Navigation Links
MCG researcher among first to receive NIH stimulus funding
Date:5/19/2009

AUGUSTA, Ga. A Medical College of Georgia nurse researcher is among the first in the nation to receive National Institutes of Health stimulus funding through the American Recovery and Reinvestment Act of 2009.

The two-year, $147,000 grant will support at least three jobs and the research of African-Americans in the Augusta community who may suffer from cocaine-related renal disease. The recovery act seeks to create or save more than 3.5 million jobs over the next two years.

"It's the realization of a long-time dream to launch my research career and help medically underserved communities," says Dr. Beth NeSmith, assistant professor of physiological and technological nursing in the MCG School of Nursing and the grant's principal investigator.

The National Institute on Drug Abuse funding also will support Stacey Crawford, a research assistant and study coordinator whose previous funding was withdrawn following the relocation of a research faculty member, and Dr. Rosalind Jones, an assistant professor of health environments and systems, who will serve as a grant sub-investigator.

The multidisciplinary research team also includes three MCG School of Medicine faculty members: Dr. Peter Buckley, chair of the Department of Psychiatry and Health Behavior, Dr. Harold Szerlip, professor in the Sections of Nephrology, Hypertension and Transplantation Medicine and Pulmonary Disease, and Dr. John Catravas, director of the MCG Vascular Biology Center and senior associate dean for basic science research.

According to the U.S. Department of Health and Human Services, cocaine is the most frequently reported illicit drug associated with drug-related deaths, and African-Americans are disproportionately affected.

Dr. NeSmith hypothesizes that cocaine use, which can cause increased inflammation and lead to heart and lung disease, might contribute to renal disease in African-Americans, a group that is already at a disproportionately high risk for the disease.

"Studies have shown that cocaine can affect organ function, but the specific effect on renal function has not been well-established," Dr. NeSmith says.

She will compare urine levels of microalbuminuria, a biomarker for early renal disease, in a group of cocaine-dependent African-Americans to a control group who don't use the drug.

"If cocaine-dependent African-Americans have occult renal disease that not been clinically identified yet, that would make a difference when deciding a treatment plan," Dr. NeSmith says.

Some drugs used to treat cocaine addiction have adverse effects on the kidneys, so it's important to know if a patient suffers from asymptomatic renal disease. If that's the case, alternative drug doses or treatments could be used.

The study also will examine the relationship between microalbuminuria levels with blood levels of several inflammation biomarkers. Inflammation is linked to chronic stress, which poses another setback for this patient population by making them increasingly susceptible to organ failure, especially after trauma.

"Many people who are involved in trauma are also substance abusers," Dr. NeSmith says. "If we're able to identify a population with sub-clinical renal problems before potentially life-threatening trauma occurs, treatment can be tailored to the patient's physiology by keeping all existing comorbidities in mind."

The findings of this pilot study will be used to develop further studies focused on early diagnosis and treatment of cocaine-related complications to reduce morbidity, Dr. NeSmith says


'/>"/>

Contact: Paula Hinely
phinely@mcg.edu
706-721-3646
Medical College of Georgia
Source:Eurekalert  

Related biology news :

1. Researchers identify proteins involved in new neurodegenerative syndrome
2. Texas researchers and educators head for Antarctica
3. MGH researchers describe new way to identify, evolve novel enzymes
4. University of Pennsylvania researchers develop formula to gauge risk of disease clusters
5. University of Oregon researcher finds that on waters surface, nitric acid is not so tough
6. U of MN researchers discover noninvasive diagnostic tool for brain diseases
7. U of Minnesota researchers discover noninvasive diagnostic tool for brain diseases
8. Researchers discover new strategies for antibiotic resistance
9. Researchers find new taste in fruit flies: carbonated water
10. Binghamton University researchers investigate evolving malaria resistance
11. Antioxidant to retard wrinkles discovered by Hebrew University researcher
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
MCG researcher among first to receive NIH stimulus funding
(Date:12/15/2016)... Calif. , Dec. 15, 2016   WaferGen ... publicly held genomics technology company, announced today that on ... Listing Qualifications Department of The Nasdaq Stock Market LLC ... closing bid price of WaferGen,s common stock had been ... Accordingly, WaferGen has regained compliance with Listing Rule 5550(a)(2) ...
(Date:12/15/2016)... "Increase in mobile transactions is driving the growth of ... expected to grow from USD 4.03 billion in 2015 ... of 29.3% between 2016 and 2022. The market is ... smart devices, government initiatives, and increasing penetration of e-commerce ... to grow at a high rate during the forecast ...
(Date:12/7/2016)... India , December 7, 2016 According to a ... Machine Learning), Software Tool (Facial Expression, Voice Recognition), Service, Application Area, End User, ... is estimated to grow from USD 6.72 Billion in 2016 to USD 36.07 ... Continue Reading ... ...
Breaking Biology News(10 mins):
(Date:1/18/2017)... HACKENSACK, N.J. , Jan. 18, 2017   ... leading the fight to end Duchenne muscular dystrophy ... awarded to the New Jersey Institute of Technology (NJIT) ... ongoing exploration of robotic technology to assist ... study to incorporate NJIT,s technology – an embedded computer, ...
(Date:1/18/2017)... ... January 18, 2017 , ... Total Orthopedics ... implanted SpineFrontier’s A-CIFT™ Solofuse-P™. The operation took place on Wednesday, January 11, 2017 ... procedure was an anterior cervical discectomy and fusion on a 42 year old ...
(Date:1/18/2017)... ... January 18, 2017 , ... Announced ... Manufacturing Innovation Institutes (MII). U.S. Secretary of Commerce Penny Pritzker has announced the ... the Department of Defense has announced the award of a new Advanced Regenerative ...
(Date:1/18/2017)... , ... January 18, 2017 , ... Researchers from a new study are ... fall low enough after prostate cancer treatment, this indicates there is still remaining prostate cancer ... mortality. , “ The PSA test has always been an indicator of whether a man’s ...
Breaking Biology Technology: