Navigation Links
Loyola study debunks common myth that urine is sterile
Date:4/9/2012

MAYWOOD, Ill. -- Researchers have determined that bacteria are present in the bladders of some healthy women, which discredits the common belief that normal urine is sterile. These findings were published in the April issue of the Journal of Clinical Microbiology by researchers at Loyola University Chicago Stritch School of Medicine (SSOM).

"Doctors have been trained to believe that urine is germ-free," said Linda Brubaker, MD, MS, dean, SSOM. "However, these findings challenge this notion, so this research may have positive implications for how we treat patients with urinary tract conditions in the future."

This study evaluated urine specimens of women who had symptoms consistent with a urinary tract infection (UTI), but were free of known UTIs. Urine samples were collected from standard urination, through a catheter, or from a thin needle inserted into the abdomen while the women were under anesthesia for gynecologic surgery. The urine was analyzed using advanced DNA-based detection methods. These tests determined that the adult female bladder can contain certain forms of bacteria that are not identified by urine culture techniques that are typically used to diagnose UTIs.

"While urine cultures have been the gold standard to identify UTIs in the past, they have limited utility," said Alan Wolfe, PhD, co-author and professor of Microbiology and Immunology, SSOM. "They are not as effective as the DNA-based detection measures used in this study."

This study also looked at collection methods to test urine for bacteria. The results revealed that the standard method to catch urine in a cup poses problems, because bacteria from the vagina often contaminate these specimens. In contrast, urine collection using a catheter or a needle was effective and comparable between tests.

Loyola researchers now plan to determine which bacteria in the bladder are helpful and which are harmful. They also will look at how these bacteria interact with each other and with their host, and how we can use this information to help patients. This research is in line with a larger international effort that is underway to identify the core bacterial composition of a healthy human body. Researchers strive to correlate changes in the composition of bacterial communities in and on the body with certain diseases.

"Further studies are needed to determine if the bacteria found in the bladders of women in this study are relevant to urinary tract conditions," Dr. Brubaker said. "If that is the case, these studies could make it possible to identify women who are at-risk for these conditions, which may change how we manage patients."


'/>"/>

Contact: Nora Dudley
nodudley@lumc.edu
708-216-6268
Loyola University Health System
Source:Eurekalert

Related biology news :

1. Loyola receives NIH grant to study vitamin D deficiency in African populations
2. Long-term study shows effect of climate change on animal diversity
3. £2 million study to reveal workings of dementia genes
4. New study looks to define evangelicals and how they affect polling
5. CU-Boulder study suggests air quality regulations miss key pollutants
6. Researchers study acoustic communication in deep-sea fish
7. Study reveals homeowner perceptions in fire-prone areas
8. Researchers study how pistachios may improve heart health
9. Study: urban black bears live fast, die young
10. New study indicates link between weight gains during pregnancy and dieting history
11. Study reveals specific gene in adolescent men with delinquent peers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/22/2017)... -- With the biometrics market to exceed $10 ... that innovative and agile startups must incorporate into ... changing competitive landscape: multifactor authentication (MFA), point-of-sale (PoS), ... "Companies can no longer afford to cut corners ... Pavlakis , Industry Analyst at ABI Research. "Pairing ...
(Date:2/14/2017)... , Feb. 14, 2017  Wake Forest Baptist ... as its new chief executive officer (CEO). Freischlag joins ... John D. McConnell , M.D., who last year ... at the Medical Center, after leading it since 2008. ... full scope of Wake Forest Baptist,s academic health system, ...
(Date:2/9/2017)... LONDON , Feb. 9, 2017 The ... in-depth analysis of the biomass boiler market globally in ... sales of biomass boilers. The market for biomass boilers ... product type, end-user, application, and country/region. The market based ... agriculture & forest residues, biogas & energy crops, urban ...
Breaking Biology News(10 mins):
(Date:3/27/2017)... Russian portfolio company of Maxwell Biotech Venture Fund (MBVF), today announced positive results of ... in patients with multidrug-resistant pulmonary tuberculosis (MDR-TB). SQ109 is a new small molecule drug ... National Institutes of Health. Continue Reading ... ... ...
(Date:3/27/2017)... -- The new research portal will give visitors ... on Valero Energy , offering extensive market research on ... ... http://photos.prnewswire.com/prnh/20160330/349511LOGO) The latest trend gaining momentum ... today, even though touted as a green alternative to fossil ...
(Date:3/27/2017)... 27, 2017  Trovagene, Inc. (NASDAQ: TROV), a precision ... Officer, Bill Welch , will be presenting at ... 9:00 AM EDT at the Essex House in ... Chief Scientific Officer, Mark Erlander , Ph.D., will ... conference.   The presentation will be webcast live ...
(Date:3/24/2017)... -- MiMedx Group, Inc. (NASDAQ: MDXG), the leading regenerative ... and patent-protected processes to develop and market advanced products ...  that it will present at the Needham Healthcare Conference ... H. "Pete" Petit, Chairman and CEO, Michael J. ... , EVP and Chief Commercialization Officer, and Mark ...
Breaking Biology Technology: