Navigation Links
Low adherence to biopsy guidelines affects celiac disease diagnosis in the United States
Date:7/7/2011

NEW YORK, NY (July 6, 2011) - A new study has found that most patients undergoing biopsy of the small intestine do not have the recommended number of samples to diagnose celiac disease. The study, published in the July 2011 issue of Gastrointestinal Endoscopy, analyzed a national database of biopsy specimens maintained by Caris Life Sciences (Irving, TX). More than 100,000 patients had a biopsy of the small intestine, but only 35 percent of them had at least four samples taken, the number recommended by professional guidelines.

Celiac disease is common, affecting approximately 1 percent of the population in the United States. However, the vast majority of patients with celiac disease in the United States have not been diagnosed. Many of these patients seek health care for symptoms including diarrhea, weight loss, or fatigue due to anemia. The diagnosis of celiac disease is made by biopsy of the small intestine, but factors related to the performance of biopsy may contribute to the under-diagnosis of celiac disease in the United States.

"Celiac disease can affect the small intestine in a patchy distribution, and so just one or two biopsy samples could potentially miss the evidence of the disease," said lead author Benjamin Lebwohl, MD, MS, a gastroenterologist at the Celiac Disease Center at Columbia University Medical Center, in New York. Dr. Lebwohl and co-authors aimed to measure the practice of small intestinal biopsy in the United States. The Caris pathology database consists of specimens submitted by gastroenterologists from 43 states as well as Puerto Rico and the District of Columbia. The team also compared the diagnosis rate among patients who had at least four specimens submitted, in accordance with guidelines.

The investigators identified 132,352 individuals who underwent biopsy between 2006 and 2009, for a variety of medical indications, including diarrhea, abdominal pain, esophageal reflux, and anemia. Only
'/>"/>

Contact: Cynthai Beckman
cb2280@columbia.edu
646-812-1212
Columbia University Medical Center
Source:Eurekalert

Page: 1 2

Related biology news :

1. Link between fracture prevention and treatment adherence not fully understood by patients
2. Novel technique changes lymph node biopsy, reduces radiaiton exposure
3. Novel technique changes lymph node biopsy, reduces radiation exposure
4. Montana State grads work helps diagnose skin cancer without a biopsy
5. Multicolor quantum dots aid in cancer biopsy diagnosis
6. Microfluidics-imaging platform detects cancer growth signaling in minute biopsy samples
7. Guidelines urge physical activity during pregnancy
8. The International Society for Stem Cell Research releases new guidelines
9. Publication sets guidelines across cancer therapies: Ensuring the best in patient management
10. Coral Disease Handbook: Guidelines for Assessment, Monitoring and Management
11. First comprehensive guidelines for managing medullary thyroid carcinoma published in Thyroid journal
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/10/2014)... 27, 2014  The American Academy of Forensic ... Standards and Technology (NIST) and the Department of ... and forensic science expert members to the Forensic ... element of the NIST,s Organization of Scientific Area ... first appointments made to the new FSSB that ...
(Date:7/10/2014)... 1, 2014 Smart technology emphasis grows ... and improved security: NXT-ID, Inc. (OTCBB: NXTD), eBay Inc. (NASDAQ: ... ), Apple Inc. (NASDAQ: AAPL ), Visa Inc. ... NXT-ID, Inc., (OTCQB: NXTD) a biometric authentication company focused ... the second series of 30 second spots on CNBC for ...
(Date:7/10/2014)... July 2, 2014 NXT-ID, Inc., (OTCQB: NXTD) a biometric authentication ... Mr. Gino Pereira was interviewed on July 1 ... Tampa Florida . Mr. Pereira discusses the company,s ... Harris and how the Wocket™ aims to replace a ... Cedric Harris tells Gino he has never ...
Breaking Biology News(10 mins):Ten Members of the American Academy of Forensic Sciences Appointed to Forensic Science Standards Board (FSSB) 2Ten Members of the American Academy of Forensic Sciences Appointed to Forensic Science Standards Board (FSSB) 3Advantages for Digital Wallets Eliminate Need to Carry Credit Cards - Large Scale CNBC Ad Campaign for Latest Smart Wallet to Commence July 7th 2Advantages for Digital Wallets Eliminate Need to Carry Credit Cards - Large Scale CNBC Ad Campaign for Latest Smart Wallet to Commence July 7th 3Advantages for Digital Wallets Eliminate Need to Carry Credit Cards - Large Scale CNBC Ad Campaign for Latest Smart Wallet to Commence July 7th 4Advantages for Digital Wallets Eliminate Need to Carry Credit Cards - Large Scale CNBC Ad Campaign for Latest Smart Wallet to Commence July 7th 5Security and Your Money: Tampa Bay Radio Host Cedric Harris Talks to NXT-ID CEO Mr. Gino Pereira about the Wocket Smart Wallet 2Security and Your Money: Tampa Bay Radio Host Cedric Harris Talks to NXT-ID CEO Mr. Gino Pereira about the Wocket Smart Wallet 3Security and Your Money: Tampa Bay Radio Host Cedric Harris Talks to NXT-ID CEO Mr. Gino Pereira about the Wocket Smart Wallet 4
... years for marine invertebrates living on the Port Valdez ... according to a scientist at the University of Alaska ... Richter scale, and the tsunami waves that followed, impacted ... Blanchard, a research assistant professor at the UAF School ...
... pig population continues to expand, increasing the potential for interaction ... Researchers at North Carolina State University examined feral pigs from ... can be transmitted from animals to people Toxoplasma ... study found that wild pigs host a significant number of ...
... their collaborators have detected the antimatter partner of the ... heaviest antimatter particle ever detected. Scientists at ... detector that identified antihelium-4. The $7.5 million detector was ... Chinese scientists contributing $2.5 million to the project. The ...
Cached Biology News:Port Valdez invertebrates stabilized 26 years after quake 2Wild hogs: Researchers examine impact of feral pigs in eastern N.C. 2Rice-born detector finds heaviest antimatter 2Rice-born detector finds heaviest antimatter 3
(Date:7/11/2014)...  Researchers have pioneered a revolutionary new way ... called Virtual Finger, allows scientists to move through ... synapses using the flat surface of their computer ... studies orders of magnitude more efficient, saving time, ... many areas of experimental biology. The software and ...
(Date:7/10/2014)... 2014 Understanding the need for better ... and the gap that currently exists in this area, ... industry-leading portfolio of validated ion channel and GPCR cell ... lines, as ion channels control many critical physiological functions ... creates the potential to treat a variety of human ...
(Date:7/10/2014)... EvoDerma ’s NOOME Anti-Aging Motion has been ... comes with a second treatment cup to help prevent and ... cup is thinner on the edges for a softer contact ... and uneven surfaces on the face, neck and décolleté. Choose ... on areas such as the cheeks and neck, or opt ...
(Date:7/10/2014)... PROVO, Utah , July 10, 2014 ... genome annotation and interpretation, today announced an ... sequencing (NGS) analytics for Lineagen,s NextStep Dx ... evaluation of neurodevelopmental and neurological disorders, currently ... chromosomal microarray (CMA) testing service used by ...
Breaking Biology Technology:Virtual Finger Enables Scientists To Navigate And Analyze 3D Images Of Complex Biological Structures 2Virtual Finger Enables Scientists To Navigate And Analyze 3D Images Of Complex Biological Structures 3Leader in Ion Channel Research Announces Newly Validated and Re-Engineered Cells 2Leader in Ion Channel Research Announces Newly Validated and Re-Engineered Cells 3Introducing a New Bonus Treatment Cup for EvoDerma’s NOOME Anti-Aging Motion 2Tute Genomics Platform Selected to Provide Clinical Interpretation for Lineagen's NextStepDx PLUS Next-Generation Sequencing-Based Diagnostic Test 2Tute Genomics Platform Selected to Provide Clinical Interpretation for Lineagen's NextStepDx PLUS Next-Generation Sequencing-Based Diagnostic Test 3Tute Genomics Platform Selected to Provide Clinical Interpretation for Lineagen's NextStepDx PLUS Next-Generation Sequencing-Based Diagnostic Test 4
... Devgen,(Eurolist: DEVG) and Monsanto Company (NYSE: MON ... which Monsanto has agreed, subject to certain,customary conditions, to ... 18 million (25 million $) and representing 5.9%,of the ... take place,no later than November 2007. It is ...
... announces today,that a service agreement with Roche Diagnostics ... its automated immunohistochemistry,service platform for analyzing various biomarkers ... will provide for this project a selection of,tumor ... as specifically,collected clinical samples. The analysis of specific ...
... Nationally, SCOTTSDALE, Ariz., Sept. 14 CHS, an ... by the U.S. Department,of Defense as a recipient of ... award, sponsored by the National Committee of Employer,Support of ... honor,bestowed upon America,s employers who provide support to their ...
Cached Biology Technology:Monsanto Company Signs Share Subscription Agreement With Devgen 2Monsanto Company Signs Share Subscription Agreement With Devgen 3CHS Receives Prestigious Honor from Department of Defense 2CHS Receives Prestigious Honor from Department of Defense 3
... This kit allows for rapid, convenient, and ... simple bind/wash/elute process utilizes a spin column ... beads for concentration of proteins which were ... are strong ion exchangers, offering high binding ...
... angle system, 220-240 V, is used to resolve ... fragments by pulsed field gel electrophoresis (PFGE). The ... pump, 14 x 13 cm casting stand with ... thick comb, screened cap, disposable plug molds, 12 ...
... kit is designed to knockout or alter genes ... than one week. Red/ET recombination allows the exchange ... specific, and faithful manner. An FRT-flanked kanamycin resistance ... can be used to replace a gene on ...
... separation system using the asymmetric flow Field ... easily with Wyatts multi-angle light scattering (MALS) ... the Optilab DSP. The combined system provides ... the particles/molecules separated by the AFFF unit. ...
Biology Products: