Navigation Links
Low bone mineral density common in children and teenagers with inflammatory bowel disease
Date:8/23/2010

A thesis from the University of Gothenburg (Sweden) is the first in Scandinavia to study the occurrence of low bone mineral density in children and teenagers with inflammatory bowel disease. Half of the patients in the study showed signs of low bone mineral density. The results emphasise the importance of treating the underlying inflammatory bowel disease more effectively, and of measuring bone mineral density in this group of patients.

Low bone mineral density, or BMD, was evident in around half of the 144 participants with inflammatory bowel disease aged between six and 19 in a major study in western Sweden. Disturbed development of BMD during childhood and adolescence may increase the risk of osteoporosis later in life and thus the likelihood of fractures.

"Possible risk factors for low BMD were more severe disease with increased inflammatory activity in the gut, male gender and low body mass index," says Susanne Schmidt, researcher at the Institute of Clinical Sciences.

Genetic factors also had a major role to play in the children's BMD, aside from their chronic gastrointestinal inflammation which itself can affect BMD.

"We investigated the children's biological parents and measured their BMD," says Schmidt. "We found a clear correlation between the parents' and the children's BMD. Where both parents had a low BMD, a child was six times more likely to have a low BMD too. A similar correlation has previously been described in healthy children and their parents."

However, the researchers saw that after two years the BMD of the oldest patients was showing signs of recovery, which will be investigated more closely in a follow-up study.

According to Schmidt there have, to date, been neither international nor national guidelines for monitoring BMD in children and teenagers with inflammatory bowel disease. She therefore sees a need to introduce checks on BMD, particularly in those patients with risk factors, such as more active disease, low body mass index or parents with a known low BMD.

"The results of the study also underline the importance of optimising the treatment of these patients to minimise the inflammation which is partly behind the low BMD."


'/>"/>

Contact: Susanne Schmidt
schm-sus@online.no
479-416-1405
University of Gothenburg
Source:Eurekalert

Related biology news :

1. Mineral studies advance antibacterial alternatives
2. Dental delight: Tooth of sea urchin shows formation of biominerals
3. Common soil mineral degrades the nearly indestructible prion
4. Adiponectin is a metabolic link between obesity and bone mineral density
5. Mineral oil contamination in humans: A health problem?
6. First nearshore survey of Antarctic krill reveals high density, stable population in shallow waters
7. New process yields high-energy-density, plant-based transportation fuel
8. A matter of density, not quantity
9. Study finds link between hot flashes and lower bone density in women
10. Researchers push nature beyond its limits to create higher-density biofuels
11. Scientists find new twist on drug screening to treat common childhood cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/2/2016)... June 2, 2016 The Department of ... awarded the 44 million US Dollar project, for the ... Plates including Personalization, Enrolment, and IT Infrastructure , ... the production and implementation of Identity Management Solutions. Numerous renowned ... Decatur was selected for the most ...
(Date:5/20/2016)... May 20, 2016  VoiceIt is excited to ... VoicePass. By working together, VoiceIt and ... VoiceIt and VoicePass take slightly different approaches to ... both security and usability. ... this new partnership. "This marketing and ...
(Date:4/28/2016)... and BANGALORE, India , April ... EdgeVerve Systems, a product subsidiary of Infosys (NYSE: ... today announced a global partnership that will provide ... to use mobile banking and payment services.      ... a key innovation area for financial services, but it also ...
Breaking Biology News(10 mins):
(Date:6/27/2016)... 27, 2016  Liquid Biotech USA ... of a Sponsored Research Agreement with The University ... (CTCs) from cancer patients.  The funding will be ... correlate with clinical outcomes in cancer patients undergoing ... then be employed to support the design of ...
(Date:6/24/2016)... ... , ... While the majority of commercial spectrophotometers and fluorometers use the z-dimension ... are higher end machines that use the more unconventional z-dimension of 20mm. Z-dimension ... bottom of the cuvette holder. , FireflySci has developed several Agilent flow cell ...
(Date:6/23/2016)... Mass. , June 23, 2016   ... development of novel compounds designed to target cancer ... napabucasin, has been granted Orphan Drug Designation from ... the treatment of gastric cancer, including gastroesophageal junction ... stemness inhibitor designed to inhibit cancer stemness pathways ...
(Date:6/23/2016)... ... June 23, 2016 , ... Charm Sciences, Inc. is ... has received AOAC Research Institute approval 061601. , “This is another AOAC-RI approval ... Bob Salter, Vice President of Regulatory and Industrial Affairs. “The Peel Plate methods ...
Breaking Biology Technology: