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Liquid biopsy could improve cancer diagnosis and treatment
Date:9/30/2013

material in each cell is often so small that it's hard to develop molecular assays," Wicha said. "This device allows the cells to be grown into larger quantities so you can do a genetic analysis more easily."

The chip could capture pancreatic, breast and lung cancer cells from patient samples. Nagrath was surprised that the device was able to catch about four tumor cells per milliliter of blood from the lung cancer patients, even though they had the early-stage form of the disease.

Working in a team that comprises both engineers and medical professionals at U-M, Nagrath is optimistic that the new technique could reach clinics in three years.

The paper is titled "Sensitive capture of circulating tumor cells by functionalized graphene oxide nanosheets." The university is pursuing patent protection for the intellectual property and is seeking commercialization partners to help bring the technology to market.


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Contact: Kate McAlpine
kmca@umich.edu
734-763-4386
University of Michigan
Source:Eurekalert

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