Navigation Links
Lyme disease bacteria take cover in lymph nodes
Date:6/16/2011

The bacteria that cause Lyme disease, one of the most important emerging diseases in the United States, appear to hide out in the lymph nodes, triggering a significant immune response, but one that is not strong enough to rout the infection, report researchers at the University of California, Davis.

Results from this groundbreaking study involving mice may explain why some people experience repeated infections of Lyme disease. The study appears online in the journal Public Library of Science Biology at: http://tinyurl.com/3vs8pm9.

"Our findings suggest for the first time that Borrelia burgdorferi, the bacteria that cause Lyme disease in people, dogs and wildlife, have developed a novel strategy for subverting the immune response of the animals they infect," said Professor Nicole Baumgarth, an authority on immune responses at the UC Davis Center for Comparative Medicine.

"At first it seems counter intuitive that an infectious organism would choose to migrate to the lymph nodes where it would automatically trigger an immune response in the host animal," Baumgarth said. "But B. burgdorferi have apparently struck an intricate balance that allows the bacteria to both provoke and elude the animal's immune response."

About Lyme disease

Lyme disease, the most important tick-borne disease in the United States is caused by Borrelia burgdorferi, corkscrew-shaped bacteria also known as spirochetes. The disease is transmitted to humans and animals through bites from infected deer ticks.

The disease occurs mainly in the Northeastern and Great Lakes states, and is present to a lesser extent in Northern California. However, the western black-legged tick, the main carrier of Lyme disease in the western United States, has been found in 56 of California's 58 counties, according to the California Department of Public Health.

Symptoms of Lyme disease are quite variable and may
'/>"/>

Contact: Patricia Bailey
pjbailey@ucdavis.edu
530-752-9843
University of California - Davis
Source:Eurekalert

Page: 1 2

Related biology news :

