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METACARDIS: a European project that deciphers the genes of the gut microbiota
Date:12/4/2012

ies on an already established patient cohort (MetaHIT and Micro-Obes projects; > 200 subjects). This cohort will provide the teams with immediate access to a wide range of clinical, medical and environmental data as well as biological specimens. The teams will thus be able to conduct initial research on CMD biomarkers by means of a metabolomic approach and metagenomic profiling. A second patient cohort with CMDs at various stages will be set up during the project in three countries (France, Denmark, Germany). Enrolment is scheduled to end in mid-2015. More than 2000 patients, nearly half of the cohort, will come from the Heart and Metabolism Centre of Piti-Salptrire Hospital.

Information on the patients' lifestyle (nutrition, physical activity and psychosocial factors) will be integrated with their clinical and biological data in order to evaluate how they influence the gut microbiota and the progression of associated diseases. This data will be combined with interventional studies that are recognised to reduce the risks of CMDs.


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Contact: Inserm press office
presse@inserm.fr
INSERM (Institut national de la sant et de la recherche mdicale)
Source:Eurekalert

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