Navigation Links
MIT: Making waves in the brain
Date:4/26/2009

activity with precise timing via a laser and an optical fiber over the brain," explains co-lead author Marie Carln, a postdoctoral fellow at the Picower Institute.

The trick for inducing gamma waves was the selective activation of the "fast-spiking" interneurons, named for their characteristic pattern of electrical activity. When these cells were driven with high frequency laser pulses, the illuminated region of cortex started to produce gamma oscillations. "We've shown for the first time that it is possible to induce a specific brain state by activating a specific cell type" says co-author Christopher Moore, associate professor of neuroscience and an investigator in the McGovern Institute. In contrast, no gamma oscillations were induced when the fast-spiking interneurons were activated at low frequencies, or when a different class of neurons was activated.

The authors further showed that these brain rhythms regulate the processing of sensory signals. They found that the brain's response to a tactile stimulus was greater or smaller depending on exactly where the stimulus occurred within the oscillation cycle. "It supports the idea that these synchronous oscillations are important for controlling how we perceive stimuli," says Moore. "Gamma rhythms might serve to make a sound louder, or a visual input brighter, all based on how these patterns regulate brain circuits."

Because this new approach required a merger of expertise from neuroscience and molecular genetics, three different laboratories contributed to its completion. In addition to Tsai, Moore and Carln of MIT, co-authors include Jessica Cardin, research affiliate at the McGovern Institute and the University of Pennsylvania, and Karl Deisseroth and Feng Zhang at Stanford University. Other co-authors were Konstantinos Meletis, a postdoctoral fellow at the Picower Institute, and Ulf Knoblich, a graduate student in MIT's Department of Brain and Cognitive Sciences.


'/>"/>

Contact: Elizabeth Thomson
thomson@mit.edu
617-258-5402
Massachusetts Institute of Technology
Source:Eurekalert

Page: 1 2

Related biology news :

1. Making a point: Picoscale stability in a room-temperature AFM
2. It takes a genome: How a clash between our genes and modern life is making us sick
3. MacArthur Foundation awards planning grant to improve decision-making in energy policy
4. U of Minnesota research finds most road salt is making it into the states lakes and rivers
5. Process can cut the cost of making cellulosic biofuels
6. How chromosomes meet in the dark -- Switch that turns on X chromosome matchmaking
7. Tips for making a green holiday from the worlds largest scientific society
8. Making the ultimate family sacrifice
9. Scientists present moving theory behind bacterial decision-making
10. Making flies sick reveals new role for growth factors in immunity
11. Making metabolism more inefficient can reduce obesity
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/23/2015)... June 22, 2015 ... addition of the "Body-Worn Temperature Sensors Market ... and Forecast 2014 - 2020" report to ... analysis of the global body-worn temperature sensors market. ... segmented on the basis of types, care setting, ...
(Date:6/23/2015)... BEACH GARDENS, Fla. , June 23, ... multi-factor identity management and authentication solutions, today announced ... Altus strong, multi-factor authentication solution.  The enhancements ... of use of the DigitalPersona Altus platform ... biometric reader compatibility. In today,s ...
(Date:6/18/2015)... NXT-ID, Inc. (NASDAQ: NXTD ) ("NXT-ID" or ... mobile commerce market announces that its Wocket® smart wallet will ... the Mark", scheduled to air on WABC Radio (am770) in ... . The broadcast air- time for the ... EST. NXT-ID, Inc.,s CEO Gino Pereira will be ...
Breaking Biology News(10 mins):Body-Worn Temperature Sensors Market - Global Industry Analysis 2Crossmatch Releases Enhanced DigitalPersona Altus Advanced Authentication Functionality 2NXT-ID, Inc.'s CEO Gino Pereira Talks About the Wocket Smart Wallet on WABC Radio, New York City, June 20th 2NXT-ID, Inc.'s CEO Gino Pereira Talks About the Wocket Smart Wallet on WABC Radio, New York City, June 20th 3
... have documented an organ-specific innate immune system. In ... journal Immunity, scientists at the University of California, San ... by which the lung shapes its defensive strategies against ... to the lung, and was probably designed to minimize ...
... rare genetic immune system disorder that prevents them from ... lead productive lives, according to results of a study ... report on this study appears in the current online ... 41 adults with X-linked agammaglobulinemia (XLA) showed that they ...
... journal Nature, scientists at the National Institute of Allergy ... Health (NIH) describe a new understanding about how long-term ... thinking about how to enhance certain immune responses and ... Germain, M.D., Ph.D., the scientists took videos through a ...
Cached Biology News:Researchers reveal lung's unique innate immune system 2Patients now surviving once-fatal immune disease 2Patients now surviving once-fatal immune disease 3Chemical guidance of T cells leads to immunologic memory and long-term immunity 2Chemical guidance of T cells leads to immunologic memory and long-term immunity 3
(Date:7/2/2015)... 2, 2015 Amici Procurement Migrates ... company Amici Procurement has chosen Microsoft Cloud Solution Provider ... to Office 365.      (Logo: http://photos.prnewswire.com/prnh/20121126/579634) , ... medium-sized companies in the bio-tech sector with a unique ... purchasing cycle to help them obtain best value. Its ...
(Date:7/1/2015)... ... ... It is now possible to separate two common disorders: post-traumatic stress disorder ... according to researchers from Amen Clinics, UCLA, Thomas Jefferson University, and University of ... to be the largest brain imaging study ever, will be published on July 1, ...
(Date:7/1/2015)... ... July 01, 2015 , ... The next-generation sequencing (NGS) ... market segments, including the molecular diagnostics industry. BCC Research reveals in its new report ... tests, lower test costs, and a growing need for better diagnostics as part of ...
(Date:7/1/2015)... July 1, 2015  Axovant Sciences Ltd. (NYSE: ... the treatment of dementia, today announced that the ... 22 at 5:45 p.m. EDT following its presentation ... International Conference 2015 (AAIC). The ... , Dr. Lawrence Friedhoff , Chief Development ...
Breaking Biology Technology:Biotech Procurement Company Moves to Office 365 with iomart 2Brain Scans Can Tell Post-Traumatic Stress Disorder and Traumatic Brain Injury Apart According to New Research by Amen Clinics 2Brain Scans Can Tell Post-Traumatic Stress Disorder and Traumatic Brain Injury Apart According to New Research by Amen Clinics 3Brain Scans Can Tell Post-Traumatic Stress Disorder and Traumatic Brain Injury Apart According to New Research by Amen Clinics 4NGS-Based Diagnostics, the ‘Must-Have Platform’, Sends Market Segment CAGRs Soaring According to BCC Research 2NGS-Based Diagnostics, the ‘Must-Have Platform’, Sends Market Segment CAGRs Soaring According to BCC Research 3Axovant Sciences To Host Investor Briefing And Live Webcast During AAIC 2015 Meeting 2Axovant Sciences To Host Investor Briefing And Live Webcast During AAIC 2015 Meeting 3
... 13 The Pittsburgh Life Sciences,Greenhouse (PLSG), ... formation and business growth services to the ... has invested $100,000 in,ParentPlus. ParentPlus was formed ... and provide subfertile couples,worldwide better odds of ...
... DIEGO, Dec. 13 Sangart, Inc., a privately ... of oxygen transport agents, today announced that an,independent ... of both Phase III clinical trials of Sangart,s ... This recommendation follows the DSMB,s review of the ...
... DeviceSpace.com, the premier,online community for the ... the inaugural edition of the US Device(TM) ... online,careers, news, event, company and other valuable ... diagnostics industries. The US Device(TM),Hotbed campaign features ...
Cached Biology Technology:The Pittsburgh Life Sciences Greenhouse Invests $100,000 in ParentPlus 2Independent Data Safety Monitoring Board Recommends Continuation of Sangart's Pivotal Phase III Trials of Hemospan(R) 2DeviceSpace.com Launches Marketing Campaign for US Medical Device Industry 2
...
Kit for testing the ability of a compound to simulate lipolysis in cultured human adipocytes. Kit contains controls, buffers and reagents for detecting glycerol and non-esterified free fatty acids. A...
The strip cap tool is a used for properly seating 8- and 12-cap strips in microplates or strip tubes. A grooved channel on one side is designed to seat domed caps, while the flat edge on the opposite...
... Time- and temperature-controlled microwave oven ... and Antigen Retrieval of formalin-fixed, ... ease of use, high throughput ... high performance. When used in ...
Biology Products: