Navigation Links
MERS coronavirus can be transmitted from camel to man
Date:5/2/2014

The so-called Middle East respiratory syndrome (MERS) coronavirus was first found in June 2012 in a patient from Saudi Arabia, who suffered from severe pneumonia. Since this time more than 300 persons have developed an infection, of whom about a third died. The fact that the Arabian camel is the origin of the infectious disease has been confirmed recently. The transmission pathways of the viruses, however, have not been clear until now.

Viruses in humans and camels from one region are identical

Virologists Norbert Nowotny and Jolanta Kolodziejek from the Institute of Virology are investigating the transmission pathways of the MERS coronavirus. They found that viruses from infected humans and Arabian camels from the same geographical region have nearly identical RNA sequences. "This indicates transmission between animals and man. The process is referred to as zoonosis. With this knowledge we can specifically react to the spread of the virus. Vaccinations of camels are currently being discussed. We will thus be able to halt the spread of the virus," said Nowotny.

Virus RNA differs from region to region

The scientists investigated nasal and conjunctival swabs, taken from 76 camels in Oman. In five camels they found the MERS coronavirus and compared its RNA with those of MERS coronavirus from Qatar and Egypt. The analysis showed that the viruses differ from region to region. "This means that there is no specific 'camel MERS coronavirus strain', but that one virus infects both, camels and humans," says study coordinator Norbert Nowotny.

Transmission pathway through nose and eyes

Virus levels were surprisingly high in the nasal mucosa and conjunctiva of camels. Therefore the scientists presume that the transmission pathway from animals to humans most likely occurs through these contact sites, especially through nasal discharge.

In man the virus causes severe pneumonia and renal failure while camels show no or very little symptoms (in some cases nasal discharge). So far all infections in humans have occurred in the Arabian Peninsula. However, some developed the disease after they returned to their native country, of whom eleven were from Europe. MERS coronavirus is also transmitted from one human to another, for instance in families, in the community, or through contact between patients and medical staff.

MERS and SARS coronaviruses are relatives

MERS coronavirus is closely related to SARS coronavirus. SARS originated in China and claimed 800 lives worldwide in 2002 and 2003. "While the SARS coronavirus probably crossed the species barrier only once by passing from bats to humans, we may presume that the MERS coronavirus is being constantly transmitted from camels to humans," explains Nowotny.

The fact that MERS coronaviruses infect camels was shown by Nowotny and his colleagues in an earlier study, in which the scientists detected antibodies against the virus in the animals. The link to the study: http://www.sciencedirect.com/science/article/pii/S1473309913701646 The current genetic analysis of MERS coronarviruses permits more exact conclusions.


'/>"/>

Contact: Norbert Nowotny
norbert.nowotny@vetmeduni.ac.at
University of Veterinary Medicine -- Vienna
Source:Eurekalert  

Related biology news :

1. New SARS-like coronavirus discovered in Chinese horseshoe bats
2. Curing coronavirus with curiosity
3. Scientists engineer strain of MERS coronavirus for use in a vaccine
4. Researchers describe potential for MERS coronavirus to spread internationally
5. Novel coronavirus well-adapted to humans, susceptible to immunotherapy
6. New coronavirus has many potential hosts, could pass from animals to humans repeatedly
7. New coronavirus related to viruses from bats
8. Study reveals new ways deadly squirrelpox is transmitted to red squirrels
9. Fetal stress disrupts the way genes are transmitted
10. Few pregnant women treated for sexually transmitted infections
11. Study shows disease spread in ladybirds with sexually transmitted disease
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
MERS coronavirus can be transmitted from camel to man
(Date:3/31/2016)... 2016   LegacyXChange, ... "Company") LegacyXChange is excited to release its ... to be launched online site for trading 100% guaranteed ... will also provide potential shareholders a sense of the ... an industry that is notorious for fraud. The video ...
(Date:3/29/2016)... RATON, Florida , March 29, 2016 ... or the "Company") LegacyXChange "LEGX" and SelectaDNA/CSI Protect are ... DNA in ink used in a variety of writing ... theft. Buyers of originally created collectibles from athletes on ... through forensic analysis of the DNA. ...
(Date:3/22/2016)... India , March 22, 2016 /PRNewswire/ ... market research report "Electronic Sensors Market for Consumer ... Proximity, & Others), Application (Communication & IT, ... Geography - Global Forecast to 2022", published ... industry is expected to reach USD 26.76 ...
Breaking Biology News(10 mins):
(Date:6/27/2016)... ... 27, 2016 , ... Rolf K. Hoffmann, former senior vice ... University of North Carolina Kenan-Flagler Business School effective June 27. , ... with a focus on the school’s international efforts, leading classes and participating in ...
(Date:6/24/2016)... 2016 Epic Sciences unveiled a liquid ... to PARP inhibitors by targeting homologous recombination deficiency ... new test has already been incorporated into numerous ... types. Over 230 clinical trials are ... including PARP, ATM, ATR, DNA-PK and WEE-1. Drugs ...
(Date:6/23/2016)... ... 2016 , ... UAS LifeSciences, one of the leading manufacturers ... Probiotics, into Target stores nationwide. The company, which has been manufacturing high quality ... list of well-respected retailers. This list includes such fine stores as Whole Foods, ...
(Date:6/23/2016)... June 23, 2016 Houston Methodist Willowbrook ... Cy-Fair Sports Association to serve as their official ... Houston Methodist Willowbrook will provide sponsorship support, athletic ... with association coaches, volunteers, athletes and families. ... Cy-Fair Sports Association and to bring Houston Methodist ...
Breaking Biology Technology: