Navigation Links
Light can detect pre-cancerous colon cells
Date:10/11/2011

DURHAM, N.C. After demonstrating that light accurately detected pre-cancerous cells in the lining of the esophagus, Duke University bioengineers turned their technology to the colon and have achieved similar results in a series of preliminary experiments.

This technology could be a non-invasive way for physicians to detect abnormal cells, or dysplasia, which have the potential of turning cancerous. These cells are in the epithelium, or lining, of various tissues, including the esophagus and colon.

Current biopsy techniques require physicians to take many random tissue samples, and for some disorders of the colon, these procedures can be disfiguring and life-changing. Instead of taking tissue samples, the new system would aim short bursts of light from the tip of an endoscope at locations suspected of having disease.

"When light is directed at these tissues, it scatters," said Adam Wax, Theodroe Kennedy associate professor of biomedical engineering at Duke's Pratt School of Engineering, who developed the device. The results of the Duke team's preliminary experiments were reported online in the Journal of Biomedical Optics. "We can collect and analyze that scattered light looking for the tell-tale signs of dysplasia. Significantly, the technique is noninvasive so no tissue is taken and no dyes or contrast agents are needed."

In particular, they are trying to spot characteristic changes within the cells of the epithelium. In the case of pre-cancerous cells, the nuclei are misshapen and larger than normal cells, and they scatter light in their own unique way.

"The important thing for clinicians is being able to detect these changes in the nuclei in cells just below the surface, which might not be detected by just looking at the lining of the colon through an endoscope alone," Wax said.

The technology that Wax and his team developed for cancer detection is known as angle-resolved low coherence interferom
'/>"/>

Contact: Richard Merritt
richard.merritt@duke.edu
919-660-8414
Duke University
Source:Eurekalert

Page: 1 2

Related biology news :

1. October 2008 GEOLOGY and GSA TODAY media highlights
2. Agricultural research highlighted in Houston
3. Atomic-resolution views suggest function of enzyme that regulates light-detecting signals in eye
4. Can genetic information be controlled by light?
5. AGU journal highlights -- Oct. 16, 2008
6. Scripps research team sheds light on immune system suppression
7. Study sheds new light on dolphin coordination during predation
8. Spotlight on cosmetic ingredients conference
9. Polarized light guides cholera-carrying midges that contaminate water supplies
10. Study sheds light on genetic differences that cause a childhood eye disease
11. Hydrogen tank lighter than battery
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/6/2015)... , May 6, 2015 LifeBEAM, a ... established helmet producer, announced today that they will expand ... the world,s first bio-sensing cycling helmet and the first ... in two new colors in order to give cyclists ... product. In addition, LifeBEAM and Lazer announced their plan ...
(Date:4/21/2015)... 2015 High crime rate, ... boosting access control systems market in Saudi ... recently published report by TechSci Research " Saudi Arabia Access ... control systems market in Saudi Arabia ... access control systems market in the Kingdom is growing ...
(Date:4/14/2015)... -- NXT-ID, Inc. (NASDAQ: NXTD ) ("NXT-ID" or ... growing mobile commerce market, announces that its Wocket® smart ... Design Awards under the category  ,Product Design – Technology,. ... are part of a global multi-disciplinary awards program. The ... marketplace, industry and judging panel. Winners will be announced ...
Breaking Biology News(10 mins):LifeBEAM and Lazer Announce Expanded Partnership in Bio-Sensing Sports Gear 2LifeBEAM and Lazer Announce Expanded Partnership in Bio-Sensing Sports Gear 3Saudi Arabia Access Control Systems Market to Touch USD1.2 Billion by 2020 Says TechSci Research 2Saudi Arabia Access Control Systems Market to Touch USD1.2 Billion by 2020 Says TechSci Research 3NXT-ID's Wocket Smart Wallet Nominated for 2015 New York Design Awards in 'Product Design- Technology' 2NXT-ID's Wocket Smart Wallet Nominated for 2015 New York Design Awards in 'Product Design- Technology' 3
... Chemists say they have identified a gene that appears to ... diabetes, also known as insulin-dependent or juvenile diabetes, a disease ... is on the rise worldwide. They described their findings, which ... gene therapy, today at the 229th national meeting of the ...
... International HapMap Consortium, boosted by an additional $3.3 million ... even more powerful map of human genetic variation than ... genes related to common diseases, such as asthma, cancer, ... launched in October 2002, the consortium set September 2005 ...
... (MRS) for the first time to examine energy production ... have found substantial energy deficits in failing hearts. , ... the Proceedings of the National Academy of Sciences, confirm ... failure, and suggest new treatments designed to reduce energy ...
Cached Biology News:Towards precise classification of cancers based on robust gene functional expression profiles 2Towards precise classification of cancers based on robust gene functional expression profiles 3International HapMap consortium expands mapping effort 2International HapMap consortium expands mapping effort 3International HapMap consortium expands mapping effort 4Special Imaging Study Shows Failing Hearts Are 'Energy Starved' 2
(Date:6/2/2015)... -- Research and Markets( http://www.researchandmarkets.com/research/l5jcdk/genotyping_market ) has announced the ... & by Products - Global Forecast to 2020" ... market is expected to reach $17.0 Billion in 2020 ... 22.3% during the forecast period of 2015 to 2020 ... availability of a range of products for wide applications, ...
(Date:6/2/2015)... --  BioClinica ® , Inc., a specialty clinical ... David Peters , an accomplished senior finance and accounting ... Financial Officer (CFO) and will be joining BioClinica on ... 25 years of financial and accounting experience with a ... knowledge in all areas of finance, accounting and business ...
(Date:6/2/2015)... , June 2, 2015  Alere Inc. (NYSE: ... diagnostics, joined the White House Antibiotic Stewardship Forum ... to support and advance the President,s National Action ... include a number of measurable goals and objectives ... will help healthcare providers protect their patients through ...
(Date:6/2/2015)... (PRWEB) June 02, 2015 GenoCAD ... synthesis to improve protein expression, announced the formation of ... six executives and entrepreneurs with a broad range of ... , The team includes: , Jimmy Roussel, Entrepreneur ... Roussel has a background in technology and marketing. He ...
Breaking Biology Technology:Genotyping Market Report 2015 by Technology, Application & by Products - Global Forecast to 2020 for the $17 Billion Market 2BioClinica Names David Peters New Chief Financial Officer 2Alere Announces Broad Initiatives to Help Combat Antibiotic Resistance during White House Antibiotic Stewardship Forum 2GenoCAD Announces New Board of Advisors, Improves Protein Expression Using Custom Gene Synthesis 2GenoCAD Announces New Board of Advisors, Improves Protein Expression Using Custom Gene Synthesis 3
... Reflects Emphasis on Drug Development and Recent ... Private ... Inc. (Nasdaq: LXRX ) announced several changes to the,composition ... development and the completion of a major strategic financing,with Invus, ...
... N.C., Sept. 25 DrScore.com, a nationwide,service ... their physicians,feedback online, announced today that it ... provides medical practices with free,practice-branded Web sites ... the terms of the partnership between DrScore ...
... Israel, Sept. 25 ,Monsanto Company (NYSE: MON ... collaboration to improve nitrogen use efficiency in corn, ... exclusive rights to,a number of genes discovered by ... of nitrogen. Monsanto will work to evaluate the ...
Cached Biology Technology:Lexicon Appoints Judith Swain, M.D. to Board of Directors 2Lexicon Appoints Judith Swain, M.D. to Board of Directors 3Lexicon Appoints Judith Swain, M.D. to Board of Directors 4DrScore.com Partners With Vivacare For Patient Education And Feedback 2Monsanto and Evogene Collaborate on Nitrogen Use Efficiency Research 2Monsanto and Evogene Collaborate on Nitrogen Use Efficiency Research 3
... analysis of gene expression) technology ... Expression profiles generated by SAGE ... low-abundance transcripts making it possible ... I-SAGE Kit is designed to ...
...
Human PDGF, CF...
... The mycobacteria in Complete Freund's adjuvant attract ... site which enhances the immuneresponse. For this ... for the initial injections; Incomplete Freund's adjuvant ... (preferably in saline) are typically mixed with ...
Biology Products: