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Little but lethal -- small RNAs coordinate bacterial attack on epithelial cells
Date:1/13/2014

more complicated than they initially appeared," comments Petr G. Leiman at cole Polytechnique Fdrale de Lausanne in Switzerland. "Studies involving sRNA are tricky and require many controls which this paper appears to present in full, thus making the Sperandio team's work very significant."

"The horizontal acquisitions of pathogenicity islands [such as LEE] with their added virulence genes enable bacteria to exploit additional niches and new hosts," explains Sperandio. "Our results suggest that the interplay between ancient and recent evolutionary acquisitions shaped the EHEC we're dealing with today," Gruber adds. However, the evolution is ongoing and as the Red Queen in Alice in Wonderland so famously said, we have to race ahead just to keep up.


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Contact: Jim Sliwa
jsliwa@asmusa.org
202-942-9297
American Society for Microbiology
Source:Eurekalert

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