1. GW researchers receive award from NCI to study cancer from a neglected tropical disease
2. First diagnostic test for hereditary childrens disease
3. Scientists find deadly amphibian disease in the last disease-free region of central America
4. Genome sequence could reveal Achilles heels of important wheat disease
5. Potential treatment for deadly E. coli disease
6. Developmental disease is recreated in an adult model
7. A promising new approach to autoimmune diseases
8. Patients with bowel disease eager to test fecal therapy
9. Harvard scientists see the early cellular cause of dry eye disease for the first time
10. Origins of XMRV deciphered, undermining claims for a role in human disease
11. Good guy or bad guy? Diagnosing stomach disease in pet reptiles
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/25/2014)... the first broad-scale estimate of air pollution removal by ... that trees are saving more than 850 human lives ... symptoms. , While trees, pollution removal equated to an ... the impacts of that improvement are substantial. Researchers valued ... at nearly $7 billion every year in a study ...
(Date:7/25/2014)... on the land now called California, and many of ... plants they used for food, fuel, tools, and ritual. ... habitat and natural resources. , Frank Lake, an ecologist ... lead a field trip to the Stone ... America,s 99th Annual Meeting, in Sacramento, Cal. this August. ...
(Date:7/25/2014)... false-color image from the Terra satellite show the different areas ... in Eastern Russia. The burn scars show up as ... wildfires have broken across the remote parts of Eastern Russia ... from the MODIS instrument, it is still possible to ... recent image features noted below show the devastating number of ...
Breaking Biology News(10 mins):First national study finds trees saving lives, reducing respiratory problems 2Fire ecology manipulation by California native cultures 2Fire ecology manipulation by California native cultures 3
... on the tap to get a glass of water, we just ... really safe? And, what exactly is "safe"? The public ... Marylynn Yates , a professor of environmental microbiology at the University ... will help the audience become familiar with the most common causes ...
... and clean people,s water supplies while serving as important ... cranes and alligators. Conventional ecosystem health assessments have focused ... unseen creatures in the wetlands provided crucial indicators of ... Missouri Associate Professor of Engineering Zhiqiang Hu and his ...
... GSA Bulletin articles posted online ahead of ... in central Asia; (2) crystal xenoliths in the Bolivian Altiplano; ... Group contact, Barberton greenstone belt, South Africa; (5) iron oxide ... Alaska syntaxis; (7) paleotopography of the South Norwegian margin; and ...
Cached Biology News:How safe is our drinking water? 2Measuring microbes makes wetland health monitoring more affordable, says MU researcher 2Contacts, collisions, sutures, belts, and margins -- new GSA Bulletin content 2Contacts, collisions, sutures, belts, and margins -- new GSA Bulletin content 3Contacts, collisions, sutures, belts, and margins -- new GSA Bulletin content 4Contacts, collisions, sutures, belts, and margins -- new GSA Bulletin content 5Contacts, collisions, sutures, belts, and margins -- new GSA Bulletin content 6Contacts, collisions, sutures, belts, and margins -- new GSA Bulletin content 7Contacts, collisions, sutures, belts, and margins -- new GSA Bulletin content 8Contacts, collisions, sutures, belts, and margins -- new GSA Bulletin content 9
(Date:7/24/2014)... PARK, Calif. , July 24, 2014 /PRNewswire/ ... company in the emerging field of regenerative medicine, ... webcast of a presentation to investors on Tuesday, ... p.m. PDT.  The presentation will include an overview ... To access the webcast, visit http://www.ustream.tv/channel/asterias-biotherapeutics ...
(Date:7/24/2014)... Distinguished Professor of Engineering at the University of ... solve problems in energy engineering, environmental sustainability and ... zeolites, porous rock with a well-defined, crystalline structure. ... so precisely decided that zeolites can separate molecules ... an angstrom (one-tenth of a nanometer), making them ...
(Date:7/24/2014)... July 24, 2014 SRI International has been ... National Institute of Allergy and Infectious Diseases (NIAID), part ... development of potential therapies for HIV infection and AIDS. ... HIV and AIDS and the complications and opportunistic infections ... preventing sexual transmission of HIV. According ...
(Date:7/24/2014)... 2014 WIRB-Copernicus Group ® ("WCG")™, ... review services for clinical research, announced today that ... of Richmond, VA -based Alliance ... biosecurity consulting firm in the United ... division – WCG Biosafety™ – will be able ...
Breaking Biology Technology:Asterias Biotherapeutics Announces Live Investor Webcast 2Asterias Biotherapeutics Announces Live Investor Webcast 3Asterias Biotherapeutics Announces Live Investor Webcast 4University of Delaware researcher describes new approach for creating organic zeolites 2National Institute of Allergy and Infectious Diseases Awards SRI International Contract to Study New Therapies for HIV and AIDS 2National Institute of Allergy and Infectious Diseases Awards SRI International Contract to Study New Therapies for HIV and AIDS 3WIRB-Copernicus Group Announces Acquisition of Alliance Biosciences; Executives Join WCG Biosafety Division 2WIRB-Copernicus Group Announces Acquisition of Alliance Biosciences; Executives Join WCG Biosafety Division 3
... , SAN MATEO, Calif., Nov. 6 , ... of Qutenza(TM) E.U. Marketing Authorization to Astellas Pharma Europe Ltd. ... Expanded management team to include VP Sales; Senior Director, Marketing; ... board as director and Audit Committee chairman , ...
... Therapeutics, Inc. delivered two presentations today on its ITCA ... treatment of type 2 diabetes at the Ninth Annual ... http://www.newscom.com/cgi-bin/prnh/20050301/SFTU126LOGO ) , Continuous Subcutaneous Delivery ... and Reduces Weight in a 28-day Phase 1b Study ...
... Md., Nov. 5 GenVec, Inc. (Nasdaq: GNVC ) today ... 2009. GenVec reported a net loss of $3.6 million ($0.04 per ... a net loss of $6.8 million ($0.08 per share) in the ... 2009, GenVec,s net loss was $14.1 million ($0.15 per share), compared ...
Cached Biology Technology:NeurogesX Reports Third Quarter 2009 Results 2NeurogesX Reports Third Quarter 2009 Results 3NeurogesX Reports Third Quarter 2009 Results 4NeurogesX Reports Third Quarter 2009 Results 5NeurogesX Reports Third Quarter 2009 Results 6NeurogesX Reports Third Quarter 2009 Results 7NeurogesX Reports Third Quarter 2009 Results 8NeurogesX Reports Third Quarter 2009 Results 9NeurogesX Reports Third Quarter 2009 Results 10Intarcia Therapeutics, Inc. Presents Positive Results from Two Studies of ITCA 650 for the Treatment of Type 2 Diabetes at the Ninth Annual Diabetes Technology Meeting 2Intarcia Therapeutics, Inc. Presents Positive Results from Two Studies of ITCA 650 for the Treatment of Type 2 Diabetes at the Ninth Annual Diabetes Technology Meeting 3Intarcia Therapeutics, Inc. Presents Positive Results from Two Studies of ITCA 650 for the Treatment of Type 2 Diabetes at the Ninth Annual Diabetes Technology Meeting 4Intarcia Therapeutics, Inc. Presents Positive Results from Two Studies of ITCA 650 for the Treatment of Type 2 Diabetes at the Ninth Annual Diabetes Technology Meeting 5GenVec Reports Third Quarter 2009 Financial Results 2GenVec Reports Third Quarter 2009 Financial Results 3GenVec Reports Third Quarter 2009 Financial Results 4GenVec Reports Third Quarter 2009 Financial Results 5GenVec Reports Third Quarter 2009 Financial Results 6
...
... Vacuum pumps deliver critical performance for all ... control optimizes pump performance to suit all ... for convenient checking of proper oil levels ... pumps is designed to work with all ...
... The IITC Life Science Rotarods are used ... motor coordination or fatigue resistance on mice and ... humane way. Extremely user friendly; the animals are ... an animal drops onto the individual sensing platforms ...
... Prostaglandin F2α (8-iso-13,14-dihydro-15-keto PGF2α) is a ... PGF2α), in rabbits, monkeys and humans. ... of non-specific lipid peroxidation. In both ... is converted primarily to metabolites having ...
Biology Products: