Navigation Links
M.I.N.D. Institute researchers call for fragile X testing throughout the lifespan
Date:11/25/2008

(SACRAMENTO, Calif.) Writing in this week's Journal of the American Medical Association, UC Davis M.I.N.D. Institute researchers urge physicians to test for mutations of the fragile X gene in patients of all ages. That's because, after decades of research, it is clear that mutations in this gene cause a range of diseases, including neurodevelopmental delays and autism in children, infertility in women and neurodegenerative disease in older adults.

"We want to notify specialists in a variety of areas, as well as allied health professionals, of the potential impact of the fragile X mutation at different times in patients' lives," said Randi Hagerman, director of the Fragile X Research and Treatment Center at the UC Davis M.I.N.D. Institute.

Hagerman, who is also the institute's medical director, co-authored the commentary with fellow M.I.N.D. Institute researcher and husband, Paul Hagerman, who is also director of the UC Davis NeuroTherapeutics Research Institute (NTRI).

Without testing for fragile X mutations, the Hagermans write, patients can be misdiagnosed.

"These patients don't have the advantage of targeted treatments and specific therapies," Randi Hagerman said.

The families of these patients are also at risk because the mutations are passed on from generation to generation.

"The patients don't realize that a genetic mutation is causing all of these seemingly unrelated diseases in their families," she said.

Research by the Hagermans and others has shown that mutations of the fragile X gene can cause, among other disorders, autism and ADHD in children, anxiety disorders at all ages, early menopause in women and dementia in the elderly.

Because the potential impact is so great, M.I.N.D. Institute researchers have created an inexpensive spot blood test for newborn screening that is currently in clinical trials.

Until testing for fragile X is widespread, the Hagermans ur
'/>"/>

Contact: Phyllis Brown
phyllis.brown@ucdmc.ucdavis.edu
916-734-9023
University of California - Davis - Health System
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. EPA teams with National Geographic Society and World Resources Institute to map ecosystem services
2. Salk researcher Terry Sejnowski elected to Institute of Medicine
3. Broad Institute awarded major grant to bolster epigenomics research
4. Swiss Institute of Bioinformatics celebrates 10th birthday by presenting major gifts to human health
5. Wistar Institute researcher receives New Innovator award from NIH
6. Swiss Institute of Bioinformatics 10th Anniversary Conference
7. Syracuse University partners with Serum Institute of India to develop vaccines for children
8. Cornell gets $10 million NSF grant to establish new sustainability institute
9. Eli and Edythe L. Broad make unprecedented gift to endow Broad Institute of Harvard & MIT
10. NYU Cancer Institute researcher among first NIH EUREKA award recipients
11. Broad Institute awarded grant to develop chemical probes for human biology and disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/16/2013)... 16, 2013 Integrated Biometrics patented LES ... custom thin film transistor camera introduces Sherlock, a ... image in the smallest and lightest form factor ... F Mobile ID FAP 45, Certified scanner is ... size and weight when compared to optical scanners. ...
(Date:5/16/2013)... 23 million years old give unprecedented insight into ... of the most species-rich groups among the modern ... Bettina Reichenbacher from the Division of Paleontology and ... Sciences at Ludwig-Maximilians-Universitaet (LMU) in Munich / Germany ... which they assign to the group of bony ...
(Date:5/16/2013)... (GWA), where the entirety of an individual,s DNA is ... which can cause health problems is a massively useful ... pose major ethical problems if used incorrectly, say new ... published on line today (16 May 2013) in the ... based on whole genome and on exome* sequencing and ...
Breaking Biology News(10 mins):Paleontology: The eloquence of the otoliths 2Paleontology: The eloquence of the otoliths 3European Society of Human Genetics urges caution over use of new genetic sequencing techniques 2
... awarded today at the IOF WCO-ECCEO10 Congress in Florence ... award honours an individual researcher who has significantly advanced ... work. It underlines an important aspect of IOF,s mission ... to promote medical innovation, scientific excellence and improved care. ...
... director of the Walter and Eliza Hall Institute from ... in the institute,s Molecular Genetics of Cancer division. ... Professor Doug Hilton, said he was delighted Professor Cory ... institute are immensely proud of this latest of Suzanne,s ...
... -- (May 6, 2010) -- With thousands of scientists across ... to fight disease, there,s a growing emphasis on finding the ... research from Rice University and the University of Cambridge suggests ... role in hematopoietic stem cells (HSCs), the self-renewing cells the ...
Cached Biology News:Suzanne Cory becomes first-elected woman president of AAS 2Stem cells: In search of a master controller 2
(Date:5/17/2013)... May 17, 2013 - Elsevier, a world-leading provider of ... announced the publication of a recent study in ... human blastocysts showing that those with an abnormal chromosomal ... they have developed to blastocysts, thereby classifying the risk ... study the same group has undertaken a retrospective study, ...
(Date:5/17/2013)... 2013  Cellular Biomedicine Group (OTCQB: CBMG) today ... the total projected enrollment required for its Phase ... efficacy of the medical technology haMPC (Human Adipose-derived ... To date the trial has had no Severe ... I open label clinical research trial for KOA, ...
(Date:5/17/2013)... Men’s skin is biologically different than women’s skin,( says skin ... known to react more aggressively when hormones change, and acne ... other acne causing factors like P.acnes bacteria and excess dirt ... unsightly acne scars. Adult acne treatment, Probiotic Action shares new ... to reduce and prevent acne scarring. , In order to ...
(Date:5/17/2013)... (PRWEB) May 17, 2013 IAC Industries wants ... a start up laboratory needing to set up and furnish ... to a larger facility within a year’s time. How does ... that the laboratory is temporary? What is efficient and cost-effective? ... modular workstations from IAC Industries. The planners at DisperSol determined ...
Breaking Biology Technology:Breakthrough for IVF? 2Breakthrough for IVF? 3Cellular Biomedicine Group Achieves 50% Enrollment Milestone in Phase I Clinical Trial for Knee Osteoarthritis 2Adult Acne Treatment, Probiotic Action Shares New Insight on Why Men’s Skin Scars from Acne and How to Prevent It 2New Downloadable Success Story: “How To Outfit a Dynamic Lab in Flux” 2
... /PRNewswire-FirstCall/ - Angiotech Pharmaceuticals, Inc. (NASDAQ: ... of a series of new, proprietary Quill(TM) SRS ... invasive, gynecology procedures, including hysterectomies and myomectomies. In ... the United States of which approximately 130,000 were ...
... , , SAN DIEGO, Aug. ... scheduled to present at the Canaccord Adams 29th Annual Global Growth ... 2:00 p.m. Eastern Time. , , (Logo: ... these presentations will be accessible on the Company,s website at ...
... N.J., Aug. 4 DOR BioPharma, Inc., (OTC Bulletin ... company, announced today that the Office of Orphan Products ... (FDA) has granted Orphan Drug Designation to Oral BDP ... symptoms associated with chronic Graft-versus-Host disease (cGVHD) in patients ...
Cached Biology Technology:Angiotech Pharmaceuticals announces launch of Quill SRS product codes for laparoscopic gynecology procedures 2Angiotech Pharmaceuticals announces launch of Quill SRS product codes for laparoscopic gynecology procedures 3Angiotech Pharmaceuticals announces launch of Quill SRS product codes for laparoscopic gynecology procedures 4Angiotech Pharmaceuticals announces launch of Quill SRS product codes for laparoscopic gynecology procedures 5Angiotech Pharmaceuticals announces launch of Quill SRS product codes for laparoscopic gynecology procedures 6Optimer Pharmaceuticals to Present at the Canaccord Adams 29th Annual Global Growth Conference 2DOR BioPharma Receives FDA Orphan Drug Designation for orBec(R) for the Treatment of Chronic Gastrointestinal GVHD 2DOR BioPharma Receives FDA Orphan Drug Designation for orBec(R) for the Treatment of Chronic Gastrointestinal GVHD 3DOR BioPharma Receives FDA Orphan Drug Designation for orBec(R) for the Treatment of Chronic Gastrointestinal GVHD 4DOR BioPharma Receives FDA Orphan Drug Designation for orBec(R) for the Treatment of Chronic Gastrointestinal GVHD 5DOR BioPharma Receives FDA Orphan Drug Designation for orBec(R) for the Treatment of Chronic Gastrointestinal GVHD 6
... This DuoSet ELISA Development kit contains ... of sandwich ELISAs to measure natural and ... supernates and serum. Each kit contains sufficient ... 96-well plates, provided that the following conditions ...
Conjugation services for Antibodies, Proteins, Oligos, Peptides, Beads, bioconjugation, antibody-oligonucleotide, LNA peptide, LNA protein, LNA antibody, HRP, Alkaline phosphatase, phycoerythrin, FIT...
Blimp-1 (H-150)...
SCP-1 (P-17)...
Biology Products: