Navigation Links
MDC researcher Zsuzsanna Izsvák receives advanced European research grant
Date:2/16/2012

Dr. Zsuzsanna Izsvk, research group leader at the Max Delbrck Center for Molecular Medicine (MDC) Berlin-Buch, has been named recipient of a European Research Council (ERC Advanced) grant worth EUR 1.94 million for her research on "jumping genes" (transposons). With the aid of the ERC grant, in the next five years she will focus on investigating how mobile DNA elements (transposons) influence the pathogenesis of cancer and other diseases in the human genome. Altogether, nine MDC researchers, including Dr. Izsvk, have received grants of more than one million euros from the ERC.

About half of the human genome consists of transposon-derived sequences. Active transposons can jump to various sites of the DNA, insert themselves into the genome of the host and continue to spread in this way. Due to this characteristic, transposons are also called "jumping genes".

As a consequence of mutations, in the course of time most of these "jumping genes" in the human genome have lost their mobility; only a few are still active. These remnants of transposons were long considered to be without any function. However, latest studies have shown that transposons are by no means "junk DNA", but rather can influence the regulation of genes.

"The human genome is much more complex than previously assumed. In many processes in the body and also in disease, transposons may be the decisive factor," Dr. Izsvk said. "That is why we need to take a closer look at transposons and their influence."

With the ERC grant, Dr. Izsvk wants to explore the influence of transposons under stress conditions that are triggered by environmental influences, such as toxins or heavy metals, and to understand the association between transposon-derived regulatory sequences and human diseases. Furthermore, together with her team, Dr. Izsvk wants to advance the use of artificially produced transposons for gene therapy.

Dr. Izsvk has worked for over twenty years in transposon research. After several years of research at the University of Minnesota in Minneapolis/USA and at the Netherlands Cancer Institute in Amsterdam, the Hungarian researcher joined the MDC in Berlin-Buch in 1999. She has headed the research group "Mobile DNA" since 2004. At an award ceremony in Stockholm that same year she received the European Young Investigator Award (EURYI), endowed with approximately one million euros, for her research on mobile genetic elements.


'/>"/>
Contact: bachtler@mdc-berlin.de
bachtler@mdc-berlin.de
49-309-406-3896
Helmholtz Association of German Research Centres
Source:Eurekalert

Related biology news :

1. Wistar Institute researcher receives New Innovator award from NIH
2. NC State researchers get to root of parasite genome
3. Researchers find animal with ability to survive climate change
4. Researchers find an essential gene for forming ears of corn
5. Researchers note differences between people and animals on calorie restriction
6. Researcher working on destruction of chemical weapons
7. Researchers study acoustic communication in deep-sea fish
8. Researchers discover that growing up too fast may mean dying young in honey bees
9. Researchers study how pistachios may improve heart health
10. UI researchers find potentially toxic substance present in Chicago air
11. Researchers develop new self-training gene prediction program for fungi
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/9/2017)... , March 9, 2017 4Dx has ... World Lung Imaging Workshop at the University of Pennsylvania. ... invited to deliver the latest data to world leaders ... event brings together leaders at the forefront of the ... lung imaging. "The quality of the ...
(Date:3/6/2017)... Calif. , March 6, 2017 ... and sales technology, today announced Predictive Sales Coach ... for infusing actionable sales intelligence into Salesforce. This ... automatically enable their sales organizations with deep knowledge ... that allow for intelligent engagement. Predictive Sales Coach ...
(Date:3/2/2017)... Australian stem cell and regenerative medicine company, ... an agreement with the Monash Lung Biology Network, a ... and Department of Pharmacology at Monash University, ... to support the use of Cymerus™ mesenchymal stem cells ... Asthma is a chronic, long term lung condition recognised ...
Breaking Biology News(10 mins):
(Date:3/22/2017)... ... March 21, 2017 , ... Functional near-infrared spectroscopy (fNIRS), an optical imaging tool ... way to track the brain’s response to acute pain in adults and infants. , ... ,” published today in the journal Neurophotonics , by SPIE, the international ...
(Date:3/22/2017)... 22, 2017  RXi Pharmaceuticals Corporation (NASDAQ: RXII), ... address significant unmet medical needs, today announced ... will present at the 5th Annual Cancer BioPartnering ... platform to present to and meet with thought ... biotech companies as well as institutional investors. This ...
(Date:3/20/2017)... CA (PRWEB) , ... March 20, 2017 , ... ... therapies for gastrointestinal (GI) disorders, today announced that it has entered into an ... for therapies in inflammatory bowel disease including Necrotizing Enterocolitis (rare orphan disease) as ...
(Date:3/20/2017)... Foreside, Maine (PRWEB) , ... March 20, 2017 ... ... announce its VALIDATE® HEPARIN calibration verification / linearity test kit has received US ... systems. The VALIDATE® HEPARIN kit evaluates Heparin Anti-Xa activity in a human ...
Breaking Biology Technology: