Navigation Links
MIT crafts bacteria-resistant films
Date:5/15/2008

CAMBRIDGE, Mass.--Having found that whether bacteria stick to surfaces depends partly on how stiff those surfaces are, MIT engineers have created ultrathin films made of polymers that could be applied to medical devices and other surfaces to control microbe accumulation.

The inexpensive, easy-to-produce films could provide a valuable layer of protection for the health care industry by helping to reduce the spread of hospital-acquired infections, which take the lives of 100,000 people and cost the United States an estimated $4.5 billion annually.

The researchers, who describe their work in an upcoming issue of the journal Biomacromolecules, found they could control the extent of bacterial adhesion to surfaces by manipulating the mechanical stiffness of polymer films called polyelectrolyte multilayers. Thus, the films could be designed to prevent accumulation of hazardous bacteria or promote growth of desirable bacteria.

All other factors being equal, mechanical stiffness of material surfaces increases bacterial adhesion, said Krystyn Van Vliet, the Thomas Lord Assistant Professor of Materials Science and Engineering and the paper's anchor author.

Van Vliet and her colleagues found the same trend in experiments with three strains of bacteria: Staphylococcus epidermidis, commonly found on skin, and two types of Escherichia coli.

Stiffness has usually been overlooked in studies of how bacteria adhere to surfaces in favor of other traits such as surface charge, roughness, and attraction to or repulsion from water. The new work shows that stiffness should also be taken into account, said Van Vliet.

The new films could be combined with current methods of repelling bacteria to boost their effectiveness, said Michael Rubner, an author of the paper and director of MIT's Center for Materials Science and Engineering.

Those methods include coating surfaces with antimicrobial chemicals or embedding metal nanopart
'/>"/>

Contact: Elizabeth Thomson
thomson@mit.edu
617-258-5402
Massachusetts Institute of Technology
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Turning on cell-cell communication wipes out staph biofilms
2. Microbial biofilms evoke Jekyll & Hyde effects
3. Films of Mitchell and Kenyon illuminate lefties decline in Victorian England
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/24/2014)... Allan, PhD, a scientist at Western University and the ... spreads or metastasizes to the lung. , Breast cancer ... two cause of cancer-related deaths among women in North ... have a high success rate, but once the disease ... particular, the lung is one of the most common ...
(Date:4/24/2014)... at Ludwig-Maximilians-Universitaet (LMU) in Munich have identified the ... to discriminate between viral and endogenous RNAs in ... take control of cellular metabolism and hijack cellular ... process is dependent on viral RNA molecules that ... RNA viruses) and/or newly synthesized in the host ...
(Date:4/24/2014)... be improved with new insights into the make-up of ... the Amazon Basin have revealed unprecedented detail of the ... by comparing satellite maps with hundreds of field plots. ... more accurately the amount of carbon each tree can ... schemes, in which trees are given a cash value ...
Breaking Biology News(10 mins):New study helps to explain why breast cancer often spreads to the lung 2Viral infections: Identifying the tell-tale patterns 2Viral infections: Identifying the tell-tale patterns 3Amazon rainforest survey could improve carbon offset schemes 2
... states are invited to attend the annual meeting of ... Oct. 28 and 29 in Spokane, Wash. The ... policy and technology of carbon capture and storage (CCS). ... carbon sequestration technologies, the economics of CCS, regulatory and ...
... Zeitlinger, Ph.D., Stowers Institute Assistant Investigator, has been ... National Institutes of Health (NIH). Dr. Zeitlinger was ... million over five years. The awards enable recipients ... biomedical and behavioral science. "Nothing is ...
... assistant bioengineering professor at the UC San Diego Jacobs School ... tissue engineering. With a new $1.5 million New Innovator Award ... be able to do just that. , The awards, ... small number of new investigators who have exceptional creativity and ...
Cached Biology News:Julia Zeitlinger selected for NIH Director's New Innovator Award 2Generation innovation: Young UC San Diego bioengineer to use NIH grant to fuel tissue engineering 2Generation innovation: Young UC San Diego bioengineer to use NIH grant to fuel tissue engineering 3
(Date:1/14/2014)... 14, 2014 The largest international professional organization ... and therapeutic derivatives thereof has endorsed an educational ... about the challenges of adulterated herb and botanical ... The Society for Medicinal Plant and ...
(Date:1/14/2014)... 14, 2014 In recent years, growing ... methods in product development and promotion has led to ... mistrust, fueled by concerns about the insidious impact of ... of spectacular fines to the world’s biggest pharmas for ...
(Date:1/14/2014)... 2014   Kinaxis ®, provider of RapidResponse ®, a ... operations planning ( S&OP ) service, is proud to be ... will be held at the Hilton San Diego Bayfront, January ... Elisabeth Kaszas , Director of Supply Chain at Amgen, ...
(Date:1/14/2014)... During the 1600’s through the 1800’s doctors contributed ... In this time period, doctors did not know that they ... the death of vulnerable patients. In the same way, medical ... be unwittingly transmitting herpes viruses to their patients. The CBCD ...
Breaking Biology Technology:World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 2World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 3World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 4World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 5World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 6World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 7World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 8The Sunshine Act: Necessary Regulation or Unnecessary Dysregulation? New Life Science Webinar Hosted by Xtalks and IRB Services 2The Sunshine Act: Necessary Regulation or Unnecessary Dysregulation? New Life Science Webinar Hosted by Xtalks and IRB Services 3Event Alert: Kinaxis Customer to Present at the Biomanufacturing Summit "Supply Chain: Improving Network Effectiveness" 2Study: Fatigued Medical Interns Infect Their Patients with Herpes Viruses; The CBCD Sees a Parallel with “The Doctor’s Plague” 2Study: Fatigued Medical Interns Infect Their Patients with Herpes Viruses; The CBCD Sees a Parallel with “The Doctor’s Plague” 3
... May 19 /PRNewswire-FirstCall/ - Angiotech Pharmaceuticals, Inc. (NASDAQ: ... Quill(TM) SRS wound closure product line is now available ... at https://ecommerce.angiotech.com/Main/Home.aspx . The Quill SRS products are ... Polydioxanone (PDO), MONODERM(TM), Nylon and Polypropylene product lines. , ...
... with Novel Mode of ActionMOUNTAIN VIEW, Calif., May ... that data from the company,s PROTECT-1 (the Prospective ... Phase II/III clinical trial of Traficet-EN(TM) (CCX282-B) in ... in an oral session at the upcoming 2009 ...
... -- Leading pharmaceutical and biotech,companies are drawing on ... enhance their R&D productivity, leverage academic,insights and diversify ... a population,base that is representative of key Asian ... companies to test and develop new solutions for,Asia ...
Cached Biology Technology:Angiotech launches e-commerce website that allows customers to order Quill(TM) SRS product line 2Angiotech launches e-commerce website that allows customers to order Quill(TM) SRS product line 3Angiotech launches e-commerce website that allows customers to order Quill(TM) SRS product line 4ChemoCentryx's Traficet-EN(TM) Phase II/III Induction Phase Data in Crohn's Disease to be Featured in Oral Presentation at 2009 Digestive Disease Week 2ChemoCentryx's Traficet-EN(TM) Phase II/III Induction Phase Data in Crohn's Disease to be Featured in Oral Presentation at 2009 Digestive Disease Week 3ChemoCentryx's Traficet-EN(TM) Phase II/III Induction Phase Data in Crohn's Disease to be Featured in Oral Presentation at 2009 Digestive Disease Week 4ChemoCentryx's Traficet-EN(TM) Phase II/III Induction Phase Data in Crohn's Disease to be Featured in Oral Presentation at 2009 Digestive Disease Week 5Pharma and Biotech Companies Plug into Singapore's Integrated Research Network 2Pharma and Biotech Companies Plug into Singapore's Integrated Research Network 3Pharma and Biotech Companies Plug into Singapore's Integrated Research Network 4Pharma and Biotech Companies Plug into Singapore's Integrated Research Network 5
... Immunogen KLH-conjugated, synthetic ... 54-75 (RRGPHRNPG-PGDDDGQRSRSSS) of mouse p19ARF. ... to amino acids 62-75. Clone ... Routinely evaluated by immunoblot. ...
Request Info...
Hybridization cassette for one slide...
Request Info...
Biology Products: