Navigation Links
Looking for the Founatain of Youth? Cut your calories, research suggests
Date:7/3/2008

ST. LOUIS Want to slow the signs of aging and live longer? New Saint Louis University research suggests cutting back on calories could be a promising strategy.

Calorie restriction has long been shown to slow the aging process in rats and mice. While scientists do not know how calorie restriction affects the aging process in rodents, one popular hypothesis is that it slows aging by decreasing a thyroid hormone, triiodothyronine (T3), which then slows metabolism and tissue aging.

A new study in the June 2008 issue of Rejuvenation Research, found that calorie restriction cutting approximately 300 to 500 calories per day had a similar biological effect in humans and, therefore, may slow the aging process.

"Over recent years, there has been a huge amount of debate about whether calorie restriction slows the aging process in humans," said Edward Weiss, Ph.D., associate professor of nutrition and dietetics at Saint Louis University's Doisy College of Health Sciences and lead author of the study.

"Our research provides evidence that calorie restriction does work in humans like it has been shown to work in animals. The next step is to determine if this in fact slows age-related tissue deterioration. The only way to be certain, though, is to do a long-term study."

In the current study, Weiss wanted to know if calorie reduction would lower T3 levels in humans. To determine if the lowered levels of T3 were a result of calorie restriction and not decreases in fat mass in general, Weiss also recruited volunteers to lose weight through exercise.

Study volunteers included sedentary, non-smoking, 50- to 60- year-old men and post-menopausal women with average or slightly above average body man index values. They were in otherwise good health and did not have cardiovascular disease, diabetes, lung disease, uncontrolled hypertension and evidence of malignancy.

Volunteers were randomly assigned to one of three groups a calorie-restriction group, an exercise group or a control group and followed for one year. Volunteers in the calorie restriction group lost weight by reducing their daily calorie intake by 300 to 500 calories per day. Volunteers in the exercise group maintained their regular diet and exercised regularly.

Volunteers in both the calorie-restriction and exercise groups experienced similar changes of body fat mass. However, only volunteers in the calorie restriction group also experienced lower levels of the thyroid hormone.

Although a long-term study is still needed to determine if reducing T3 levels through calorie restriction does indeed slow the aging process, Weiss says cutting back on calories is a good idea.

"There is plenty of evidence the calorie restriction can reduce your risks for many common diseases including cancer, diabetes and heart disease," Weiss said. "And you may live to be substantially older."

When cutting calories, Weiss warns that it is imperative to maintain a healthy diet by eating nutrient-rich foods. Cutting 300 to 500 calories per day is equivalent to skipping dessert or substituting a turkey sandwich instead of a Big Mac and fries.

"Anorexia nervosa is a condition that is associated with calorie restriction that is far too severe and is accompanied by inadequate intakes of many nutrients. Consequently, it results in premature disease and even death, rather than improvements in health and a slowing of aging."

Because it also slows metabolism, Weiss warns that calorie-restricted weight loss could make people more prone to weight gain over time. On the other hand, people who lose weight through exercise are not as likely to gain weight back if they quit exercising. The key to maintaining a healthy weight, Weiss says, is keeping a consistent diet and exercising regularly.


'/>"/>

Contact: Sara Savat
ssavat@slu.edu
314-977-8018
Saint Louis University
Source:Eurekalert

Related biology news :

1. Looking through the eyes of a mouse, scientists monitor circulating cells in its bloodstream
2. Looking at neurons from all sides
3. Are you looking at me?
4. Research shows skeleton to be endocrine organ
5. Newly created cancer stem cells could aid breast cancer research
6. Dominant cholesterol-metabolism ideas challenged by new research
7. Researchers identify proteins involved in new neurodegenerative syndrome
8. Texas researchers and educators head for Antarctica
9. MGH researchers describe new way to identify, evolve novel enzymes
10. University of Pennsylvania researchers develop formula to gauge risk of disease clusters
11. University of Oregon researcher finds that on waters surface, nitric acid is not so tough
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/4/2017)... , Jan. 4, 2017  For the thousands of attendees at ... global leader in connected health and biometric measurement devices and services, will ... On display in A&D Medical,s special CES Exhibit Suite ... the ongoing expansion of the company,s WellnessConnected product platform.  ... ...
(Date:12/22/2016)... 20, 2016  As part of its longstanding mission to ... genetics company, recently released its latest children,s book, titled ... focuses on the topics of inheritance and variation of traits ... taught in elementary school classrooms in the US. ... illustrator Ariana Killoran , whose previous book with 23andMe, ...
(Date:12/20/2016)... N.C. and GENEVA, Dec, 20, 2016 /PRNewswire/ ... biometric data sensor technology, and STMicroelectronics ... the spectrum of electronics applications, announced today the ... development kit for biometric wearables that includes ST,s ... with Valencell,s Benchmark™ biometric sensor system. ...
Breaking Biology News(10 mins):
(Date:1/18/2017)... ... January 18, 2017 , ... Whitehouse Labs ... Within Albany Molecular Research, Inc. (AMRI), the scientific staff dedicated to Extractables / ... planned for further growth in 2017. Extractable & Leachable evaluations have become increasingly ...
(Date:1/18/2017)... OF PRUSSIA, PA (PRWEB) , ... January 18, ... ... disrupt clinical operations again at the CHI SCOPE Summit for Clinical Ops Executives ... AstraZeneca in engaging panel discussions to examine vital clinical research issues such as ...
(Date:1/18/2017)... , Jan. 18, 2017 Shareholder rights ... investigation into whether the board members of CoLucid Pharmaceuticals, ... duties in connection with the proposed sale of the ... biopharmaceutical company that develops small molecules for the acute ... CoLucid announced it had signed a definitive merger agreement ...
(Date:1/18/2017)... , Jan. 18, 2017  Market Research Future published a ... Market is expected to grow at a CAGR of 12% during ... ... caused due to the abnormal cell division without any control. These ... harm to them. These cancer cells can spread to other parts ...
Breaking Biology Technology: