Navigation Links
Lung function declines as chest deformity deepens
Date:8/18/2011

A common deformity that cases a depression in the chest wall inhibits lung function as the cavity grows deeper, a national study of 327 patients published in the Journal of Pediatrics found.

"These results confirm what we have observed anecdotally, that children with more severe pectus excavatum report more incidents of shortness of breath and a higher degree of exercise intolerance," said one of the study's lead authors, Dr. Robert Kelly, a pediatric surgeon at Children's Hospital of The King's Daughters in Norfolk, Virginia.

Pectus excavatum, a condition sometimes known as sunken chest, occurs when the chest cartilage grows abnormally and the chest wall progressively collapses. A CHKD surgeon, Dr. Donald Nuss, developed a minimally invasive surgery to correct the condition 25 years ago, and the hospital has remained at the forefront of treatment and research on chest wall deformities ever since.

The study on lung function included 327 pre-correction pectus excavatum patients ages 6 to 21 from hospitals around the nation, including CHKD. The study used standardized medical measurements to determine the severity of the pectus excavatum and a spirometer, a device that measures the volume of air expelled from the lungs, to assess lung function.

"The results suggest a correlation between the severity of pectus excavatum and lung function," said Dr. Kelly. "The more severe the deformity, the more lung function was compromised." He noted that the effect was primarily from lung restriction, not airway obstruction.

While the decline is relatively modest, Dr. Kelly believes researchers next need to study lung function in pectus excavatum patients at the larger tidal volumes required during exercise.


'/>"/>

Contact: Greg Raver-Lampman
Greg.Lampman@chkd.org
757-668-7554
Children's Hospital of The King's Daughters
Source:Eurekalert

Page: 1

Related biology news :

1. Researchers use human cells to engineer functional anal sphincters in lab
2. Researchers engineer functioning small intestine in laboratory experiments
3. Beyond Darwin: Evolving new functions
4. Unexpected function of dyslexia gene
5. Genome offers clue to functions of destructive wheat fungus
6. Deciding to stay or go is a deep-seated brain function
7. Therapies to improve biochemical functions hold promise as treatments for autism
8. Noninvasive wireless near-infrared device provides reliable diagnosis of bladder dysfunction
9. The aging brain and Alzheimers disease: New ideas for targeting synaptic dysfunction
10. For hearing parts of brain, deafness reorganizes sensory inputs, not behavioral function
11. Researchers show heparan sulfate adjusts functions of growth factor proteins
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/22/2016)... 20, 2016  As part of its longstanding mission to ... genetics company, recently released its latest children,s book, titled ... focuses on the topics of inheritance and variation of traits ... taught in elementary school classrooms in the US. ... illustrator Ariana Killoran , whose previous book with 23andMe, ...
(Date:12/16/2016)... --  IdentyTechSolutions America LLC , a leading provider ... a cutting-edge manufacturer of software and hardware security ... integrated solutions that comprise IDT biometric readers and ... IdentyTech,s customers with combined physical identification and anti-tailgating ... theft. "We are proud to use ...
(Date:12/15/2016)... 2016 ... Research and Markets has announced the addition of the ... The report forecasts the global military biometrics market to grow at ... report has been prepared based on an in-depth market analysis with inputs ... prospects over the coming years. The report also includes a discussion of ...
Breaking Biology News(10 mins):
(Date:1/18/2017)... ... 18, 2017 , ... uBiome, the leading microbial genomics company, ... Editor, Dr. Elisabeth Bik, in the December 2016 issue of the Dutch Journal ... October 2016 from her previous position at Stanford University School of Medicine and ...
(Date:1/18/2017)...  HUYA Bioscience International, (HUYA), the leader in accelerating ... pharmaceutical innovations, announced today a strategic collaboration agreement with ... (referred to as CAS Innovation). The collaboration will focus ... scientists at CAS to meet the medical needs of ... first company to have recognized China,s ...
(Date:1/18/2017)... 18, 2017  Market Research Future published a half-cooked research report ... to grow at a CAGR of 12% during the period 2016 ... ... the abnormal cell division without any control. These abnormal cells have ... These cancer cells can spread to other parts of the body ...
(Date:1/17/2017)... Jan. 17, 2017 The Global Implantable ... CAGR of around 7.5% over the next decade ... of the prominent trends that the market is ... diseases & graft transplant surgeries and medical implants ... market is categorized into immunomodulatory biomaterials, natural, polymers, ...
Breaking Biology Technology: