Navigation Links
Liquid crystal phases of tiny DNA molecules point up new scenario for first life on Earth
Date:11/22/2007

stal droplets, selectively developing into long molecules.

Liquid crystals -- organic materials related to soap that exhibit both solid and liquid properties -- are commonly used for information displays in computers, flat-panel televisions, cell phones, calculators and watches. Most liquid crystal phase molecules are rod-shaped and have the ability to spontaneously form large domains of a common orientation, which makes them particularly sensitive to stimuli like changes in temperature or applied voltage.

RNA and DNA are chain-like polymers with side groups known as nucleotides, or bases, that selectively adhere only to specific bases on a second chain. Matching, or complementary base sequences enable the chains to pair up and form the widely recognized double helix structure. Genetic information is encoded in sequences of thousands to millions of bases along the chains, which can be microns to millimeters in length.

Such DNA polynucleotides had previously been shown to organize into liquid crystal phases in which the chains spontaneously oriented parallel to each other, he said. Researchers understand the liquid crystal organization to be a result of DNAs elongated molecular shape, making parallel alignment easier, much like spaghetti thrown in a box and shaken would be prone to line up in parallel, Clark said.

The CU-Boulder and University of Milan team began a series of experiments to see how short the DNA segments could be and still show liquid crystal ordering, said Clark. The team found that even a DNA segment as short as six bases, when paired with a complementary segment that together measured just two nanometers long and two nanometers in diameter, could still assemble itself into the liquid crystal phases, in spite of having almost no elongation in shape.

Structural analysis of the liquid crystal phases showed that they appeared because such short DNA duplex pairs were able to stick together end-to-end, f
'/>"/>

Contact: Noel Clark
noel.clark@colorado.edu
303-492-6420
University of Colorado at Boulder  
Source:Eurekalert

Page: 1 2 3 4

Related biology news :

1. Researchers develop liquid crystal pharmaceuticals to fight cancer and other diseases
2. Unveiling the structure of microcrystals
3. Clemson scientists shed light on molecules in living cells
4. New molecules discovered that block cancer cells from modifying cell DNA
5. Curry-derived molecules might be too spicy for colorectal cancers
6. New book presents methods to poke and prod individual molecules
7. e-Science points to pollution solutions
8. Salmon garnish points the way to green electronics
9. NIH awards UC $9 million grant to improve patient point-of-care technologies
10. Research points towards early cancer detection
11. New thoracic imaging approach can pinpoint underlying venous problems
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Liquid crystal phases of tiny DNA molecules point up new scenario for first life on Earth
(Date:8/20/2014)... Cancer Institute (HCI) at the University of Utah have ... encodes BCR-ABL, the unregulated enzyme driving the blood cancer ... Society, nearly 6,000 new cases of CML will be ... tyrosine kinase inhibitors (TKIs), target BCR-ABL and are effective ... but control it in a way that allows patients ...
(Date:8/20/2014)... Using population-based screening outcomes of approximately 3 million ... four researchers at the University of Massachusetts Medical School, ... (SCID) can be successfully implemented across public health newborn ... in the Aug. 20 issue of the Journal ... showed the rate of SCID in newborns is higher ...
(Date:8/20/2014)... of sunscreen and seawater signals a relaxing trip to ... idyllic beach vacation comes with an environmental hitch. When ... sea, they can become toxic to some of the ... many other marine animals. Their study appears in the ... Antonio Tovar-Sanchez and David Snchez-Quiles point out that other ...
Breaking Biology News(10 mins):Blueprint for next generation of chronic myeloid leukemia treatment 2Newborn screening expansion offers early diagnosis and treatment to infants with SCID 2Newborn screening expansion offers early diagnosis and treatment to infants with SCID 3
... TORONTO, ON Researchers from the University of Toronto and ... the genes in the fungus that causes Dutch Elm Disease. ... 30 million DNA letters for the fungus Ophiostoma ulmi ... online journal BMC Genomics , could help scientists figure ...
... recently voted to scrap the controversial discards policy, which ... fish waste back into the sea because they have ... could have a negative impact on some seabirds, which ... are increasingly reliant on their discards., But they say ...
... syndrome who wonder if stress aggravates their intestinal disorder, a ... all in their head. Researchers revealed that while ... and induces the intestinal inflammation that often leads to severe ... Stress has a way of suppressing an important component ...
Cached Biology News:Discards ban could impact seabird populations 2Study: Probiotics reduce stress-induced intestinal flare-ups 2
(Date:8/21/2014)... HONG KONG , Aug. 21, 2014  China Cord ... today announced its plan to release financial results for ... August 28, 2014, after market close in the US.  ... call at 8:00 a.m. ET on Friday, August 29, ... brief overview of the Company,s recent developments, followed by ...
(Date:8/21/2014)... St. Louis, MO (PRWEB) August 21, 2014 ... premier, full service biopharmaceutical contract development and manufacturing ... selected by Progenics Pharmaceuticals, Inc., an oncology company ... targeting and treating cancer, to manufacture the anti-prostate ... Progenics’ PSMA ADC product candidate. Under the ...
(Date:8/20/2014)... An analysis of patented university inventions licensed to ... path to commercialization. To open these roadblocks, the ... results during the discovery stage could lead to ... are frequently derived from discoveries made in university ... well known during clinical trials, which have a ...
(Date:8/20/2014)... California (PRWEB) August 20, 2014 ... develop and apply the most complete climate and ... and demanding climate change issues. , Eight national ... forces with the National Center for Atmospheric Research, ... the new effort. Other participating national laboratories include ...
Breaking Biology Technology:China Cord Blood Corporation to Report First Quarter of Fiscal 2015 Financial Results 2Gallus Enters Agreement with Progenics Pharmaceuticals, Inc. for Manufacture of Anti-PSMA Monoclonal Antibody 2Gallus Enters Agreement with Progenics Pharmaceuticals, Inc. for Manufacture of Anti-PSMA Monoclonal Antibody 3Early bottlenecks in developing biopharmaceutical products delay commercialization 2Early bottlenecks in developing biopharmaceutical products delay commercialization 3New Project Is the ACME of Addressing Climate Change 2New Project Is the ACME of Addressing Climate Change 3
... ST. LOUIS, May 16 Stereotaxis, Inc. (Nasdaq:,STXS), ... Officer, will,present at the Seventh Annual JMP Securities ... 2008 at 12:00 p.m. Pacific Time., Attendance ... audio,presentation will be webcast live and remain available ...
... shown that they can use a red blood cell ... , "It turns around the rules of nanotechnology, by ... assistant professor in the Department of Biomedical Engineering at ... student Chawin Ounkomol. , An atomic force microscope uses ...
... esophagus eliminated in 90 percent ... ... Inc., the,global technology leader for treating precancerous conditions of the,digestive tract, ... study were free of the highest-risk of Barrett,s,esophagus after having a ...
Cached Biology Technology:New Study Reports That Ablative Therapy With HALO360 Device Effectively Treats Highest-Risk Category of Barrett's Esophagus 2New Study Reports That Ablative Therapy With HALO360 Device Effectively Treats Highest-Risk Category of Barrett's Esophagus 3
... sealed isolation chamber provides a safe, ... sterile pharmaceuticals, in accord with USP-797 ... 100 (ISO 5) cleanliness conditions in ... IV rod and tilt-up front panel ...
... siRNA Tracker Intracellular Localization Kit with ... forward approach to directly label and ... an efficient yet non-destructive manner, for ... and functional inhibition of target gene ...
... The Label IT siRNA Tracker Intracellular ... provides a straight forward approach to ... your design, in an efficient yet ... experiments. Subcellular localization and functional inhibition ...
Selective media for Salmonella...
Biology Products: