Navigation Links
MERS coronavirus can be transmitted from camel to man
Date:5/2/2014

The so-called Middle East respiratory syndrome (MERS) coronavirus was first found in June 2012 in a patient from Saudi Arabia, who suffered from severe pneumonia. Since this time more than 300 persons have developed an infection, of whom about a third died. The fact that the Arabian camel is the origin of the infectious disease has been confirmed recently. The transmission pathways of the viruses, however, have not been clear until now.

Viruses in humans and camels from one region are identical

Virologists Norbert Nowotny and Jolanta Kolodziejek from the Institute of Virology are investigating the transmission pathways of the MERS coronavirus. They found that viruses from infected humans and Arabian camels from the same geographical region have nearly identical RNA sequences. "This indicates transmission between animals and man. The process is referred to as zoonosis. With this knowledge we can specifically react to the spread of the virus. Vaccinations of camels are currently being discussed. We will thus be able to halt the spread of the virus," said Nowotny.

Virus RNA differs from region to region

The scientists investigated nasal and conjunctival swabs, taken from 76 camels in Oman. In five camels they found the MERS coronavirus and compared its RNA with those of MERS coronavirus from Qatar and Egypt. The analysis showed that the viruses differ from region to region. "This means that there is no specific 'camel MERS coronavirus strain', but that one virus infects both, camels and humans," says study coordinator Norbert Nowotny.

Transmission pathway through nose and eyes

Virus levels were surprisingly high in the nasal mucosa and conjunctiva of camels. Therefore the scientists presume that the transmission pathway from animals to humans most likely occurs through these contact sites, especially through nasal discharge.

In man the virus causes severe pneumonia and renal failure while camels show no or very little symptoms (in some cases nasal discharge). So far all infections in humans have occurred in the Arabian Peninsula. However, some developed the disease after they returned to their native country, of whom eleven were from Europe. MERS coronavirus is also transmitted from one human to another, for instance in families, in the community, or through contact between patients and medical staff.

MERS and SARS coronaviruses are relatives

MERS coronavirus is closely related to SARS coronavirus. SARS originated in China and claimed 800 lives worldwide in 2002 and 2003. "While the SARS coronavirus probably crossed the species barrier only once by passing from bats to humans, we may presume that the MERS coronavirus is being constantly transmitted from camels to humans," explains Nowotny.

The fact that MERS coronaviruses infect camels was shown by Nowotny and his colleagues in an earlier study, in which the scientists detected antibodies against the virus in the animals. The link to the study: http://www.sciencedirect.com/science/article/pii/S1473309913701646 The current genetic analysis of MERS coronarviruses permits more exact conclusions.


'/>"/>

Contact: Norbert Nowotny
norbert.nowotny@vetmeduni.ac.at
University of Veterinary Medicine -- Vienna
Source:Eurekalert  

Related biology news :

1. New SARS-like coronavirus discovered in Chinese horseshoe bats
2. Curing coronavirus with curiosity
3. Scientists engineer strain of MERS coronavirus for use in a vaccine
4. Researchers describe potential for MERS coronavirus to spread internationally
5. Novel coronavirus well-adapted to humans, susceptible to immunotherapy
6. New coronavirus has many potential hosts, could pass from animals to humans repeatedly
7. New coronavirus related to viruses from bats
8. Study reveals new ways deadly squirrelpox is transmitted to red squirrels
9. Fetal stress disrupts the way genes are transmitted
10. Few pregnant women treated for sexually transmitted infections
11. Study shows disease spread in ladybirds with sexually transmitted disease
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
MERS coronavirus can be transmitted from camel to man
(Date:4/4/2017)... 4, 2017   EyeLock LLC , a leader ... United States Patent and Trademark Office (USPTO) has issued ... linking of an iris image with a face image ... the company,s 45 th issued patent. ... timely given the multi-modal biometric capabilities that have recently ...
(Date:3/30/2017)... ANGELES , March 30, 2017  On April ... Hack the Genome hackathon at Microsoft,s ... exciting two-day competition will focus on developing health and ... Hack the Genome is the ... been tremendous. The world,s largest companies in the genomics, ...
(Date:3/30/2017)... Trends, opportunities and forecast in this market ... (fingerprint, AFIS, iris recognition, facial recognition, hand geometry, vein ... use industry (government and law enforcement, commercial and retail, ... others), and by region ( North America ... Pacific , and the Rest of the World) ...
Breaking Biology News(10 mins):
(Date:10/11/2017)... Bay, Florida (PRWEB) , ... October 11, 2017 ... ... and Drug Administration (FDA) has granted orphan drug designation to SBT-100, its novel ... (sdAb) for the treatment of osteosarcoma. SBT-100 is able to cross the cell ...
(Date:10/10/2017)... ... October 10, 2017 , ... ... program has won a US2020 STEM Mentoring Award. Representatives of the FirstHand program ... in Volunteer Experience from US2020. , US2020’s mission is to change the trajectory ...
(Date:10/10/2017)... , Oct. 10, 2017 SomaGenics announced ... the NIH to develop RealSeq®-SC (Single Cell), expected to ... profiling small RNAs (including microRNAs) from single cells using ... highlights the need to accelerate development of approaches to ... "New techniques for measuring levels of ...
(Date:10/9/2017)... Oct. 9, 2017  BioTech Holdings announced today ... which its ProCell stem cell therapy prevents limb ... The Company, demonstrated that treatment with ProCell resulted ... saved as compared to standard bone marrow stem ... resulted in reduction of therapeutic effect.  ...
Breaking Biology Technology: