Navigation Links
METACARDIS: a European project that deciphers the genes of the gut microbiota
Date:12/4/2012

tients' clinical and biological information.

METACARDIS is the first systemic study designed to correlate the gut microbiota with CMD in people.

It brings together groups of European researchers from various disciplines with biotech and industry experts. The teams will have access to state-of-the-art technologies to accelerate the development of novel preventive and therapeutic strategies for CMDs. Amongst these teams are those directed by Karine Clment and Dominique Gauguier of the Cordeliers Research Centre (Inserm Unit 872) and of the university hospital and research complex ICAN, by Serge Hercberg of the Nutritional Epidemiology unit (Inserm Unit 557) and by Herv Blottire, Joel Dore and Dusko Ehrlich at INRA (France's National Institute of Agricultural Research).

The preliminary studies forming the basis of the METACARDIS project

Work conducted in recent years to characterise the genome of the gut microbiota, i.e. the entire genome of the bacteria in the intestine, has opened up new opportunities in in-depth understanding of the possible channels shared by the various conditions that comprise CMDs.

In oncology, biological signatures that make it possible to predict the characteristics of tumours have been identified. Likewise, research has shown that gene expression models of the gut microbiota vary from one cardiometabolic condition to another. Obese patients presenting insulin resistance, inflammatory syndrome, dyslipidaemia and/or glucose dysregulation are characterised by an alteration in the diversity and composition of their gut microbiota. Some species of gut bacteria have even been found to be associated with coronary vascular diseases. Imbalances in gut intestinal flora therefore may play a role in the development of cardiometabolic conditions.

Patients included in the project in late 2012

Once the METACARDIS project begins in late 2012, its teams will conduct a first series of stud
'/>"/>

Contact: Inserm press office
presse@inserm.fr
INSERM (Institut national de la sant et de la recherche mdicale)
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Toward an European open biodiversity knowledge management system
2. Devotes, a project to investigate marine biodiversity and the environment of European seas
3. Mongolia and the Altai Mountains: Origins of genetic blending between Europeans and Asians
4. European boost for DNA nanotechnology
5. BiOptix to highlight new 404pi instrument at European symposia
6. Ukraine to Introduce European Standard of Biometric ID
7. First Indian-European research networking projects in the social sciences launched
8. PETA files complaint with European ombudsman over animal testing for REACH
9. Citizen science helps unlock European genetic heritage
10. European Society of Human Reproduction and Embryology 28th Annual Meeting -- Istanbul
11. European mountain plant population shows delayed response to climate change
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/19/2014)... this week,s Eos: Long-Term Ecological Research and Network-Level Science, ... how a wide range of ecosystems was responding to ... be particularly powerful if it coupled multiple decades of ... long-term experiments and models from dozens of different ecosystem ... is the Long-Term Ecological Research (LTER) Network, which will ...
(Date:8/19/2014)... fish purchased at retail seafood counters in 10 ... can expose consumers to unexpectedly high levels of ... falsely present a fish of the same species, ... dangerous mislabeling offense, according to new research by ... labeling of seafood is essential to allow consumers ...
(Date:8/19/2014)... Some infants born with neonatal abstinence syndrome (NAS) ... difficult time going through withdrawal than others, but ... genetic and epigenetic (when genes are turned on ... potential factors, researchers at Boston University School of ... a first of its kind study to identify ...
Breaking Biology News(10 mins):This week from AGU: Long-term ecological research, predicting cholera outbreaks 2Seafood substitutions can expose consumers to unexpectedly high mercury 2Seafood substitutions can expose consumers to unexpectedly high mercury 3In-utero methadone, Subutex exposure could alter gene expression, cause severe Neonatal Abstience Syndrome 2
... University of North Carolina at Chapel Hill School of Medicine ... collateral circulation the "back-up" blood vessels that can provide ... attack or stroke. The new knowledge could help inform ... drugs or procedures that can cause new collaterals to form ...
... "The Sign of the Four" Sherlock Holmes tells Watson he ... and pipe-tobacco, "with colored plates illustrating the difference in the ... miscreants who happen to smoke during the commission of a ... pipe dottle don,t have a patch on geologists and the ...
... closer to understanding what triggers muscle damage in one ... facioscapulohumeral muscular dystrophy (FSHD). FSHD affects about 1 ... and wasting of muscles in the face, shoulders and ... disabling. The facial weakness in FSHD, for example, ...
Cached Biology News:Genetics underlie formation of body's back-up bypass vessels 2Geologists revisit the Great Oxygenation Event 2Geologists revisit the Great Oxygenation Event 3Geologists revisit the Great Oxygenation Event 4Geologists revisit the Great Oxygenation Event 5Geologists revisit the Great Oxygenation Event 6Discovery opens door to therapeutic development for FSH muscular dystrophy 2
(Date:8/20/2014)... of patented university inventions licensed to biotechnology firms ... commercialization. To open these roadblocks, the researchers suggest ... the discovery stage could lead to faster commercialization ... derived from discoveries made in university laboratories and ... during clinical trials, which have a high failure ...
(Date:8/20/2014)... For the first time, chemists have succeeded in measuring ... time resolution. The study reveals how vibration of a ... groups. , The study was performed at the ... from the University of Jyvskyl works as a visiting ... in the study. The second team was lead by ...
(Date:8/20/2014)... August 20, 2014 High performance ... apply the most complete climate and Earth system ... climate change issues. , Eight national laboratories, including ... the National Center for Atmospheric Research, four academic ... effort. Other participating national laboratories include Argonne, Brookhaven, ...
(Date:8/20/2014)... Aug. 20, 2014  PAREXEL International Corporation (NASDAQ: ... presenting at the Baird Healthcare Conference in New York.  ... Financial Officer, will be making a presentation on PAREXEL ... Wednesday, Sept. 3, 2014. A live webcast ... section of PAREXEL,s website at www.PAREXEL.com in ...
Breaking Biology Technology:Early bottlenecks in developing biopharmaceutical products delay commercialization 2Early bottlenecks in developing biopharmaceutical products delay commercialization 3Seeing a molecule breathe 2New Project Is the ACME of Addressing Climate Change 2New Project Is the ACME of Addressing Climate Change 3PAREXEL International To Present At Baird Healthcare Conference 2
... Therapy Remains an Important Option for Women Seeking Relief of ... ... data from the Women,s Health Initiative (WHI) study published,today in the ... the appropriate use of hormone therapy when it is,prescribed to symptomatic, ...
... (Nasdaq: DCGN ) today announced that it will report ... issued on Wednesday, March 12,after the close of the market ... its conference call to discuss these results and recent,operating highlights ... noon GMT., The webcast can be accessed through the ...
... and Work/Life Innovations into Next Generation Life/Health Management ... ... Mass., March 4 CaseNET, Inc., a provider of,innovative enterprise care ... (NYSE: CNC ), has selected,the CaseNET platform to support its ...
Cached Biology Technology:WHI Findings Published in JAMA Do Not Affect Clinical Guidance for the Appropriate Use of Hormone Therapy 2WHI Findings Published in JAMA Do Not Affect Clinical Guidance for the Appropriate Use of Hormone Therapy 3WHI Findings Published in JAMA Do Not Affect Clinical Guidance for the Appropriate Use of Hormone Therapy 4deCODE genetics Announces Webcast of Conference Call to Discuss Full-year 2007 Financial Results 2Nurtur(TM) Selects CaseNET to Enable Integrated Health and Life Management Capabilities 2
... At the forefront of Agilent analytical ... Built-in local area networking (LAN) allows you ... sites--for fast and informed decision making. Just ... has all the flexibility and performance needed ...
... Inc.'s CP-4900 is a rugged, ... delivers the information you need ... the composition of gas mixtures ... micro-Gas Chromatograph generates more data ...
... GC system combines world-class performance hardware, Cerity ... Agilents world-renowned support and columns, as well ... combination that lets you reach uncompromising results ... dependable data. The Agilent 6820 GC system ...
... Peroxisome Proliferator-Activated Receptor-gamma (PPARGamma) Competitor ... and efficient method for studying ... using fluorescence polarization (FP). The ... domain (PPARGamma-LBD) with an N-terminal ...
Biology Products: