Navigation Links
MIT: Mimicking the brain, in silicon
Date:11/15/2011

h biological systems. This could be useful in enabling communication between neural prosthetic devices such as artificial retinas and the brain. Further down the road, these chips could also become building blocks for artificial intelligence devices, Poon says.

Debate resolved

The MIT researchers have already used their chip to propose a resolution to a longstanding debate over how LTD occurs.

One theory holds that LTD and LTP depend on the frequency of action potentials stimulated in the postsynaptic cell, while a more recent theory suggests that they depend on the timing of the action potentials' arrival at the synapse.

Both require the involvement of ion channels known as NMDA receptors, which detect postsynaptic activation. Recently, it has been theorized that both models could be unified if there were a second type of receptor involved in detecting that activity. One candidate for that second receptor is the endo-cannabinoid receptor.

Endo-cannabinoids, similar in structure to marijuana, are produced in the brain and are involved in many functions, including appetite, pain sensation and memory. Some neuroscientists had theorized that endo-cannabinoids produced in the postsynaptic cell are released into the synapse, where they activate presynaptic endo-cannabinoid receptors. If NMDA receptors are active at the same time, LTD occurs.

When the researchers included on their chip transistors that model endo-cannabinoid receptors, they were able to accurately simulate both LTD and LTP. Although previous experiments supported this theory, until now, "nobody had put all this together and demonstrated computationally that indeed this works, and this is how it works," Poon says.


'/>"/>

Contact: Caroline McCall
cmccall5@mit.edu
Massachusetts Institute of Technology
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Some vocal-mimicking animals, particularly parrots, can move to a musical beat
2. Wildlife Conservation Society finds wild cat mimicking monkey calls
3. Boston Univ., Veterans Affairs find sports brain trauma may cause disease mimicking ALS
4. Mimicking nature, water-based artificial leaf produces electricity
5. Mimicking nature at the nanoscale: Selective transport across a biomimetic nanopore
6. Changing fine structure constant, packing spheres tighter, and mimicking complex birdsongs
7. Social interactions can alter gene expression in the brain, and vice versa
8. Knee injuries may start with strain on the brain, not the muscles
9. Experimental drug shows promise against brain, prostate cancers
10. UR study reveals chemos toxicity to brain, possible treatment
11. Regular aerobic exercise is good for the brain, Pitt team says
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2014)... by the National Science Foundation (NSF), counters a ... atmospheric warming, indicating instead that certain Arctic lakes ... the atmosphere. , The study, published this ... on thermokarst lakes, which occur as permafrost thaws ... fresh water, converting what was previously frozen land ...
(Date:7/31/2014)... biomass burning burning forests to create agricultural ... agriculture and wildfires figures into both climate ... release of a new study by Stanford University ... the degree of that contribution had never been ... paper published July 30 in the Journal ...
(Date:7/31/2014)... the roughly 156,000 gas stations across the United ... of underground gas storage tankscorrosion that could result ... source of drinking water. In recent years, field ... corroding gas storage tank components such as sump ... of gasoline-ethanol blends and the presence of bacteria, ...
Breaking Biology News(10 mins):Certain Arctic lakes store more greenhouse gases than they release 2Stanford professor finds that wildfires and other burns play bigger role in climate change 2Stanford professor finds that wildfires and other burns play bigger role in climate change 3Stanford professor finds that wildfires and other burns play bigger role in climate change 4NIST corrosion lab tests suggest need for underground gas tank retrofits 2
... of our daily vocabulary. We all know they,re part of ... We know they have something to do with starches and ... a lot for science to learn about them. ... Nikki Pohl, an Iowa State University associate professor of chemistry. ...
... UC Davis Cancer Center shows that a protein called Muc4 ... spread to other organs and resist therapeutic treatment. The study, ... Research , is one of the first to characterize the ... author of the study, knew that Muc4 was not always ...
... worldwide trade organisation bringing together users and manufacturers of ... Cavimeter was judged by the panel to be "more ... culmination of a period of research, development and exploitation ... Acoustic cavitation is the inception, growth and eventual collapse ...
Cached Biology News:Iowa State chemist synthesizes carbohydrates, launches startup company 2UC Davis researchers identify a protein that may help breast cancer spread, beat cancer drugs 2NPL Cavimeter receives 2009 UIA Outstanding Product Award 2
(Date:7/31/2014)... -- Nearly 20,000 medical professionals and healthcare leaders gathered ... Lab Expo in Chicago from ... research and technology that will advance medicine and get ... Wednesday, July 30, more than 19,500 attendees had registered ... Expo, with more than 10,000 of these attendees coming ...
(Date:7/31/2014)... the sound-processing part of the mouse brain in a ... trees in view. Their imaging technique allows zooming in ... and it enabled the team to watch brain cells ... results, which represent a step toward better understanding how ... the journal Neuron . , In the past, ...
(Date:7/31/2014)... 31, 2014 Rogne Bioscience, a privately-held biotechnology ... , has acquired a licence to anti-inflammatory peptides ... The potent anti-inflammatory activity of the peptides was discovered ... of Oxford,s Sir William Dunn School of ... over $1.5 million in seed financing, is developing a ...
(Date:7/31/2014)... , July 31, 2014 Research ... "Global Genomics Market 2014-2018" report to their ... Genomics is the study of the genetic material ... be a strong basis for the discovery and development ... human diseases or health conditions. Genomics is supported by ...
Breaking Biology Technology:Research on Digital Health, Alzheimer's, Ebola Draws Nearly 20,000 Attendees to 2014 AACC Annual Meeting & Clinical Lab Expo 2Research on Digital Health, Alzheimer's, Ebola Draws Nearly 20,000 Attendees to 2014 AACC Annual Meeting & Clinical Lab Expo 3New mapping approach lets scientists zoom in and out as the brain processes sound 2Oxford licenses anti-inflammatory peptides to San Francisco Bay Area start-up 2Oxford licenses anti-inflammatory peptides to San Francisco Bay Area start-up 3Global Genomics Market 2014-2018: Key Vendors are F. Hoffmann-La Roche, Life Technologies, Qiagen and Illumina 2
... YORK, April 13 NeoStem, Inc. (Amex: ... private placement financing totaling $11 million from three Asia-based ... with strategic investors drawn from leading Asian families and ... per unit, with each unit consisting of one share ...
... Pa., April 10 On April 8th, 2009, Genentech ... marketed by Genentech/Roche and Xoma) from the US market. ... PML associated with Raptiva treatment.BioTrends will field its fourth ... April 13th with a special section dedicated to the ...
... WA, and VANCOUVER, April 9 /PRNewswire-FirstCall/ - OncoGenex Pharmaceuticals, ... ), announced today that it has been named the ... British Columbia. This annual award is presented by LifeSciences ... made outstanding contributions to the development of British Columbia,s ...
Cached Biology Technology:NeoStem Completes $11 Million Private Placement Financing to Support Expansion Activities in China, Further Development of NeoStem's VSEL Technology and Advancement of Medical Tourism Initiatives 2NeoStem Completes $11 Million Private Placement Financing to Support Expansion Activities in China, Further Development of NeoStem's VSEL Technology and Advancement of Medical Tourism Initiatives 3NeoStem Completes $11 Million Private Placement Financing to Support Expansion Activities in China, Further Development of NeoStem's VSEL Technology and Advancement of Medical Tourism Initiatives 4Latest BioTrends Research Reports to Assess the Impact of the Withdrawal of Raptiva (efalizumab) on the Psoriasis Market 2OncoGenex Pharmaceuticals Named Life Sciences Company of the Year by LifeSciences British Columbia 2OncoGenex Pharmaceuticals Named Life Sciences Company of the Year by LifeSciences British Columbia 3