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Listeria clever at finding its way into bloodstream, causing sickness
Date:10/25/2010

o introduced listeria to intestinal cells in the upper half of a dual-chamber container and counted the number of bacteria that passed through the cells and appeared in the lower chamber.

The bacteria moved to the lower chamber faster than it is known to do when moving through cells, and did so even when a mutant form of the bacteria that do not invade the intestinal cells was used. This suggests the bacteria are moving around the cells, Bhunia said.

"The infective dose is very low. Even 100 to 1,000 listeria cells can cause infection," Bhunia said. "We believe that these mechanisms are what allow listeria to cause infections at such low levels."

Bhunia said he next would try to understand how listeria and the heat shock 60 protein interact and work to develop methods to protect intestinal cells from the bacteria. The Center for Food Safety Engineering at Purdue funded part of the research.


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Contact: Brian Wallheimer
bwallhei@purdue.edu
765-496-2050
Purdue University
Source:Eurekalert  

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