Navigation Links
MCG researcher among first to receive NIH stimulus funding
Date:5/19/2009

AUGUSTA, Ga. A Medical College of Georgia nurse researcher is among the first in the nation to receive National Institutes of Health stimulus funding through the American Recovery and Reinvestment Act of 2009.

The two-year, $147,000 grant will support at least three jobs and the research of African-Americans in the Augusta community who may suffer from cocaine-related renal disease. The recovery act seeks to create or save more than 3.5 million jobs over the next two years.

"It's the realization of a long-time dream to launch my research career and help medically underserved communities," says Dr. Beth NeSmith, assistant professor of physiological and technological nursing in the MCG School of Nursing and the grant's principal investigator.

The National Institute on Drug Abuse funding also will support Stacey Crawford, a research assistant and study coordinator whose previous funding was withdrawn following the relocation of a research faculty member, and Dr. Rosalind Jones, an assistant professor of health environments and systems, who will serve as a grant sub-investigator.

The multidisciplinary research team also includes three MCG School of Medicine faculty members: Dr. Peter Buckley, chair of the Department of Psychiatry and Health Behavior, Dr. Harold Szerlip, professor in the Sections of Nephrology, Hypertension and Transplantation Medicine and Pulmonary Disease, and Dr. John Catravas, director of the MCG Vascular Biology Center and senior associate dean for basic science research.

According to the U.S. Department of Health and Human Services, cocaine is the most frequently reported illicit drug associated with drug-related deaths, and African-Americans are disproportionately affected.

Dr. NeSmith hypothesizes that cocaine use, which can cause increased inflammation and lead to heart and lung disease, might contribute to renal disease in African-Americans, a group that is already at a disproportionately high risk for the disease.

"Studies have shown that cocaine can affect organ function, but the specific effect on renal function has not been well-established," Dr. NeSmith says.

She will compare urine levels of microalbuminuria, a biomarker for early renal disease, in a group of cocaine-dependent African-Americans to a control group who don't use the drug.

"If cocaine-dependent African-Americans have occult renal disease that not been clinically identified yet, that would make a difference when deciding a treatment plan," Dr. NeSmith says.

Some drugs used to treat cocaine addiction have adverse effects on the kidneys, so it's important to know if a patient suffers from asymptomatic renal disease. If that's the case, alternative drug doses or treatments could be used.

The study also will examine the relationship between microalbuminuria levels with blood levels of several inflammation biomarkers. Inflammation is linked to chronic stress, which poses another setback for this patient population by making them increasingly susceptible to organ failure, especially after trauma.

"Many people who are involved in trauma are also substance abusers," Dr. NeSmith says. "If we're able to identify a population with sub-clinical renal problems before potentially life-threatening trauma occurs, treatment can be tailored to the patient's physiology by keeping all existing comorbidities in mind."

The findings of this pilot study will be used to develop further studies focused on early diagnosis and treatment of cocaine-related complications to reduce morbidity, Dr. NeSmith says


'/>"/>

Contact: Paula Hinely
phinely@mcg.edu
706-721-3646
Medical College of Georgia
Source:Eurekalert  

Related biology news :

1. Researchers identify proteins involved in new neurodegenerative syndrome
2. Texas researchers and educators head for Antarctica
3. MGH researchers describe new way to identify, evolve novel enzymes
4. University of Pennsylvania researchers develop formula to gauge risk of disease clusters
5. University of Oregon researcher finds that on waters surface, nitric acid is not so tough
6. U of MN researchers discover noninvasive diagnostic tool for brain diseases
7. U of Minnesota researchers discover noninvasive diagnostic tool for brain diseases
8. Researchers discover new strategies for antibiotic resistance
9. Researchers find new taste in fruit flies: carbonated water
10. Binghamton University researchers investigate evolving malaria resistance
11. Antioxidant to retard wrinkles discovered by Hebrew University researcher
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
MCG researcher among first to receive NIH stimulus funding
(Date:3/29/2017)... the health IT company that operates the largest health ... today announced a Series B investment from BlueCross BlueShield ... investment and acquisition accelerates higi,s strategy to create the ... activities through the collection and workflow integration of ambient ... secures data today on behalf of over 36 million ...
(Date:3/27/2017)... CENTRE, N.Y. , March 27, 2017 /PRNewswire-USNewswire/ ... Healthcare Information and Management Systems Society (HIMSS) Analytics ... Outpatient EMR Adoption Model sm . In addition, ... 12% of U.S. hospitals using an electronic medical ... CHS for its high level of EMR usage ...
(Date:3/24/2017)... Research and Markets has announced the addition of the ... Industry Forecast to 2025" report to their offering. ... The Global Biometric Vehicle Access ... 15.1% over the next decade to reach approximately $1,580 million by ... and forecasts for all the given segments on global as well ...
Breaking Biology News(10 mins):
(Date:10/11/2017)... ... 11, 2017 , ... A new study published in Fertility ... fresh in vitro fertilization (IVF) transfer cycles. The multi-center matched cohort ... After comparing the results from the fresh and frozen transfer cohorts, the authors ...
(Date:10/10/2017)... Poway, California (PRWEB) , ... October 10, 2017 , ... ... afternoon speaking at his local San Diego Rotary Club. The event ... San Diego, CA and had 300+ attendees. Dr. Harman, DVM, MPVM was joined ...
(Date:10/9/2017)... Oct. 9, 2017  BioTech Holdings announced today ... which its ProCell stem cell therapy prevents limb ... The Company, demonstrated that treatment with ProCell resulted ... saved as compared to standard bone marrow stem ... resulted in reduction of therapeutic effect.  ...
(Date:10/7/2017)... ... October 06, 2017 , ... ... applications consulting for microscopy and surface analysis, Nanoscience Instruments is now expanding ... offers a broad range of contract analysis services for advanced applications. Services ...
Breaking Biology Technology: