Navigation Links
Longevinex exerts greater influence over genes than resveratrol
Date:12/27/2010

ypoxia inducing factor, or HIF-1 alpha) that adapts malignant cells to a low oxygen environment. MicroRNA 20b also exhibits control over growth factors (such as vascular endothelial growth factor, aka VEGF). The strong silencing (switching off) of HIF-1 alpha via microRNA 20b would be desirable, for example, to inhibit formation of new blood vessels that feed tumors and which invade the retina at the back of the eyes.

Prior to an induced heart attack, microRNA 21 was tremendously up-regulated (up 391.4-fold) by resveratrol and Longevinex (up 760.9-fold), was lowered considerably after a heart attack (-4.0), then returned to up-regulation following a heart attack by resveratrol (up 61.5) and Longevinex (up 59.3), which suggests protective pre-conditioning prior to the event.

MicroRNA 539 exhibited the highest level of up-regulation (214 fold) following a heart attack, which suggests a protective response. Resveratrol diminished this response (down from 214-fold to 172.4 fold) while Longevinex further enhanced this microRNA response, from 214-fold to 314.6-fold increase. MicroRNA 539 controls of a number of genes involved in healing heart tissue following a heart attack.


'/>"/>

Contact: Bill Sardi
bsardi@aol.com
909-596-9507
Resveratrol Partners LLC, dba LONGEVINEX
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Over 1,000 species discovered in the Greater Mekong in past decade
2. Genetic differences between yeasts greater than those between humans and chimpanzees
3. Lower increases in global temps could lead to greater impacts than previously thought, study finds
4. Scots and Irish at greater risk of drink-related death, study shows
5. Food insecurity can lead to greater weight gain and complications during pregnancy
6. Small mammals -- and rest of food chain -- at greater risk from global warming than thought
7. Children born after assisted reproduction at greater risk of congenital malformations
8. Greater food insecurity from recession poses increased risk to low income individuals with diabetes
9. New report suggests why risk for sudden infant death syndrome is greater in babies of mothers who smoke
10. Faster water flow means greater diversity of invertebrate marine life
11. Late-preterm babies at greater risk for problems later in childhood
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/22/2014)... USA More than 7,000 geoscientists will gather in ... The Geological Society of America,s 126th Annual Meeting & ... such topics as the transportation of crude oil, earthquake ... dedicated field guide, Trials and Tribulations of Life on ... around the Vancouver area. , A broad range of ...
(Date:9/21/2014)... Diego, have developed a program that predicts the placement ... based on sequences of DNA. They describe their analysis ... cells in a paper published in Nature Methods ... have the same blueprint, the same DNA, although they ... the report. "Skin cells protect, nerve cells send signals, ...
(Date:9/19/2014)... Durante of dinosaurs a newly discovered hadrosaur ... dinosaur, named Rhinorex condrupus by paleontologists ... University, lived in what is now Utah approximately ... period. , Rhinorex, which translates roughly into "King ... of other Cretaceous hadrosaurs like Parasaurolophus and Edmontosaurus. ...
Breaking Biology News(10 mins):Geoscience topics in the spotlight -- Vancouver, BC 2Geoscience topics in the spotlight -- Vancouver, BC 3Geoscience topics in the spotlight -- Vancouver, BC 4Geoscience topics in the spotlight -- Vancouver, BC 5Program predicts placement of chemical tags that control gene activity 2New hadrosaur noses into spotlight 2
... [Brown University] From a biological point of view, the ... by fungi. As a kingdom, they are full of surprises, ... seems sure to titillate the intellects of those who ... chromosomes in each cell. Fungal fecundity is a seemingly ...
... the United States National Museum of Natural History and ... researchers have found 16 new species of wasps from ... The new species are described and illustrated in ... Key of the Charipinae (Hymenoptera: Cynipoidea: Figitidae) From the ...
... activities "diluted" in the cell nucleus. In this state it ... tangle of thread, in actual fact its structure is governed ... out its functions. Biologists have studied DNA by observing it ... been supplemented by research in silico, that is to say, ...
Cached Biology News:Yeast's lifestyle couples mating with meiosis 2Yeast's lifestyle couples mating with meiosis 325 years of DNA on the computer 2
(Date:9/22/2014)... Texas (PRWEB) September 22, 2014 This ... state of the M-Phenylenediamine (mPDA) industry in Global ... the industry, including definitions, applications and industry chain structure. ... provided with a focus on history, developments, trends and ... international and Chinese situation is also offered. , The ...
(Date:9/22/2014)... Research and Markets has announced ... Cellulose Industry Report 2014" report to their offering. ... Industry Report 2014 is a professional and in-depth study ... industry with a focus on the Chinese situation. ... industry including definitions, classifications, applications and industry chain structure. ...
(Date:9/22/2014)... 22, 2014  WIRB-Copernicus Group (WCG), the world,s ... for clinical research, announced today that its Western ... reaccredited by the Association for the Accreditation of ... improve safeguards for clinical research participants. ... , Ph.D., commented, "It is of utmost importance ...
(Date:9/21/2014)... in Switzerland have succeeded in observing the "forbidden" ... first time. These extremely weak spectra offer perspectives ... may also contribute to the development of molecular ... in the scientific journal Nature Physics . ... matter and light, is probably the most important ...
Breaking Biology Technology:m-Phenylenediamine Industry: mPDA Global & China Trend Analysis Now Available at ReportsnReports.com 2m-Phenylenediamine Industry: mPDA Global & China Trend Analysis Now Available at ReportsnReports.com 3Global and Chinese Microcrystalline Cellulose Industry Report 2014 2Western IRB (WIRB) Awarded AAHRPP Reaccreditation 2Uncovering the forbidden side of molecules 2
... Md., June 27, 2011 PharmAthene, Inc. (NYSE Amex: ... achieved an important technical milestone in its recombinant protective ... initial technology transfer of its manufacturing process for the ... the 100 liter scale to a US-based manufacturing facility ...
... DIEGO, June 27, 2011 AltheaDx, ... "NGS" services into its clinical molecular pathology lab for ... intends to utilize NGS for both monitoring known and ... types.   "The addition of NGS greatly ...
... June 27, 2011 MedeAnalytics, a leading provider ... launch of its Patient Access Resource Center. Created ... end of the revenue cycle, the resource center ... and industry trends, as well as best-practice tools ...
Cached Biology Technology:PharmAthene Achieves Anthrax Vaccine Program Milestone and Successfully Completes Technology Transfer 2PharmAthene Achieves Anthrax Vaccine Program Milestone and Successfully Completes Technology Transfer 3AltheaDx Incorporates Next-Generation Sequencing Into Its Clinical Testing Pipeline. 2AltheaDx Incorporates Next-Generation Sequencing Into Its Clinical Testing Pipeline. 3
... The flexible and easy to ... to control all members of ... It features a clear and ... assay setup, user-friendly and highly ...
... Recombinant Enterokinase (rEK) is a highly ... bovine enterokinase, a serine protease which recognizes ... enzyme (AspAspAspAspLys?) and has similar enzymatic activity ... coli and purified to yield the highest ...
Roll of Mesh 5m x 25cm...
Angiotensin Converting Enzyme [Porcine Kidney, ACE, Peptidyl-dipeptidase A]...
Biology Products: