ... leading provider of cord blood collection, laboratory testing, hematopoietic ... announced that the Company has been informed that Magnum ... owned by Mr. Yuen Kam, chairman of the board ... shares (the "Shares") of  Excellent China Healthcare Investment Limited ...
(Date:8/26/2015)... August 26, 2015 Despite ... fueling the optimism in biotech,s forecast is the ... life sciences advancements.  Active biotechnology & healthcare companies ... Inc. (OTCQB: PBIO), Sequenom, Inc. (NASDAQ: SQNM ... Raptor Pharmaceutical Corp. (NASDAQ: RPTP ) and ...
Breaking Biology Technology:Diabetes Research Institute Successfully Transplants First Patient In Pilot BioHub Trial 2Diabetes Research Institute Successfully Transplants First Patient In Pilot BioHub Trial 3Diabetes Research Institute Successfully Transplants First Patient In Pilot BioHub Trial 4Intrexon Announces Closing of $230 Million Public Offering of Common Stock including Full Exercise of Underwriters' Option to Purchase Additional Shares 2Intrexon Announces Closing of $230 Million Public Offering of Common Stock including Full Exercise of Underwriters' Option to Purchase Additional Shares 3Intrexon Announces Closing of $230 Million Public Offering of Common Stock including Full Exercise of Underwriters' Option to Purchase Additional Shares 4China Cord Blood Corporation Receives Notice of Transactions Regarding its 7% Senior Convertible Notes Due 2017 2China Cord Blood Corporation Receives Notice of Transactions Regarding its 7% Senior Convertible Notes Due 2017 3New Collaborations & Mergers For Research of Molecular Biomarkers in Human Diseases & Clinical Trials for Cancer Therapies Fueling Growth in Multi-Billion Dollar Life Sciences Market 2New Collaborations & Mergers For Research of Molecular Biomarkers in Human Diseases & Clinical Trials for Cancer Therapies Fueling Growth in Multi-Billion Dollar Life Sciences Market 3New Collaborations & Mergers For Research of Molecular Biomarkers in Human Diseases & Clinical Trials for Cancer Therapies Fueling Growth in Multi-Billion Dollar Life Sciences Market 4New Collaborations & Mergers For Research of Molecular Biomarkers in Human Diseases & Clinical Trials for Cancer Therapies Fueling Growth in Multi-Billion Dollar Life Sciences Market 5New Collaborations & Mergers For Research of Molecular Biomarkers in Human Diseases & Clinical Trials for Cancer Therapies Fueling Growth in Multi-Billion Dollar Life Sciences Market 6New Collaborations & Mergers For Research of Molecular Biomarkers in Human Diseases & Clinical Trials for Cancer Therapies Fueling Growth in Multi-Billion Dollar Life Sciences Market 7
... Alfacell Corporation,(Nasdaq: ACEL ) today reported its financial ... 31, 2008., The company recorded a net loss ... common share, for the fourth fiscal quarter ended,July 31, ... or $0.05 per,basic and diluted common share, for the ...
... Oct. 14 /Xinhua-PRNewswire-FirstCall/ -- China Sky One,Medical, Inc. ... CSKI ), a,leading fully integrated pharmaceutical company ... ("PRC"), announced today that it,started production at Peng ... that it acquired, on October 14, 2008., ...
... and facilitate new R&D,collaborations-, WASHINGTON, Oct. 14 ... that the Bill & Melinda Gates Foundation has,expanded ... further engage,biotechnology industry innovation to create new medicines ... million grant will help BVGH build,the market case ...
Cached Biology Technology:Alfacell Reports Fiscal Fourth Quarter and Full Year 2008 Financial Results 2Alfacell Reports Fiscal Fourth Quarter and Full Year 2008 Financial Results 3Alfacell Reports Fiscal Fourth Quarter and Full Year 2008 Financial Results 4Alfacell Reports Fiscal Fourth Quarter and Full Year 2008 Financial Results 5China Sky One Medical, Inc. Starts Production at Newly Acquired Facility and Reaffirms Guidance 2China Sky One Medical, Inc. Starts Production at Newly Acquired Facility and Reaffirms Guidance 3BIO Ventures for Global Health Receives $7 Million Grant from Gates Foundation to Engage Biotechnology in the Fight Against Neglected Diseases of the Developing World 2
Request Info...
... FLA-7000 excels at fluorescent and radioisotopic image ... features four easy-to-access filters (filters of Y520, ... Imaging Plates) for upgrading flexibility. In addition, ... four kinds of excitation laser beams. ,The ...
... Labeling Kit generates labeled cDNA for use ... is made via a reverse transcription from ... Unlike other methods, there are no unnatural ... reaction. This unmodified cDNA is then labeled ...
... An easy-to-use solution that enables fully automated ... 400 Hybridization Station has been designed to ... the throughput necessary to perform a wide ... performed in the range 485C; denaturations of ...
Biology Products: