Navigation Links
Life span of ovarian grafts longer than expected
Date:6/28/2012

Transplanting previously frozen ovarian tissue back into female cancer survivors can lead to long-term hormonal function and preservation of fertility, according to a new study by Samuel Kim from the University of Kansas Medical Center in the US. His work, which shows that hormonal function was restored in five women 12-20 weeks after transplantation, and in one case lasted for more than seven years, appears online in the Journal of Assisted Reproduction and Genetics, published by Springer.

Many female cancer patients want to remain fertile, and choose to freeze some of their ovarian tissue prior to cancer treatment. Following treatment, the frozen tissue is thawed and transplanted back into the survivor's body, in a different location - known as a 'heterotopic site'. However, the longevity of grafted ovarian tissue has been debated for many years, and it is still uncertain how long hormonal (endocrine) function of frozen-thawed ovarian tissue can be maintained.

Kim studied five cancer survivors who had undergone heterotopic ovarian transplantation between 2001-2011. Their frozen ovaries were rapidly thawed and transplanted into the abdominal region. Kim measured both the levels and function of the reproductive hormones in these women via monthly blood tests and ultrasounds after hormonal activity was confirmed. The women were monitored until cessation of hormonal function.

He found that hormonal function was restored in all five patients 12-20 weeks after transplantation. Long-term follow-up in four patients showed that these women needed a second transplantation within two years of the first. Interestingly, restoration of ovarian function after the second transplantation was faster and lasted longer, between nine months and seven years.

The longest duration of hormonal function was seen in a 28-year-old women who underwent ovarian transplantation in 2003 and 2004 after radiotherapy for cervical cancer. Even seven ye
'/>"/>

Contact: Joan Robinson
joan.robinson@springer.com
49-622-148-78130
Springer
Source:Eurekalert

Page: 1 2

Related biology news :

1. Researchers identify genes that may help in ovarian cancer diagnosis and prognosis
2. Longer sleep times may counteract genetic factors related to weight gain
3. Pain relief with PAP injections may last 100 times longer than a traditional acupuncture treatment
4. Global Surgical Devices Market Growth Driven by Improving Standards of Living and Longer Life Expectancies, Research Shows
5. Study suggests why some animals live longer
6. The millennium-old olive trees of the Iberian Peninsula are younger than expected
7. Unexpected discovery reveals a new mechanism for how the cerebellum extracts signal from noise
8. Unexpected crustacean diversity discovered in northern freshwater ecosystems
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/9/2014)... Spanish National Cancer Research Centre (CNIO) have discovered that ... regulates cell division in stratified epitheliathose that form part ... oesophagus or the vaginain adult organisms. According to the ... Nature Communications , this factor could also play a ... epithelia of the oesophagus and skin. , The pluripotency ...
(Date:7/9/2014)... 9, 2014Biofuels derived from the oils produced by algae ... To achieve this goal, optimization of cost effective strategies ... systems, is needed. Sapphire Energy has developed an innovative ... algae cultivation systems, described in Industrial Biotechnology , ... The article is available on the Industrial Biotechnology ...
(Date:7/9/2014)... the prevalence of antibiotic-resistant illness, Case Western Reserve ... disabling disease: blocking bacteria,s access to iron in ... siderophore, a small molecule, captures iron from two ... as well as how the body launches a ... appear in a recent edition of The ...
Breaking Biology News(10 mins):CNIO scientists discover that pluripotency factor NANOG is also active in adult organisms 2Controlling contamination in open algae ponds for biofuels 2Bacteria hijack plentiful iron supply source to flourish 2
... by intestinal worms a condition that affects more than ... immune system is more versatile than has long been thought. ... exploration in the search for treatments against autoimmune diseases like ... tissues. The findings, reported by scientists who performed the ...
... Forest Service Southern Research Station (SRS) scientists and partners ... faster than expected in the southern Appalachians and rapidly ... and cooperators from the University of Georgia published the ... Ecosystems . "The study marks the ...
... has found that modern lifestyle habits may play a bigger ... A review of the scientific evidence over the ... good oral hygiene and health education, may override the effects ... online in a Supplement to the journal Obesity Reviews ...
Cached Biology News:A worm-and-mouse tale: B cells deserve more respect 2A worm-and-mouse tale: B cells deserve more respect 3Study finds hemlock trees dying rapidly, affecting forest carbon cycle 2
(Date:1/15/2014)... Toronto, ON (PRWEB) January 15, 2014 ... an experimental new therapy for the treatment of tinnitus. ... unique tinnitus frequency, and over a period of weeks to ... Notched Sound Therapy in two forms: Notched Music and Notched ...
(Date:1/14/2014)... CA (PRWEB) January 14, 2014 Histogen, ... the products of cells grown under simulated embryonic conditions, ... license agreement with Suneva Medical, Inc. for physician-dispensed aesthetic ... , This agreement is an amendment to ...
(Date:1/14/2014)... Texas , Jan. 14, 2014 The ... and research medicinal plants and therapeutic derivatives thereof ... health professionals, and researchers about the challenges of ... http://photos.prnewswire.com/prnh/20100430/DC95601LOGO ) The Society ...
(Date:1/14/2014)... , Jan. 14, 2014  RXi Pharmaceuticals Corporation (OTCQX: ... and commercializing innovative therapies addressing major unmet medical ... received the Notice of Allowance from the United ... self-delivering RNAi compounds (sd-rxRNA®), for the treatment of ...
Breaking Biology Technology:Histogen and Suneva Medical Expand License for Cell Conditioned Media-based Aesthetic Products Internationally 2Histogen and Suneva Medical Expand License for Cell Conditioned Media-based Aesthetic Products Internationally 3World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 2World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 3World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 4World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 5World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 6World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 7World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 8RXi Pharmaceuticals Receives US Notice of Allowance for a Key Patent Relating to its Self-Delivering Technology with sd-rxRNAs targeting CTGF, including RXI-109, for the Treatment of Fibrotic Disorders 2RXi Pharmaceuticals Receives US Notice of Allowance for a Key Patent Relating to its Self-Delivering Technology with sd-rxRNAs targeting CTGF, including RXI-109, for the Treatment of Fibrotic Disorders 3
... Mich., May 3, 2011 Adeona Pharmaceuticals, Inc. (AMEX: ... for serious central nervous system diseases, announced today that ... Trimesta™ (oral estriol) drug candidate for multiple sclerosis (MS) ... the National Institutes of Health/National Institute of Neurological Disorders ...
... Inc. (NYSE: LDR ), a recognized global ... domestic provider of outsourced medical physics services, today reported financial ...   Fiscal 2011 Second Quarter Highlights ... contribution from Medical Physics segment and international growth. Gross ...
... Verenium Corporation (NASDAQ: VRNM ), a pioneer ... today announced that Jeff Black, Senior Vice President and Chief ... Bright Lights Conference.  The presentation is scheduled to begin at ... take place at the Le Parker Meridien Hotel in New ...
Cached Biology Technology:Adeona's Multiple Sclerosis Clinical Trial Receives $1,594,553 Grant 2Adeona's Multiple Sclerosis Clinical Trial Receives $1,594,553 Grant 3Adeona's Multiple Sclerosis Clinical Trial Receives $1,594,553 Grant 4Landauer, Inc. Reports Fiscal 2011 Second Quarter Results 2Landauer, Inc. Reports Fiscal 2011 Second Quarter Results 3Landauer, Inc. Reports Fiscal 2011 Second Quarter Results 4Landauer, Inc. Reports Fiscal 2011 Second Quarter Results 5Landauer, Inc. Reports Fiscal 2011 Second Quarter Results 6Landauer, Inc. Reports Fiscal 2011 Second Quarter Results 7Landauer, Inc. Reports Fiscal 2011 Second Quarter Results 8Landauer, Inc. Reports Fiscal 2011 Second Quarter Results 9Landauer, Inc. Reports Fiscal 2011 Second Quarter Results 10Landauer, Inc. Reports Fiscal 2011 Second Quarter Results 11Landauer, Inc. Reports Fiscal 2011 Second Quarter Results 12Verenium to Present at MDB Capital Group's Bright Lights Conference 2Verenium to Present at MDB Capital Group's Bright Lights Conference 3
... The mycobacteria in Complete Freund's adjuvant attract ... site which enhances the immuneresponse. For this ... for the initial injections; Incomplete Freund's adjuvant ... (preferably in saline) are typically mixed with ...
The ELISA Kit for Hepatitis B Surface Antigen (HBsAg) is an in vitro enzyme immunoassay for the detection of HBsAg in human serum or plasma....
2,4-Dinitrophenyl hapten is conjugated to Keyhole Limpet (KLH) protein through lysine....
Alexa Fluor 350/488/594 Filter Set (Semrock Brightline) *mounted* *Zeiss Axio AF...
Biology Products: