Navigation Links
Low bone mineral density common in children and teenagers with inflammatory bowel disease
Date:8/23/2010

A thesis from the University of Gothenburg (Sweden) is the first in Scandinavia to study the occurrence of low bone mineral density in children and teenagers with inflammatory bowel disease. Half of the patients in the study showed signs of low bone mineral density. The results emphasise the importance of treating the underlying inflammatory bowel disease more effectively, and of measuring bone mineral density in this group of patients.

Low bone mineral density, or BMD, was evident in around half of the 144 participants with inflammatory bowel disease aged between six and 19 in a major study in western Sweden. Disturbed development of BMD during childhood and adolescence may increase the risk of osteoporosis later in life and thus the likelihood of fractures.

"Possible risk factors for low BMD were more severe disease with increased inflammatory activity in the gut, male gender and low body mass index," says Susanne Schmidt, researcher at the Institute of Clinical Sciences.

Genetic factors also had a major role to play in the children's BMD, aside from their chronic gastrointestinal inflammation which itself can affect BMD.

"We investigated the children's biological parents and measured their BMD," says Schmidt. "We found a clear correlation between the parents' and the children's BMD. Where both parents had a low BMD, a child was six times more likely to have a low BMD too. A similar correlation has previously been described in healthy children and their parents."

However, the researchers saw that after two years the BMD of the oldest patients was showing signs of recovery, which will be investigated more closely in a follow-up study.

According to Schmidt there have, to date, been neither international nor national guidelines for monitoring BMD in children and teenagers with inflammatory bowel disease. She therefore sees a need to introduce checks on BMD, particularly in those patients with risk factors, such as more active disease, low body mass index or parents with a known low BMD.

"The results of the study also underline the importance of optimising the treatment of these patients to minimise the inflammation which is partly behind the low BMD."


'/>"/>

Contact: Susanne Schmidt
schm-sus@online.no
479-416-1405
University of Gothenburg
Source:Eurekalert

Related biology news :

1. Mineral studies advance antibacterial alternatives
2. Dental delight: Tooth of sea urchin shows formation of biominerals
3. Common soil mineral degrades the nearly indestructible prion
4. Adiponectin is a metabolic link between obesity and bone mineral density
5. Mineral oil contamination in humans: A health problem?
6. First nearshore survey of Antarctic krill reveals high density, stable population in shallow waters
7. New process yields high-energy-density, plant-based transportation fuel
8. A matter of density, not quantity
9. Study finds link between hot flashes and lower bone density in women
10. Researchers push nature beyond its limits to create higher-density biofuels
11. Scientists find new twist on drug screening to treat common childhood cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/2/2017)... -- Summary This report provides all the ... its partnering interests and activities since 2010. Download ... Partnering Deals and Alliance since 2010 report provides an ... the world,s leading life sciences companies. On ... inclusion of the most up to date deal and ...
(Date:2/28/2017)... ANGELES , Feb. 28, 2017   Acuant ... verification software globally, announces significant enhancements to new and ... May 2016. New products include mobile and desktop Acuant ... DocX TM - a real time manual review ... core idScanĀ® technology provides the fastest and most accurate ...
(Date:2/26/2017)... Feb. 25, 2017  Securus Technologies, a leading ... for public safety, investigation, corrections and monitoring, announces ... Reentry. "Too often, too many offenders ... county jails are trying to tackle this ongoing ... friends and family members. While significant steps are underway, ...
Breaking Biology News(10 mins):
(Date:3/22/2017)... Regeneron Pharmaceuticals, Inc. (NASDAQ: REGN), today announced a major research ... GSK to generate genetic sequence data from the 500,000 volunteer ... researchers to gain valuable insights to support advances in the ... and life threatening diseases. ... Genetic evidence has revolutionized scientific discovery ...
(Date:3/22/2017)... 2017 Oramed Pharmaceuticals Inc. (NASDAQ: ... ), a clinical-stage pharmaceutical company focused ... announced today that Dr. Miriam Kidron , ... titled, "Oral Insulin for Diabetes Treatment: Bypassing the ... and Peptide Therapeutics (OPT) Boston Conference in ...
(Date:3/22/2017)... , March 22, 2017   Boston Biomedical , ... therapeutics designed to target cancer stemness pathways, today announced ... Andrews as Chief Executive Officer, effective April 24, ... Chiang J. Li , M.D., FACP, who has led ... ago. Under his leadership, Boston Biomedical has grown from ...
(Date:3/22/2017)... ... ... Benchworks CEO Thad L. Bench Sr. will participate in the ... San Diego. The event is a gathering of executive leadership from companies in the ... Meyer will also participate in the forum. Participants will discuss the future of the ...
Breaking Biology Technology: