Navigation Links
Low levels of vitamin B12 may increase risk for neural tube defects
Date:3/1/2009

Children born to women who have low blood levels of vitamin B12 shortly before and after conception may have an increased risk of a neural tube defect, according to an analysis by researchers at the National Institutes of Health, Trinity College Dublin, and the Health Research Board of Ireland.

Women with the lowest B12 levels had 5 times the risk of having a child with a neural tube defect compared to women with the highest B12 levels.

Women who consume little or no meat or animal based foods are the most likely group of women to have low B12 levels, along with women who have intestinal disorders that prevent them from absorbing sufficient amounts of B12.

Neural tube defects are a class of birth defects affecting the brain and spinal cord. One type, spina bifida, can cause partial paralysis. Another type, anencephaly, is a fatal defect in which the brain and skull are severely underdeveloped.

Researchers have known that taking another nutrient, folic acid, during the weeks before and after conception can greatly reduce a woman's chances of having a child with a neural tube defect. Folic acid is the synthetic form of the vitamin folate. In the United States, cereal grains are fortified with folic acid to reduce the occurrence of neural tube defects in the U.S. population.

The study appears in the March Pediatrics. The study's first author was Anne M. Molloy, Ph.D., Trinity College Dublin. Scientists from the Health Research Board of Ireland and two NIH institutes, the Eunice Kennedy Shriver National Institute of Child Health and Human Development and the National Human Genome Research Institute, also took part in the study.

"Vitamin B12 is essential for the functioning of the nervous system and for the production of red blood cells," said Duane Alexander, M.D., director of the NICHD. "The results of this study suggest that women with low levels of B12 not only may risk health problems of their
'/>"/>

Contact: Robert Bock or Marianne Glass Miller
bockr@mail.nih.gov
301-496-5133
NIH/National Institute of Child Health and Human Development
Source:Eurekalert

Page: 1 2 3 4

Related biology news :

1. New genes present drug targets for managing cholesterol and glucose levels
2. Master gene plays key role in blood sugar levels
3. Drops in blood oxygen levels may be key to sudden death in some epilepsy patients
4. In child care, relationships with caregivers key to childrens stress levels
5. Vitamin C lowers levels of inflammation biomarker considered predictor of heart disease
6. Revised theory suggests carbon dioxide levels already in danger zone
7. Global methane levels on the rise again
8. Methane gas levels begin to increase again
9. Milk may help bacteria survive against low levels of antibiotics
10. Drinking water in Gaza Strip contaminated with high levels of nitrate
11. People with heart disease still have trouble controlling blood lipid levels
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/11/2014)... When researchers at the National Institute of Standards ... do their work more effectively, they often prove ... Such was the case recently for M. Lorna ... in the growing specialization of glycomics. Glycomics is ... called glycans that are attached to proteins and ...
(Date:7/11/2014)... Ume University, Sweden, have explored two different ways ... sequence leading to the formation of oxygen molecules ... in the scientific journal Nature Communications . ... day synthetic catalysts for water oxidation, which are ... the direct storage of solar energy in fuels ...
(Date:7/11/2014)... that under the normal circumstances, astrocytes participate ... neuronal environment, and exhibit therapeutic and repairing ... Previous studies have found that nerve cells ... induction have reduced viability, which produces influences ... Yuan, Kailuan General Hospital, Hebei United University, ...
Breaking Biology News(10 mins):Molecular snapshots of oxygen formation in photosynthesis 2
... WI, MARCH 29, 2011 The environmental concern is ... the plant-soil relationship. Understanding plant,s absorption and accumulation of ... One highly carcinogenic contaminant commonly found in soil ... of the incomplete combustion of coal, oil, gas, and ...
... tell a story, these bleached bones that gleam in ... landscapes like Yellowstone may provide detailed accounts of how ... or even century, scientists have found. "The skeletons ... into our understanding of ecosystem history, especially how populations ...
... Researchers at the University of Michigan Comprehensive Cancer Center ... treat multiple types of cancer. A study, published this ... that AT-406 effectively targets proteins that block normal cell death ... while not harming normal cells. The researchers believe the drug ...
Cached Biology News:Bones of long-dead animals conjure ghosts at Yellowstone 2Bones of long-dead animals conjure ghosts at Yellowstone 3New cancer drug discovered at U-M heads to clinical trials 2
(Date:7/10/2014)... 2014 Product and process impurities ... abundance and are often “lost in the noise,” ... Join presenters Dr. Rowel Tobias, Senior Scientist, Protein ... Head of Quality at Nanotherapeutics, Inc., to lear ... speed detection and quantitation while achieving the required ...
(Date:7/10/2014)... (PRWEB) July 10, 2014 Terascala, the ... announced that Alan Swahn, a former vice president of ... team as vice president of marketing. Terascala’s software when ... and NetApp create the highest performance and most reliable ... appointed to guide Terascala’s channel expansion and broaden its ...
(Date:7/10/2014)... OMICS Group’s 5th International conference and exhibition ... at Double Tree by Hilton Beijing, China is all ... & Bioanalytical research methods only to facilitate improved living ... Dr. Srinubabu Gedela, MD of OMICS Group Inc has ... one in bringing a unique and international mix of ...
(Date:7/10/2014)... , July 10, 2014  Franciscan ... use of capnography for respiratory monitoring outside ... of healthcare leaders in embracing state-of-the-art patient ... effectively patients are breathing and can alert ... By measuring the amount of carbon dioxide ...
Breaking Biology Technology:Novel Ms Techniques Speed Detection of Biopharmaceutical Product and Process Impurities, New Webinar Hosted by Xtalks 2Terascala Expands Executive Team 2Terascala Expands Executive Team 3A Critical Review of Analytical Techniques for Improved Living Standards 2A Critical Review of Analytical Techniques for Improved Living Standards 3A Critical Review of Analytical Techniques for Improved Living Standards 4Franciscan St. Anthony Health-Crown Point Underscores Patient Safety Commitment Through Expanded Use of Capnography 2
... hours a day now that a new company has created ... site MusicMadeInMadison.com plays more than 450 songs written ... Burn, Infinite Helix and They Drive By Night. Founded in ... to help both the circulation of the artists and awareness ...
... a lot of Web developers realized some time ago: Flash ... be supported as one. , , In announcements made today ... current and future components of the Flash development platform like ... of course, is the Flash player itself, which is now ...
... and the Wisconsin Technology Council have released a report ... and the difficulties that still need to be addressed ... , ,Wisconsin Technology Council President Tom Still pointed ... Massachusetts have lost 10 to 15 percent of their ...
Cached Biology Technology:Flashing into the future 2Flashing into the future 3Report: Wisconsin still lags in college degrees held by workforce, leads elsewhere 2Report: Wisconsin still lags in college degrees held by workforce, leads elsewhere 3
... has over 23 years of experience in ... have made antibodies to large and small ... antigens, and plasmid DNA-encoded antigens. We understand ... so our hybridoma development programs are never ...
... Rapid-Screen cDNA Library Panels were designed for ... sets of PCRs to identify the desired ... performed in a 96-well "Master Plate," where ... clones. Having identified the positive well(s) by ...
... The Rapid-Screen cDNA Library Panels were ... just three sets of PCRs to identify ... analysis is performed in a 96-well "Master ... from 5,000 clones. Having identified the positive ...
... CBED Maxi Kit provides a fast and ... protein solutions for buffer exchange, and for removing ... kit is based on spin-column chromatography using Norgens ... such as MgCl 2 , NaCl, KCl, CaCl ...
Biology Products: