Navigation Links
Looking for secrets to drug addiction in our blood
Date:9/17/2010

RICHLAND, Wash. -- A new collaboration between the Department of Energy's Pacific Northwest National Laboratory and the Air Force's 59th Medical Wing hopes to improve on drug tests for illicit drug use and abuse. Not only are the researchers looking for a better indicator of current or past use, but they'd like to be able to identify people prone to abusing drugs in the first place.

Funded by the Department of Defense, the $850,000 two-year study will lay the foundation for future work to determine who might be susceptible to hydrocodone. Initially, the collaboration will map out drug breakdown products, proteins and other compounds that healthy bodies make in response to the prescription painkiller hydrocodone.

"We want to enhance the prevention, diagnosis and treatment of drug addiction. Our military deserves the best care we can give them," said Lt. Col. (Dr.) Vikhyat Bebarta, a research physician in the 59th Medical Wing at Lackland Air Force Base near San Antonio, Texas. Bebarta will be co-leading the study with biochemist Josh Adkins of PNNL.

The results will likely extend beyond the military. "Any tools for drug addiction that come out of this study could also be used by the general public," said Adkins.

Just as some genes confer a susceptibility to alcoholism, the team hopes to find some indicator of susceptibility to dependence on painkillers such as hydrocodone. Instead of a gene, though, the researchers hope to find a difference in how a susceptible person responds to the drug, compared to a nonsusceptible one. If such an indicator exists in blood, urine or saliva, not only would it improve our understanding of the biological response to hydrocodone, but tests that reveal the indicator could be developed.

Dependency tendency

The painkiller hydrocodone is one of the most abused drugs in the U.S. Its use, abuse and addictive potential pose special concern for the armed forces, whose members
'/>"/>

Contact: Mary Beckman
mary.beckman@pnl.gov
509-375-3688
DOE/Pacific Northwest National Laboratory
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Seeing without looking
2. Looking for the heartbeat of cellular networks
3. Iowa State researchers looking for catalyst that allows plants to produce hydrocarbons
4. UAB researchers looking for genetic predictors for suicide
5. Case Western Reserve researchers looking at light-induced toxins in air and water
6. New satellite techniques for looking at climate change
7. Neutrons helping ORNL researchers unlock secrets to cheaper ethanol
8. Ancient brew masters tapped antibiotic secrets
9. Secrets of the gecko foot help robot climb
10. Frozen flies may yield secrets for human organ transplants
11. Unlocking the secrets of RNA biology with WIREs
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/22/2014)... Dec. 22, 2014 Research and Markets ... the addition of the "The Global ... their offering. ... an overview of the global digital media ... control and monitor piracy by securely and ...
(Date:12/19/2014)... 2014   LaunchKey , the first decentralized mobile ... Internet of Things era, today announced the close of ... was led by Metamorphic Ventures with participation from ENIAC ... and others.  LaunchKey has raised $4 million to date, ... team and bring LaunchKey to market in 2015. ...
(Date:12/17/2014)... --Research and Markets ( http://www.researchandmarkets.com/research/9zq33j/global_chemical ) ... Chemical Sensor Market 2015-2019" report to their ... One major trend upcoming in this ... in biomedical applications. Chemical sensors help in recording ... during surgical procedures. The Global Chemical Sensor market ...
Breaking Biology News(10 mins):The Global Watermarking and Fingerprinting Markets 2LaunchKey Raises $3 Million in Additional Funding Led by Metamorphic Ventures 2LaunchKey Raises $3 Million in Additional Funding Led by Metamorphic Ventures 3Global Chemical Sensor Market 2015-2019: Key Vendors are Abbott Laboratories, Bayer, Hoffmann La-Roche, Johnson & Johnson, NGK Spark Plugs and Robert Bosch 2
... There,s currently no reliable tool to help prosthetic developers ... medical personnel when bed-ridden patients need to be moved to ... now on the way. Prof. Amit Gefen of Tel Aviv ... a new device he calls the Soft Tissue Stress Monitor, ...
... and WEST PALM BEACH, Fla. , ... of authentication and endpoint protection solutions and ScriptRx, a ... Discharge Systems for Emergency Rooms and Urgent Care Centers, ... DigitalPersona into the ScriptRx System. Designed for these busy ...
... variant of a receptor in the brain,s reward circuitry ... dopamine is released in the brain following alcohol intake, ... National Institute on Alcohol Abuse and Alcoholism (NIAAA), part ... involved in transmitting the euphoria and other positive subjective ...
Cached Biology News:Finding the soft spot 2ScriptRx and DigitalPersona Team Up to Secure Emergency Room and Urgent Care Electronic Medical Records 2ScriptRx and DigitalPersona Team Up to Secure Emergency Room and Urgent Care Electronic Medical Records 3ScriptRx and DigitalPersona Team Up to Secure Emergency Room and Urgent Care Electronic Medical Records 4Receptor variant influences dopamine response to alcohol 2
(Date:12/24/2014)... The report provides basic ... definition, classification, application and industry overview. This ... and product cost structure. Production is separated ... also covers upstream raw materials, equipment, downstream ... and proposals. In the end, the export ...
(Date:12/24/2014)... 2014 China Biologic Products, Inc. (NASDAQ: ... fully integrated plasma-based biopharmaceutical company in ... subsidiary, Shandong Taibang Biological Products Co. Ltd., has ... China Food and Drug Administration (the "CFDA") for ... disclosed in the Company,s public filings, the CFDA ...
(Date:12/24/2014)... , Dec. 23, 2014  Rock Creek Pharmaceuticals, ... it has filed a Clinical Trial Application (CTA) with ... products Regulatory Agency (MHRA) seeking regulatory approval to initiate ... molecule, Anatabine Citrate. Contingent on the Company ... a Phase I trial to assess the safety, tolerability ...
(Date:12/22/2014)... 2014 /PRNewswire/ - RepliCel Life Sciences Inc. (OTCQB: REPCF) ... on the development of autologous cell therapies, announced today ... of Calgary in conjunction with co-authors from Kyoto University ... the company,s ongoing clinical research using dermal sheath cup ... The paper entitled " Hair Follicle Dermal ...
Breaking Biology Technology:Worldwide Methyl Mercaptan Market 2015-2020 Forecasts on Development & Trends Now Available at ReportsnReports.com 2China Biologic Receives GMP Certification for New Coagulation Factor Facility 2China Biologic Receives GMP Certification for New Coagulation Factor Facility 3Rock Creek Pharmaceuticals Files Clinical Trial Application in the UK for Clinical Trials of Anatabine Citrate Formulations 2Rock Creek Pharmaceuticals Files Clinical Trial Application in the UK for Clinical Trials of Anatabine Citrate Formulations 3Newly Released Peer-Reviewed Publication Further Validates RepliCel's Use of Dermal Sheath Cup Cells to Treat Pattern Baldness 2Newly Released Peer-Reviewed Publication Further Validates RepliCel's Use of Dermal Sheath Cup Cells to Treat Pattern Baldness 3Newly Released Peer-Reviewed Publication Further Validates RepliCel's Use of Dermal Sheath Cup Cells to Treat Pattern Baldness 4Newly Released Peer-Reviewed Publication Further Validates RepliCel's Use of Dermal Sheath Cup Cells to Treat Pattern Baldness 5
... Now it's easy to make your RNA free of genomic DNA , ... , & Removal Reagents contain RNase-free DNase, ... to ensure safe, complete removal of , ... DNase Removal Reagent which, after digestion, eliminates DNase in , ...
... , ... RT-PCR and microarray gene expression analysis , ... no grinding or polytron required , ... tissue lysates , Faster and easier ...
... Low transfection efficiency and low cell , ... causes of unsuccessful gene , ... choosing the right transfection agent and transfection , ... in many cell types. Once a protocol is optimized ...
Cached Biology Technology:DNA-free A NEW Method to Remove DNA 2DNA-free A NEW Method to Remove DNA 3DNA-free A NEW Method to Remove DNA 4DNA-free A NEW Method to Remove DNA 5DNA-free A NEW Method to Remove DNA 6DNA-free A NEW Method to Remove DNA 7DNA-free A NEW Method to Remove DNA 8Hands-free Tissue Disruption No Homogenization Needed 2Hands-free Tissue Disruption No Homogenization Needed 3Hands-free Tissue Disruption No Homogenization Needed 4Hands-free Tissue Disruption No Homogenization Needed 5Hands-free Tissue Disruption No Homogenization Needed 6Hands-free Tissue Disruption No Homogenization Needed 7Optimizing siRNA Transfection for RNAi 2Optimizing siRNA Transfection for RNAi 3Optimizing siRNA Transfection for RNAi 4Optimizing siRNA Transfection for RNAi 5Optimizing siRNA Transfection for RNAi 6Optimizing siRNA Transfection for RNAi 7Optimizing siRNA Transfection for RNAi 8Optimizing siRNA Transfection for RNAi 9Optimizing siRNA Transfection for RNAi 10Optimizing siRNA Transfection for RNAi 11
... developed specifically for the stabilization of ... plates/strips. Coating Stabilizer maintains the ... or protein antigen portion of the ... filtered at 0.2 microns., ,Contents: ...
Yeast tRNA 50 l...
...
... Low volume pipetting is increasingly ... volumes in DNA sequencing and other ... with performance and precision unparalleled in ... documented confirmation of all aspirated,and dispensed ...
Biology Products: