From the simple to the complex
The key breakthrough came when he realized that the ribosome is organized by a set of simple structural rules and that it had to be assembled from basic building blocks in a very specific order; otherwise it would have fallen apart. He then showed with mathematical rigor that the construction of the ribosome likely followed an ordered series of steps to form the structure found in the first living cell. To this day, that structure exists almost unchanged in our own cells.
Chemists have been able to observe many examples of self-organizing behavior with simple molecules, yet explaining the complex self-assembly of biomolecules had not been so obvious.
"Thanks to the research of Sergey Steinberg and Konstantin Bokov, scientists now have a glimpse of one key event that emerged spontaneously out of the primordial chemical soup of the early Earth," explains Stephen Michnick, a Universit de Montral biochemistry professor and Canada Research Chair in Integrative Genomics. "Perhaps in the near future we may look forward to more discoveries that will take us beyond the world of Darwin into an understanding of the basic chemical principles that drove the emergence of life on our planet and perhaps beyond."
|Contact: Sylvain-Jacques Desjardins|
University of Montreal