Navigation Links
MIT: Bacteria may readily swap beneficial genes
Date:11/1/2011

Much as people can exchange information instantaneously in the digital age, bacteria associated with humans and their livestock appear to freely and rapidly exchange genetic material related to human disease and antibiotic resistance through a mechanism called horizontal gene transfer (HGT).

In a paper appearing in Nature online Oct. 30, researchers led by Eric Alm of MIT's Department of Civil and Environmental Engineering and Department of Biological Engineering say they've found evidence of a massive network of recent gene exchange connecting bacteria from around the world: 10,000 unique genes flowing via HGT among 2,235 bacterial genomes.

HGT is an ancient method for bacteria from different lineages to acquire and share useful genetic information they didn't inherit from their parents. Scientists have long known about HGT and known that when a transferred gene confers a desirable trait, such as antibiotic resistance or pathogenicity, that gene may undergo positive selection and be passed on to a bacterium's own progeny, sometimes to the detriment of humans. (For example, the proliferation of antibiotic-resistant strains of bacteria is a very real threat, as seen in the rise of so-called "superbugs.")

But until now, scientists didn't know just how much of this information was being exchanged, or how rapidly. The MIT team's work illustrates the vast scale and rapid speed with which genes can proliferate across bacterial lineages.

"We are finding [completely] identical genes in bacteria that are as divergent from each other as a human is to a yeast," says Alm, the Karl Van Tassel Associate Professor. "This shows that the transfer is recent; the gene hasn't had time to mutate."

"We were surprised to find that 60 percent of transfers among human-associated bacteria include a gene for antibiotic resistance," adds computational systems biology graduate student Chris Smillie, one of the lead authors of the paper.
'/>"/>

Contact: Kimberly Allen
allenkc@mit.edu
617-253-2702
Massachusetts Institute of Technology
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Hey, bacteria, get off of my boat!
2. VTT identified specific bacteria which precede autoimmune diabetes
3. Do bacteria age? Biologists discover the answer follows simple economics
4. Researchers generate first complete 3-D structures of bacterial chromosome
5. Study proves new technology kills bacteria
6. New bacteria toxins against resistant insect pests
7. Bacteria forge nitrogen from nitric oxide
8. University of California Santa Barbara study reveals how gas, temperature controlled bacterial response to Deepwater Horizon spill
9. Study: Residential washers may not kill hospital-acquired bacteria
10. Bionic bacteria may help fight disease and global warming
11. UTHealth student earns fellowships to research major source of bacterial infections
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/16/2014)... new school year, a new football season and another ... September, SpaceX,s Dragon spacecraft is scheduled to blast off ... part of the company,s fourth contracted mission to the ... third suite of research investigations sponsored by the Center ... the role of managing the U.S. National Laboratory on ...
(Date:9/16/2014)... of the Keystone XL pipeline (KXL) would likely increase ... and researchers surveyed by the non-profit organization Near Zero. ... The Climate Impact," and includes both supporters and opponents ... of oil sands could lead to significantly higher greenhouse ... how markets respond. , "This report examines three ...
(Date:9/16/2014)... this week, its Government could face an uphill challenge ... research has revealed. , The University of Nottingham Shale ... gas extraction in the UK since March 2012 and ... are the least supportive of fracking. , Professor Sarah ... of Geography, said: "The clear move against shale gas ...
Breaking Biology News(10 mins):CASIS research set for launch aboard SpaceX mission to space station 2CASIS research set for launch aboard SpaceX mission to space station 3Keystone XL would likely raise oil sands production and greenhouse gas emissions 2Scottish people most sceptical on fracking, survey shows 2Scottish people most sceptical on fracking, survey shows 3
... is an integral part of modern cancer treatment, but ... ability of anticancer drugs to escape from the bloodstream ... Predicting chemotherapy,s efficacy could save thousands of individuals ... of the treatments. In a study published in ...
... Broad Institute of Harvard and MIT and Beth Israel ... of previously unrecognized mammalian genes that do not encode ... findings, presented in the February 1st advance online issue ... novel class of "large intervening non-coding RNAs" or "lincRNAs" ...
... of Juan de Fuca, which separates Washington state from ... toxic harmful algal blooms affecting the Washington and British ... conditions, toxic algal cells from an offshore "initiation site" ... they may trigger harmful algal blooms that ultimately force ...
Cached Biology News:New technique images tumor vessel leakiness to predict breast cancer chemotherapy outcome 2New technique images tumor vessel leakiness to predict breast cancer chemotherapy outcome 3Scientists uncover new class of non-protein coding genes in mammals with key functions 2Scientists uncover new class of non-protein coding genes in mammals with key functions 3'Hot spot' for toxic harmful algal blooms discovered off Washington coast 2
(Date:9/16/2014)... field of molecular electronics could take our definition ... construction of tiny circuits from molecular components. In ... on the roles currently played by comparatively-bulky wires, ... from five Japanese and Taiwanese universities has identified ... a molecule called picene. In a paper published ...
(Date:9/16/2014)... September 16, 2014 BlueInGreen® ... most efficient method for delivering dissolved gases into ... Inc. as a manufacturer’s representative firm to ... dissolution products for municipal water and wastewater applications ... , H2Flow was founded in 1992 and serves ...
(Date:9/16/2014)... CIRTEC Medical Systems’ Board of Directors has ... CIRTEC. , “I am delighted to be joining ... Brian Highley. “The company has made great strides improving ... over the past two years. The goal now is ... expand the services Cirtec offers its medical device customers.” ...
(Date:9/16/2014)... (PRWEB) September 16, 2014 ... initiatives to position themselves for their 89th ... labeling and encoding, Pharma Packaging Solutions is ... hardware and software and new procedures. Establishing ... Good Manufacturing Practices (cGMP), Pharma Packaging Solutions ...
Breaking Biology Technology:The future face of molecular electronics 2BlueInGreen® Expands into Canada – Signs Representative Agreement with H2Flow Equipment Inc. 2Adding Serialization Capabilities and Expanded Capacity, Pharma Packaging Solutions Is Preparing for 89th Year of Business 2
... (Nasdaq: MNKD ), focused on discovering, developing and,commercializing ... present at the UBS Global Life Sciences Conference on ... Hyatt Hotel in New York, NY. Interested parties ... of the,presentation in the Investor Relations section of the ...
... Sept. 18 InterMune, Inc.,(Nasdaq: ITMN ) today ... other conditions, 3,000,000 shares of its common stock in ... underwriters,a 30-day option to purchase up to an additional ... All of the shares in the offering,will be sold ...
... Sept. 18 /PRNewswire-FirstCall/-- Biodel Inc. (Nasdaq:,BIOD) today ... program,at the 43rd Scientific Sessions of the ... VIAject(TM) Phase II meal study data ... entitled, "Pharmacokinetics and pharmacodynamics of,insulin VIAject(TM), insulin ...
Cached Biology Technology:InterMune Announces Proposed Public Offering of Common Stock 2Biodel Inc. Announces VIAject(TM) Phase II Meal Study Data at the 2007 European Association for the Study of Diabetes Meeting 2Biodel Inc. Announces VIAject(TM) Phase II Meal Study Data at the 2007 European Association for the Study of Diabetes Meeting 3
The S. cerevisiae Hansen strains are the parental yeast strains from which the deletions were derived....
The DNA DipStick Kit is ideal for estimating nucleic acid concentrations and approximate yields. Works with ss- and ds-DNA, RNA, and oligonucleotides at concentrations as low as 0.1 ng/l....
... NEW HandyStep electronic from BRAND adds ... It is the only electronic, motor-driven ... syringe tips, including BRAND PD-Tip syringe ... Fisherbrand Dispenser Tips,and VWRbrand Combi-Syringes. Select ...
The pYES2 vector is designed for native expression of your protein of interest in S. cerevisiae. It contains the URA3 gene for selection in yeast and 2 origin for high-copy maintenance....
Biology Products: