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Lupus Research Institute-funded study points to increased risk for lupus in men
Date:9/2/2010

ao's findings demonstrate the power of genetic studies in mouse lupus models to guide the hunt for susceptibility genes in the more complex human disease," said Michel Nussenzweig, MD, PhD, the Sherman Fairchild Professor and a senior physician at Rockefeller University.

Validation of TLR7 in Human Lupus Increases Potential for New Therapies

The search for new therapeutics acting on TLR7 is already underway with candidate drugs in development at several companies.

"This finding strongly confirms the selection of TLR7 as a target for drug therapy, and bolsters the ongoing efforts to develop TLR7 antagonists as future therapeutics for lupus, and further lends credence to the LRI's support of novel research to help find therapies and cures for lupus," said Benjamin Schwartz, MD, PhD, a professor of clinical medicine at the Washington University School of Medicine in St. Louis.


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Contact: Liz Bryan
lbryan@spectrumscience.com
202-955-6222 x2526
Lupus Research Institute
Source:Eurekalert

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