Navigation Links
Life-saving in the bacterial world: How Campylobacter rely on Pseudomonas to infect humans
Date:10/7/2010

Many a holiday is ruined by food poisoning, frequently caused by the bacterium Campylobacter jejuni. Although Campylobacter infections are rarely life-threatening they are extremely debilitating and have been linked with the development of Guillain-Barr syndrome, one of the leading causes of non-trauma-induced paralysis worldwide.

Campylobacter jejuni is well adapted to life in the guts of animals and birds, where it is often found in very high levels. However, to infect humans it also needs to be able to survive outside the gut, on the surface of meat that will be eaten by humans. It is known that C. jejuni cannot grow under normal atmospheric conditions the levels of oxygen are too high for it so how it survives was until recently unknown. The mystery has now been solved by Friederike Hilbert and colleagues at the Institute of Meat Hygiene, Meat Technology and Food Science of the University of Veterinary Medicine, Vienna.

The surface of meat harbours a number of species of bacteria that fortunately are rarely harmful to humans, although they are associated with spoilage. It seems possible that the various species interact and Hilbert hypothesized that such interactions might help bacteria such as Campylobacter jejuni survive under hostile, oxygen-rich conditions. She thus tested the survival of C. jejuni in the presence of various meat-spoiling bacteria. When incubated alone or together with bacteria such as Proteus mirabilis or Enterococcus faecalis, Campylobacter survived atmospheric oxygen levels for no longer than 18 hours. However, when incubated together with various strains of Pseudomonas, Campylobacter were found to survive for much longer, in some cases over 48 hours, which would be easily long enough to cause infection.

There were differences in the extent of prolonged survival depending on the sources of the Campylobacter analysed but all isolates of all strains clearly survived significantly longer in the presence of Pseudomonas bacteria than when cultured alone. And the Campylobacter cells did not change shape when cultured together with Pseudomonas under oxygen-rich conditions, unlike when they were cultured alone, providing further indications of an interaction between the species. Interestingly, there is no evidence that the Pseudomonas benefit at all from the interaction, although they effectively save the lives of the Campylobacter.

Hilbert's findings show clearly that the presence of Pseudomonas bacteria is responsible for significantly enhanced survival of the disease-causing Campylobacter bacteria on the surface of meat. The results have implications for the control of meat, especially poultry, destined for human consumption. As Hilbert says, "On the basis of this study it should be possible to elucidate new mechanisms for limiting the level of Campylobacter on chicken meat and thus the incidence of food poisoning could be much reduced."


'/>"/>

Contact: Prof. Friederike Hilbert
friederike.hilbert@vetmeduni.ac.at
University of Veterinary Medicine -- Vienna
Source:Eurekalert

Related biology news :

1. Study finds life-saving trend among seagulls
2. Gene against bacterial attack unravelled
3. Predatory bacterial swarm uses rippling motion to reach prey
4. Nature study demonstrates that bacterial clotting depends on clustering
5. Shifts in soil bacterial populations linked to wetland restoration success
6. Caltech researchers get first 3-D glimpse of bacterial cell-wall architecture
7. Scientists present moving theory behind bacterial decision-making
8. Scientists build roach motel for nasty bugs of the bacterial variety
9. Bacterial biofilms as fossil makers
10. Winter brings flu, summer brings bacterial infections
11. Computation and genomics data drive bacterial research into new golden age
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/2/2016)... 2, 2016  Based on its recent analysis ... recognizes US-based Intelligent Retinal Imaging Systems (IRIS) with ... for New Product Innovation. IRIS, a prominent cloud-based ... America , is poised to set the ... retinopathy market. The IRIS technology presents superior price-performance ...
(Date:1/27/2016)... CHESTER, Ohio , Jan. 27, 2016  Rite ... supplier based in West Chester, Ohio ... their award winning service staff, based in ... technical capacity and ability to provide modifications, installations and ... John Dovalina , CEO of PLUS, commented, "PLUS has ...
(Date:1/21/2016)... 21, 2016 --> ... market research report "Emotion Detection and Recognition Market by Technology ... (Facial Expression, Voice Recognition and Others), Services, Application ... to 2020", published by MarketsandMarkets, the global Emotion ... USD 22.65 Billion by 2020, at a CAGR ...
Breaking Biology News(10 mins):
(Date:2/12/2016)... PA (PRWEB) , ... February 12, 2016 , ... ... at the Georgia World Congress Center in Atlanta, Georgia, will include 848 exhibitors ... These leading companies will be displaying products and services used by the scientific ...
(Date:2/11/2016)... NBIX ) today announced its financial results for the quarter ... --> For the fourth quarter of 2015, the ... per share, compared to a net loss of $19.4 million, or ... the year ended December 31, 2015, the Company reported a net ... to a net loss of $60.5 million, or $0.81 loss per ...
(Date:2/11/2016)... ATLANTA , Feb. 11, 2016  Wellcentive ... a Portland, Oregon -based community ... to provide population health analytics, quality reporting and ... help FamilyCare strengthen its team of quality managers, ... reporting to the provider groups serving FamilyCare members. ...
(Date:2/11/2016)... Buffalo, New York (PRWEB) , ... February 11, ... ... and analytical instruments for more than 150 years, continues today to pursue the ... to its line of analytical instruments: the AR9 Refractometer and the AR5 Refractometer. ...
Breaking Biology Technology: