Navigation Links
MERS coronavirus can be transmitted from camel to man
Date:5/2/2014

The so-called Middle East respiratory syndrome (MERS) coronavirus was first found in June 2012 in a patient from Saudi Arabia, who suffered from severe pneumonia. Since this time more than 300 persons have developed an infection, of whom about a third died. The fact that the Arabian camel is the origin of the infectious disease has been confirmed recently. The transmission pathways of the viruses, however, have not been clear until now.

Viruses in humans and camels from one region are identical

Virologists Norbert Nowotny and Jolanta Kolodziejek from the Institute of Virology are investigating the transmission pathways of the MERS coronavirus. They found that viruses from infected humans and Arabian camels from the same geographical region have nearly identical RNA sequences. "This indicates transmission between animals and man. The process is referred to as zoonosis. With this knowledge we can specifically react to the spread of the virus. Vaccinations of camels are currently being discussed. We will thus be able to halt the spread of the virus," said Nowotny.

Virus RNA differs from region to region

The scientists investigated nasal and conjunctival swabs, taken from 76 camels in Oman. In five camels they found the MERS coronavirus and compared its RNA with those of MERS coronavirus from Qatar and Egypt. The analysis showed that the viruses differ from region to region. "This means that there is no specific 'camel MERS coronavirus strain', but that one virus infects both, camels and humans," says study coordinator Norbert Nowotny.

Transmission pathway through nose and eyes

Virus levels were surprisingly high in the nasal mucosa and conjunctiva of camels. Therefore the scientists presume that the transmission pathway from animals to humans most likely occurs through these contact sites, especially through nasal discharge.

In man the virus causes severe pneumonia and renal failure while camels show no or very little symptoms (in some cases nasal discharge). So far all infections in humans have occurred in the Arabian Peninsula. However, some developed the disease after they returned to their native country, of whom eleven were from Europe. MERS coronavirus is also transmitted from one human to another, for instance in families, in the community, or through contact between patients and medical staff.

MERS and SARS coronaviruses are relatives

MERS coronavirus is closely related to SARS coronavirus. SARS originated in China and claimed 800 lives worldwide in 2002 and 2003. "While the SARS coronavirus probably crossed the species barrier only once by passing from bats to humans, we may presume that the MERS coronavirus is being constantly transmitted from camels to humans," explains Nowotny.

The fact that MERS coronaviruses infect camels was shown by Nowotny and his colleagues in an earlier study, in which the scientists detected antibodies against the virus in the animals. The link to the study: http://www.sciencedirect.com/science/article/pii/S1473309913701646 The current genetic analysis of MERS coronarviruses permits more exact conclusions.


'/>"/>

Contact: Norbert Nowotny
norbert.nowotny@vetmeduni.ac.at
University of Veterinary Medicine -- Vienna
Source:Eurekalert  

Related biology news :

1. New SARS-like coronavirus discovered in Chinese horseshoe bats
2. Curing coronavirus with curiosity
3. Scientists engineer strain of MERS coronavirus for use in a vaccine
4. Researchers describe potential for MERS coronavirus to spread internationally
5. Novel coronavirus well-adapted to humans, susceptible to immunotherapy
6. New coronavirus has many potential hosts, could pass from animals to humans repeatedly
7. New coronavirus related to viruses from bats
8. Study reveals new ways deadly squirrelpox is transmitted to red squirrels
9. Fetal stress disrupts the way genes are transmitted
10. Few pregnant women treated for sexually transmitted infections
11. Study shows disease spread in ladybirds with sexually transmitted disease
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
MERS coronavirus can be transmitted from camel to man
(Date:4/28/2016)... 28, 2016 First quarter 2016:   ... compared with the first quarter of 2015 The gross ... M (loss: 18.8) and the operating margin was 40% (-13) ... Cash flow from operations was SEK 249.9 M (21.2) , ... is unchanged, SEK 7,000-8,500 M. The operating margin for ...
(Date:4/19/2016)... , UAE, April 20, 2016 ... implemented as a compact web-based "all-in-one" system solution for ... biometric fingerprint reader or the door interface with integration ... modern access control systems. The minimal dimensions of the ... readers into the building installations offer considerable freedom of ...
(Date:4/14/2016)... 2016 BioCatch ™, the ... announced the appointment of Eyal Goldwerger as ... Goldwerger,s leadership appointment comes at a time of ... deployment of its platform at several of the world,s ... discerns unique cognitive and physiological factors, is a winner ...
Breaking Biology News(10 mins):
(Date:6/27/2016)... ... , ... Parallel 6 , the leading software as a service (SaaS) ... Virtual Patient Encounter CONSULT module which enables both audio and video telemedicine communication between ... Using the CONSULT module, patients and physicians can schedule a face to face virtual ...
(Date:6/24/2016)... 2016  Regular discussions on a range of subjects including ... two entities said Poloz. Speaking at a lecture ... , he pointed to the country,s inflation target, which is ... "In certain areas there ... common economic goals, why not sit down and address strategy ...
(Date:6/23/2016)... (PRWEB) , ... June 23, 2016 , ... ... is pleased to announce the launch of their brand, UP4™ Probiotics, into Target ... over 35 years, is proud to add Target to its list of well-respected ...
(Date:6/23/2016)... ... 23, 2016 , ... Charm Sciences, Inc. is pleased to ... AOAC Research Institute approval 061601. , “This is another AOAC-RI approval of the ... Vice President of Regulatory and Industrial Affairs. “The Peel Plate methods perform comparably ...
Breaking Biology Technology: