Navigation Links
Long-term use of certain contraception injections associated with increased fracture risk

A new study presented today at the World Congress on Osteoporosis (IOF WCO-ECCEO10) in Florence, Italy shows that DMPA, a commonly used injectible contraceptive, is associated with higher risk of bone fracture when used alone, and not in combination with estrogens.

Depot medroxyprogesterone acetate (DMPA) is a progestin-only long acting reversible hormonal contraceptive birth control drug which is injected every 3 months. It is used by more than 9 million women worldwide, with high usage among teenagers in Europe and the US. Previous studies have shown that use of DMPA is associated with impaired bone acquisition during adolescence and accelerated bone loss later in life, mainly in younger women with lower estrogen levels. However, few studies have looked into the impact of DMPA on fracture risk.

The study, conducted by researchers at the University Hospital Basel, Switzerland and the Boston University Medical Center, Lexington, USA, used a case-control analysis to evaluate the relationship between long-term use of DMPA, with or without estrogen, and the risk of fractures. The results show that in women below 50 years of age, longer-term use of DMPA of two and more years is associated with a 50% increased risk of fracture. For users of combined estrogen-containing oral contraceptives fracture risk was not increased.


Contact: L. Misteli
International Osteoporosis Foundation

Page: 1

Related biology news :

1. Meth exposure in young adults leads to long-term behavioral consequences
2. Tropical crab invades Georgia oyster reefs -- but the long-term impact cant be predicted
3. Atomic bomb survivor, scientists mark 60 years of long-term radiation study
4. Novel mechanism for long-term learning identified by Carnegie Mellon researchers
5. Long-term use of mechanical ventilation contributes to the deterioration of human diaphragm muscle
6. Ibuprofen or acetaminophen in long-term resistance training increases muscle mass/strength
7. Forests long-term potential for carbon offsetting
8. New vaccine may give long-term defense against deadly bird flu and its variant forms
9. Cancer immunotherapy shows long-term promise in lung cancer
10. Study of marine snail leads to new insights into long-term memory
11. Dont count on long-term success in climate policy, warns paper in Decision Analysis
Post Your Comments:
(Date:5/9/2016)... , UAE, May 9, 2016 ... when it comes to expanding freedom for high net ... Even in today,s globally connected world, there is ... conferencing system could ever duplicate sealing your deal with ... obtaining second passports by taking advantage of citizenship via ...
(Date:4/26/2016)... and LONDON , April 26, ... of EdgeVerve Systems, a product subsidiary of Infosys ... announced a partnership to integrate the Onegini mobile ...      (Logo: ) ... customers enhanced security to access and transact across ...
(Date:4/15/2016)... Research and Markets has announced ... 2016-2020,"  report to their offering.  , ... global gait biometrics market is expected to grow ... 2016-2020. Gait analysis generates multiple variables ... to compute factors that are not or cannot ...
Breaking Biology News(10 mins):
(Date:6/27/2016)... ... June 27, 2016 , ... ... Amgen, will join the faculty of the University of North Carolina Kenan-Flagler ... of strategy and entrepreneurship at UNC Kenan-Flagler, with a focus on the school’s ...
(Date:6/24/2016)... ... , ... While the majority of commercial spectrophotometers and fluorometers use the z-dimension ... are higher end machines that use the more unconventional z-dimension of 20mm. Z-dimension ... bottom of the cuvette holder. , FireflySci has developed several Agilent flow cell ...
(Date:6/23/2016)... - FACIT has announced the creation of a ... Propellon Therapeutics Inc. ("Propellon" or "the Company"), to ... of first-in-class WDR5 inhibitors for the treatment of ... an exciting class of therapies, possessing the potential ... patients. Substantial advances have been achieved with the ...
(Date:6/23/2016)... 23, 2016  The Biodesign Challenge (BDC), a university ... to harness living systems and biotechnology, announced its winning ... New York City . ... showcased projects at MoMA,s Celeste Bartos Theater during the ... MoMA,s senior curator of architecture and design, and ...
Breaking Biology Technology: