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MIT: Jeremy Nathans to deliver Scolnick Prize lecture
Date:4/23/2009

important because they are prototypes of a large family of proteins known as G-protein-coupled receptors. These proteins are key signaling molecules in all known organisms, and they represent the targets for about 1/3 of all FDA-approved drugs.

In more recent studies, Nathans and his colleagues discovered how genes control the normal development of the retina, and how defects in these genes disrupt the function and survival of retinal cells. These studies have revealed several defects that lead to human retinal diseases including Stargardt disease, the most common type of macular degeneration in children and young adults.

Nathans and colleagues also determined that the vitelliform type of macular dystrophy is caused by abnormalities in a member of a previously unknown family of ion channels proteins that allow ions to enter and exit cells.


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Contact: Julie Pryor
jpryor@mit.edu
617-715-5397
McGovern Institute for Brain Research
Source:Eurekalert  

Page: 1 2

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