Navigation Links
Lush or lightweight?
Date:10/31/2007

ed, they fell from platform to platform until they became so intoxicated that they fell to the bottom of the tube, where they were collected.

"When you expose flies to alcohol, they go through the tube at a rate more or less determined by their genetic background," Mackay said.

By mating the most extreme lightweights with other extreme lightweights for 25 generations and mating extreme lushes with other extreme lushes for 25 generations, the researchers created both "lightweight" flies that needed just a minute or two of exposure to fall to the bottom of the inebriometer and fly "lushes" that finally reached the tube's bottom after a "bender" of about 18 minutes.

More than 1,500 genes changed in testing, the study showed. Tests of 35 especially promising candidate genes showed 32 genes affecting alcohol sensitivity. Seventy-two percent of these 32 genes have human counterparts, the researchers said.

Some of these changed genes are involved in one of the metabolic pathways that converts alcohol into fat, and have not been previously studied for a correlation to alcohol sensitivity, the researchers added.

Finding relevant genes, Mackay says, could some day lead to devising a drug for people with higher genetic risk factors for alcoholism.


'/>"/>

Contact: Trudy Mackay
trudy_mackay@ncsu.edu
919-515-5810
North Carolina State University
Source:Eurekalert

Page: 1 2

Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/17/2014)... Research and Markets ( http://www.researchandmarkets.com/research/9zq33j/global_chemical ) has ... Market 2015-2019" report to their offering. ... trend upcoming in this market is the increasing demand ... in recording of patient data for quick and correct ...
(Date:12/11/2014)... DUBLIN , Dec. 09, 2014 Research and Markets ... ( http://www.researchandmarkets.com/research/twhjll/biometrics_market ) has announced the addition ... 2015-2019"  report to their offering. One ... technology. With continuous advances in technology, it is important ...
(Date:12/11/2014)... ST. PAUL, Minn. , Dec. 10, 2014 ... wireless physiologic monitoring, has released a new series ... needs of preclinical toxicology researchers. M series, part ... help toxicologists collect the best possible physiologic data ...
Breaking Biology News(10 mins):Global Chemical Sensor Market 2015-2019: Key Vendors are Abbott Laboratories, Bayer, Hoffmann La-Roche, Johnson & Johnson, NGK Spark Plugs and Robert Bosch 2Biometrics Market in the APAC Region 2015-2019: Key Vendors are 3M Cogent, NEC, Safran and Suprema 2New telemetry implants expected to change how large animal toxicology studies are conducted 2
... Take advantage of lower early bird registration rates and ... 2010 at http://www.iofwco-ecceo10.org/ WHAT: IOF ... Foundation (IOF) and the European Society for Clinical and ... 5,000 participants from around the world are expected to ...
... report published in the December 2009 print issue of The ... type of control over their fertility that women have had ... where androgenic hormones work in the testis to control normal ... for the development of "the pill" for men. The discovery ...
... sharks are some of the Ocean,s most distinctive residents. ... head shape, says Michelle McComb from Florida Atlantic University. ... visual field has been enhanced by their weird head ... depth perception. However, according to McComb, there were two ...
Cached Biology News:Wide heads give hammerheads exceptional stereo view 2
(Date:1/22/2015)... (PRWEB) January 22, 2015 Protocol Networks ... The growing team of brand-neutral, independent consultants, Protocol Networks ... Rogers explained that over the years, his company has ... Moroso, Town of Plainfield, as well as others. With ...
(Date:1/22/2015)... 22, 2015 Dr. Greg Leyer of UAS ... Scripps Natural Supplements Pre-Conference seminar on probiotics in San Diego, ... annual continuing education conference for health care professionals. This year’s ... topic of probiotics in health. Dr. Leyer spoke about the ...
(Date:1/22/2015)... BRUNSWICK , Nueva Jersey , 22 de ... Award for Biomedical Research abre hoy su llamada a ... personas cuya investigación científica ha hecho, o tiene el ... la salud humana. Las nominaciones se aceptarán hasta el ...
(Date:1/22/2015)... , Jan. 22, 2015  Derma Sciences, Inc. (Nasdaq: ... focused on advanced wound care, announces that AMNIOEXCEL® ... have been added to the Premier, Inc. Regenerative ... opportunity for the AMNIOEXCEL® and AMNIOMATRIX® product lines, ...
Breaking Biology Technology:Protocol Networks Brings Independent Technology Consulting to the Constitution State 2El Dr. Paul Janssen Award for Biomedical Research emite su llamada a los nominados para 2015 2El Dr. Paul Janssen Award for Biomedical Research emite su llamada a los nominados para 2015 3El Dr. Paul Janssen Award for Biomedical Research emite su llamada a los nominados para 2015 4Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 2Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 3Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 4Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 5
... release is available in Spanish and French . ... eons. From this fibrous diet consisting mainly of the tough ... no nutritional value to most animals, ruminants manage to extract all ... And now, the cow, or rather the network of organisms ...
... Media LLC (AHM), announced the appointment of Renee DeFranco as ... the human resources function for the company and play an ... Brady, Chief Executive Officer and President of AHM and is ... "Renee,s extensive human resources and business experience will strengthen AHM,s ...
... research, medical challenges and harsh economics are thwarting efforts ... the United States, according to a trio of nationally ... 27) issue of the journal Neuron . ... strategies are being tested in patients firmly in the ...
Cached Biology Technology:How now, inside the cow: Nearly 30,000 novel enzymes for biofuel production improvements 2How now, inside the cow: Nearly 30,000 novel enzymes for biofuel production improvements 3How now, inside the cow: Nearly 30,000 novel enzymes for biofuel production improvements 4How now, inside the cow: Nearly 30,000 novel enzymes for biofuel production improvements 5Advanced Health Media Company Announces Renee DeFranco as Senior Vice President - Human Resources 2Course correction needed for Alzheimer's therapies, experts warn 2Course correction needed for Alzheimer's therapies, experts warn 3
POU domain, class 2, transcription factor 2,...
... cell line contains the b-lactamase reporter gene ... (CRE). To obtain the cell line the ... cells by lentivirus. Subsequent flow cytometry was ... stimulation (Figure 1). The CellSensor CRE-bla HEK ...
activating transcription factor 4 (tax-responsive enhancer element B67),...
Reactivity: Human...
Biology Products: