Navigation Links
Lupus Research Institute announces 2009 novel research grants

The Lupus Research Institute (LRI) today named 12 new grant recipients for 2009. The awards, totaling $3.6 million, recognize innovative work across a broad spectrum of lupus research. All were selected for their creativity, novelty, and potential to drive scientific discovery to ultimately prevent, treat, and cure the complex disease of systemic lupus.

The 2009 grants go to both new and established lupus researchers across the nation and include interdisciplinary and highly promising investigations such as:

  • Testing a new way to monitor lupus nephritis (kidney inflammation) without intrusive and sometimes damaging biopsies via noninvasive MRI scans.

  • Pinpointing novel genes specifically associated with lupus in people of African-American ancestrya population more commonly affected by lupus, and also far more likely to experience severe disease.

  • Taking the unconventional approach that nervous system networks modulate inflammation and can be targeted to limit damage to organs in lupus.

"For a decade, the LRI has dedicated itself to innovation and scientific risk-taking in search of new answers and treatments for lupus," said LRI President Margaret G. Dowd. "Recent advances in the corporate sector certainly have demonstrated the value and importance of bold innovation as the pathway to discovery in lupus."

Many of the 2009 grants are innovative studies in human lupus biology that work directly with human tissue in order to hasten the translation of the science into solid human outcomes, advancing the development of new therapies and filling a notable gap in the scientific field.

The $3.6 million in awards to 12 investigators nationwide brings the LRI's total investment for Novel Research Grants to $30 million to 102 investigators at 55 academic medical centers across 22 states.

"A grant from the LRI is known in immunology as very prestigious," said LRI researcher Christopher A.J. Roman, PhD, at the State University of New York Downstate Medical Center (Brooklyn). "Many are very risky grants. They may be built solely upon an idea, as opposed to considerable experimental evidencewhich is normally needed for an NIH proposal. The scientists on the LRI Board have the vision, the foresight and experience to pick those research projects that will hopefully lead to a better understanding of the disease. And then from that, better treatments."

The 2009 LRI grant recipients are:

  • Steven Bensinger, VMD, PhD
    University of California, Los Angeles
    Linking lupus, cardiovascular disease and lipid metabolism

  • Hongbo Chi, PhD
    St. Jude Children's Research Hospital Memphis, TN
    S1P1 receptor in regulatory T cells and lupus pathogenesis and therapy

  • Anne Davidson, MD
    Feinstein Institute for Medical Research Manhasset, NY
    TNF antagonism in SLE

  • Hui-Chen Hsu, PhD
    University of Alabama at Birmingham
    Deletion of lupus autoreactive cells using an anti-hDR5 antibody

  • Timothy Niewold, MD
    University of Chicago Chicago, IL
    Novel Genes Associated with African-American Lupus

  • Marko Radic, PhD
    University of Tennessee Health Science Center Memphis, TN
    Stimulation of Autoreactive B Cells by Apoptotic Bodies

  • Jeffrey Rathmell, PhD
    Duke University Medical Center Durham, NC
    Estrogen Related Receptor-Alpha and B cell Metabolism in SLE

  • Boris Reizis, PhD
    Columbia University Medical Center New York, NY
    Molecular control of self-DNA recognition in lupus

  • Jane Salmon, MD
    Hospital for Special Surgery New York, NY
    Cholinergic modulation of immune complex-mediated inflammatory responses

  • Daniel Stetson, PhD
    University of Washington Seattle, WA
    Cell-Intrinsic Initiation of Autoimmunity in Lupus and Related Diseases

  • Joshua Thurman, MD
    University of Colorado Denver, CO
    Non-Invasive Assessment of Lupus Nephritis

  • Changchun Xiao, PhD
    Scripps Research Institute La Jolla, CA
    Functional Analysis of MicroRNAs in Systemic Immune Tolerance


Contact: Liane Stegmaier
Lupus Research Institute

Related biology news :

1. Study identifies genetic risk factor for rheumatoid arthritis, lupus
2. Lupus Research Institute strategy delivers $30 million in national funding
3. Lupus gene finding prompts call for more DNA samples
4. Profound immune system discovery opens door to halting destruction of lupus
5. New approach for attacking lupus identified
6. UT Southwestern secures $5 million NIH grant for lupus research
7. DNA variations signal lupus risk
8. Genes linked with lupus are revealed, giving hope for new treatments
9. The Alliance for Lupus Research announces 2008 grantees
10. Gene linked to lupus might explain gender difference in disease risk
11. UT Southwestern researchers probe kidney damage, protection in lupus
Post Your Comments:
(Date:11/10/2015)... About signature verification Signature ... identify and verify the identity of an individual ... secure and accurate method of authentication and is ... because each individual,s signature is highly unique. Signature ... signature of an individual is compared and matched ...
(Date:11/9/2015)... 2015  Synaptics Inc. (NASDAQ: SYNA ), the ... entry into the automotive market with a comprehensive and ... of consumer electronics human interface innovation. Synaptics, industry-leading touch ... the automotive industry and will be implemented in numerous ... , Japan , and ...
(Date:11/2/2015)... MENLO PARK, Calif. , Nov. 2, 2015 /PRNewswire/ ... to $9 million to provide preclinical development services to ... Under the contract, SRI will provide scientific expertise, modern ... a wide variety of preclinical pharmacology and toxicology studies ... --> --> The PREVENT Cancer Drug ...
Breaking Biology News(10 mins):
(Date:11/25/2015)... Md. , Nov. 25, 2015  PharmAthene, Inc. ... Directors has adopted a stockholder rights plan (Rights Plan) ... net operating loss carryforwards (NOLs) under Section 382 of ... --> PharmAthene,s use of its NOLs ... "ownership change" as defined in Section 382 of the ...
(Date:11/25/2015)... ANGELES and HOLLISTON, Mass. ... Technology, Inc. (Nasdaq: HART ), a biotechnology company ... that CEO Jim McGorry will present at ... December 1, 2015 at 2:30 p.m. PT. The presentation ... below) for 30 days. Management will also be available ...
(Date:11/25/2015)... ... November 25, 2015 , ... ... Organization of Black Aerospace Professionals (OPBAP) has been formalized with the signing of ... team leaders met with OPBAP leaders Capt. Karl Minter and Capt. Albert Glenn ...
(Date:11/25/2015)... ... November 25, 2015 , ... Jessica Richman ... AngelList early in their initial angel funding process. Now, they are paying it ... to make early stage investments in the microbiome space. In this, they ...
Breaking Biology Technology: