Navigation Links
Longevity mutation found in flies far and wide
Date:2/5/2014

r to affect the concentration of these nutrients in the cell, effectively mimicking the effect of living on a calorie-restricted diet. Calorie restriction and certain Indy mutations have been shown to extend life span in flies and nematodes.

The hypothesis the scientists pursued is that mutations in Indy regulate the expression of the normal Indy gene, thereby leading to changes in the level of Indy activity in the body for better or worse. For that reason, the researchers measured levels of mRNA (the molecular means by which genes are expressed) in the flies. The more Hoppel insertion there was, they found, the more Indy expression there was. Heterozygotes lived longest and laid the most eggs, suggesting that the best level of expression might be the moderate one.

That the transposable element appears to confer benefits is a very exciting finding, Helfand said.

"It has often been suggested that the insertion of transposable elements into genes are largely detrimental to the organism," he said. "The present study is one of the few documented cases demonstrating insertion of a transposable element to have a positive benefit for the organism. Furthermore, it suggests that mutations due to transposable element insertion into genes may represent one of the ways by which new genetic material is produced, providing the raw material for natural selection and adaptive evolution."


'/>"/>
Contact: David Orenstein
david_orenstein@brown.edu
401-863-1862
Brown University
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. New study finds extreme longevity in white sharks
2. Why cells stick: Phenomenon extends longevity of bonds between cells
3. Dopamine-receptor gene variant linked to human longevity
4. Gladstone scientists discover novel mechanism by which calorie restriction influences longevity
5. Personality genes may help account for longevity
6. Horse gaits controlled by genetic mutation spread by humans, new study reveals
7. New hope: Researchers discover genetic mutations that cause rare and deadly lung disease
8. Mutation discovery may improve treatment for rare brain tumor type
9. Important mutation discovered in dairy cattle
10. Scientists identified T372R mutation as potential target for diagnosis and treatment of insulinoma
11. Genetic mutation may play key role in risk of lethal prostate cancer in overweight patients
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Longevity mutation found in flies far and wide
(Date:3/24/2015)... BEACH GARDENS, Fla. , March 24, 2015 ... biometric identity management solutions, today announced that its ... premium clothing accessory retailer Goorin Bros . ... The Crossmatch biometrics-based solution secures access to the ... from the increased risk of data breaches. ...
(Date:3/20/2015)... DUBLIN , Mar. 20, 2015 Research ... announced the addition of the "India Sensors ... their offering. The sensor market is ... through 2020 Consumer electronics, automotive, industrial ... for sensors in the country. In addition, adoption ...
(Date:3/18/2015)... , March 18, 2015 As ... businesses, new revolutionary smart wallets and apps continue to be ... currently entrenched in the mobile payment industry in focus today ... Holding Ltd. (NYSE: BABA ), Apple Inc. (NASDAQ: ... ) and Facebook Inc. (NASDAQ: FB ) ...
Breaking Biology News(10 mins):Crossmatch Fingerprint Readers Help Retailer Prevent Data Breaches at Point-of-Sale 2India Sensors Market Forecast and Opportunities 2020 - STMicroelectronics held the largest share in 2014 2India Sensors Market Forecast and Opportunities 2020 - STMicroelectronics held the largest share in 2014 3Revolutionary Smart Wallet & Mobile Payment Choices Change the Game for Consumers - Company Begins Shipping Newest Digital Wallet to Customers 2Revolutionary Smart Wallet & Mobile Payment Choices Change the Game for Consumers - Company Begins Shipping Newest Digital Wallet to Customers 3Revolutionary Smart Wallet & Mobile Payment Choices Change the Game for Consumers - Company Begins Shipping Newest Digital Wallet to Customers 4Revolutionary Smart Wallet & Mobile Payment Choices Change the Game for Consumers - Company Begins Shipping Newest Digital Wallet to Customers 5Revolutionary Smart Wallet & Mobile Payment Choices Change the Game for Consumers - Company Begins Shipping Newest Digital Wallet to Customers 6
... study mapping the evolutionary history of animals indicates that ... be inferred from fossils and studies of living animals--was ... The study, which was funded by the National Science ... 10, 2008 issue of Nature. Using new high-powered technologies ...
... broad range of genetic tests. Paternity tests at ... baldness. With ongoing genetic discoveries and technology ... before and along with greater availability has come ... can consumers make informed decisions about genetic tests" ...
... play an important role in preventing lake trout from ... should be a priority, Montana State University researchers said ... Park workers might have to remove ice, logs or ... barriers, said graduate student Michael Meeuwig and his adviser ...
Cached Biology News:And the first animal on Earth was a ... 2And the first animal on Earth was a ... 3American College of Medical Genetics makes genetic testing recommendations in new policy statement 2Montana State researchers study spread of lake trout in Glacier National Park 2
(Date:3/26/2015)... , March 26, 2015 /PRNewswire/ - SQI Diagnostics Inc. ... that after dealing with certain matters, including the appointment ... held on March 26, 2015 (the "Meeting") was adjourned, ... 8, 2015 at 11:00 a.m. ( Toronto ... been changed from that previous disclosed. The Meeting will ...
(Date:3/26/2015)... Neogen Corporation (NASDAQ: NEOG ) announced today that ... 2015, which ended Feb. 28, increased 13% to $7,454,000, ... share in the current quarter were $0.20, compared to ... 17% over prior year to $24,142,000, or $0.65 per ... the same period a year ago. Revenues ...
(Date:3/26/2015)... Ale Gicqueau, Founder and President of Clinovo, will ... Align Technology, on “ Conducting Postmarket Registries - Rationale ... Conference and Exhibition on April 25th through April 28th ... poster presentation, Ale Gicqueau and Victor Chen will discuss ... the requirements and resources to conduct the registry, as ...
(Date:3/25/2015)... - SQI Diagnostics Inc. ("SQI" or the "Company") (TSX-V: SQD; ... discussions with certain shareholders representing approximately 45% of the ... with certain matters including the appointment of auditors at ... 26, 2015 (the "Meeting") it intends to adjourn the ... place when the Meeting reconvenes. The Meeting will be ...
Breaking Biology Technology:SQI Diagnostics Inc. Announces Adjournment of Meeting 2Neogen reports 13% increase in net income 2Neogen reports 13% increase in net income 3Neogen reports 13% increase in net income 4Neogen reports 13% increase in net income 5Neogen reports 13% increase in net income 6Neogen reports 13% increase in net income 7Neogen reports 13% increase in net income 8Clinovo Presents at ACRP 2015 in Salt Lake City, Utah on April 25th-28th 2Clinovo Presents at ACRP 2015 in Salt Lake City, Utah on April 25th-28th 3SQI Diagnostics Inc. Announces New Nominees to SQI Diagnostics Board and Adjournment of Meeting 2SQI Diagnostics Inc. Announces New Nominees to SQI Diagnostics Board and Adjournment of Meeting 3SQI Diagnostics Inc. Announces New Nominees to SQI Diagnostics Board and Adjournment of Meeting 4SQI Diagnostics Inc. Announces New Nominees to SQI Diagnostics Board and Adjournment of Meeting 5
... , , , , , , Multiporator , , , ... Transfection Protocol , Protocol No. 4308 915.021 11/1999 , ... , , , ... , Transfection with , Plasmid pEGFP-N1 (in bidistilled H ...
... , , , , , , Multiporator / Electroporator 2510 , , ... , Transformation Protocol , Protocol No. 4308 ... , , , , , , ... , , Cell type , ...
... , , , , , , Multiporator / Electroporator 2510 , , ... , Transformation Protocol , Protocol No. ... , , , , , , ... , , Cell type , ...
Cached Biology Technology:NIH 3T3 2Mycobacterium smegmatis 2Mycobacterium avium 2
... specific for human cardiac troponin subunit T, a ... responsible for contraction of cardiac muscle. It reacts ... human cells. It also cross-reacts with human skeletal ... Antigen: Highly purified human cardiac troponin T ...
... White lyophilized solid. PROTECT FROM LIGHT. ... inhibitor of γ-secretase. Equipotently inhibits the release ... = 2.6 μM) and Aβ x-42 ... HEK293 cells stably transfected with the Amyloid ...
cystatin A (N-18)...
...
Biology Products: