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MERS coronavirus can be transmitted from camel to man
Date:5/2/2014

The so-called Middle East respiratory syndrome (MERS) coronavirus was first found in June 2012 in a patient from Saudi Arabia, who suffered from severe pneumonia. Since this time more than 300 persons have developed an infection, of whom about a third died. The fact that the Arabian camel is the origin of the infectious disease has been confirmed recently. The transmission pathways of the viruses, however, have not been clear until now.

Viruses in humans and camels from one region are identical

Virologists Norbert Nowotny and Jolanta Kolodziejek from the Institute of Virology are investigating the transmission pathways of the MERS coronavirus. They found that viruses from infected humans and Arabian camels from the same geographical region have nearly identical RNA sequences. "This indicates transmission between animals and man. The process is referred to as zoonosis. With this knowledge we can specifically react to the spread of the virus. Vaccinations of camels are currently being discussed. We will thus be able to halt the spread of the virus," said Nowotny.

Virus RNA differs from region to region

The scientists investigated nasal and conjunctival swabs, taken from 76 camels in Oman. In five camels they found the MERS coronavirus and compared its RNA with those of MERS coronavirus from Qatar and Egypt. The analysis showed that the viruses differ from region to region. "This means that there is no specific 'camel MERS coronavirus strain', but that one virus infects both, camels and humans," says study coordinator Norbert Nowotny.

Transmission pathway through nose and eyes

Virus levels were surprisingly high in the nasal mucosa and conjunctiva of camels. Therefore the scientists presume that the transmission pathway from animals to humans most likely occurs through these contact sites, especially through nasal discharge.

In man the virus causes severe pneumonia and renal failure
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Contact: Norbert Nowotny
norbert.nowotny@vetmeduni.ac.at
University of Veterinary Medicine -- Vienna
Source:Eurekalert  

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