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Louisville researcher awarded $12.8 million NIH grant renewal for adult stem cell project
Date:9/9/2011

At the time when Dr. Roberto Bolli received word that he was awarded a $12.8 million grant renewal from the National Institutes of Health for one research project, five patients in another of his clinical trials at the University of Louisville have reached the successful endpoint of their participation.

The National Heart, Lung and Blood Institute of the NIH has funded Bolli's program project grant, "Protection of Ischemic Myocardium" for five years. Originally funded at $11.7 million in 2006, the project involves research with adult stem cells in four areas:

  • Investigating how introducing genes into stem cells might improve stem cell therapies
  • Looking at how diabetes affects stem cells
  • Looking at how a class of proteins cytokines affect stem cells during heart failure
  • Investigating the signaling pathways of stem cells in the body

"UofL has a mandate to become a nationally recognized metropolitan research university. One gauge is our faculty's ability to attract competitive grant funding from the NIH," President James R. Ramsey said. "The fact that our program has been renewed during these very competitive times demonstrates yet again the high quality talent we have at UofL. Even more importantly, our faculty are turning research discoveries into medical treatments that enhance the lives of their patients."

Additionally, this grant application was the number one application nationwide in scoring by the NHLBI, going up against top universities in the country including Ivy League institutions. The overall score of the UofL application was the highest possible a "10" and each of the four component projects earned individual scores of "10."

An overall score of 10 is extraordinarily rare and NIH staff report to Bolli that they do not know of any other grant receiving scores of 10 for each project within a grant.

Bolli and his team have brought to UofL more than $100 million in NIH grants
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Contact: Jill Scoggins
jill.scoggins@louisville.edu
502-852-7461
University of Louisville
Source:Eurekalert  

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Louisville researcher awarded $12.8 million NIH grant renewal for adult stem cell project
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