Navigation Links
Licking your wounds: Scientists isolate compound in human saliva that speeds wound healing
Date:7/23/2008

A report by scientists from The Netherlands published online in The FASEB Journal (http://www.fasebj.org) identifies a compound in human saliva that greatly speeds wound healing. This research may offer hope to people suffering from chronic wounds related to diabetes and other disorders, as well as traumatic injuries and burns. In addition, because the compounds can be mass produced, they have the potential to become as common as antibiotic creams and rubbing alcohol.

"We hope our finding is ultimately beneficial for people who suffer from non-healing wounds, such as foot ulcers and diabetic ulcers, as well as for treatment of trauma-induced wounds like burns," said Menno Oudhoff, first author of the report.

Specifically, scientists found that histatin, a small protein in saliva previously only believed to kill bacteria was responsible for the healing. To come to this conclusion, the researchers used epithelial cells that line the inner cheek, and cultured in dishes until the surfaces were completely covered with cells. Then they made an artificial wound in the cell layer in each dish, by scratching a small piece of the cells away. In one dish, cells were bathed in an isotonic fluid without any additions. In the other dish, cells were bathed in human saliva. After 16 hours the scientists noticed that the saliva treated "wound" was almost completely closed. In the dish with the untreated "wound," a substantial part of the "wound" was still open. This proved that human saliva contains a factor which accelerates wound closure of oral cells. Because saliva is a complex liquid with many components, the next step was to identify which component was responsible for wound healing. Using various techniques the researchers split the saliva into its individual components, tested each in their wound model, and finally determined that histatin was responsible.

"This study not only answers the biological
'/>"/>

Contact: Cody Mooneyhan
cmooneyhan@faseb.org
301-634-7104
Federation of American Societies for Experimental Biology
Source:Eurekalert

Page: 1 2

Related biology news :

1. Training future scientists at the Ecological Society of Americas 93rd Annual Meeting
2. Gladstone scientists create Wikipathways to foster research collaboration
3. Nature publishes new evidence about the deep biosphere written by biogeoscientists
4. ASBMB taps 8 scientists for top awards
5. When fish talk, scientists listen
6. Scientists demonstrate the sharpest measurement of ice crystals in clouds
7. Scientists demonstrate means of reducing Alzheimers-like plaques in fly brain
8. Scientists discover key patterns in the packaging of genes
9. Scripps research scientists reveal key structure from ebola virus
10. Scientists learn how food affects the brain
11. Scientists discover new reefs teeming with marine life in Brazil
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/23/2015)... 2015 SoundView Technology Group issues a new research ... ) Wocket smart wallet. SoundView was one of the selected user ... with the Wocket in multiple scenarios and outlets. ... other retailers, making both debit and credit card payments.  ... "If the company meets their plans in 2015, it would ...
(Date:3/20/2015)... DUBLIN , Mar. 20, 2015 Research ... announced the addition of the "India Sensors ... their offering. The sensor market is ... through 2020 Consumer electronics, automotive, industrial ... for sensors in the country. In addition, adoption ...
(Date:3/19/2015)... March 19, 2015  NXT-ID, Inc. (NASDAQ: NXTD ... on the growing mobile commerce market, announces its biometric payment ... clip that aired this week on Washington DC,s ... In a segment "The Next Great Thing", host ... way to pay, and ,a really big breakthrough in mobile ...
Breaking Biology News(10 mins):Technology Research Note Update from SoundView; Real-World Usage and Feedback of Wocket Smart Wallet at CVS, Whole Foods and other Retailers 2Technology Research Note Update from SoundView; Real-World Usage and Feedback of Wocket Smart Wallet at CVS, Whole Foods and other Retailers 3Technology Research Note Update from SoundView; Real-World Usage and Feedback of Wocket Smart Wallet at CVS, Whole Foods and other Retailers 4India Sensors Market Forecast and Opportunities 2020 - STMicroelectronics held the largest share in 2014 2India Sensors Market Forecast and Opportunities 2020 - STMicroelectronics held the largest share in 2014 3NXT-ID's Wocket Smart Wallet Featured on Fox News Segment, "The Next Great Thing" 2NXT-ID's Wocket Smart Wallet Featured on Fox News Segment, "The Next Great Thing" 3
... TAMPA, Fla. (Nov. 19, 2012) In three studies published in ... of the National Academy of Inventors , innovators unveil creative ... of energy, and change our lives. Untapped energy in ... and in Florida,s ocean waves can be captured and used, said ...
... has applied for a patent for a genetically-engineered vaccine strategy ... body structures that are the first sites of contact with ... last a lifetime, the vaccine will lead to the continual ... system. Another feature of the vaccine system is that it ...
... with histonesthe proteins that package DNAregulate many fundamental cell activities ... or blood cells becoming leukemic. These interactions are governed by ... chemically modify histones signaling them to clamp down tighter on ... expressed. In the November 19, 2012, online ...
Cached Biology News:New energy technologies promise brighter future 2New energy technologies promise brighter future 3Texas Biomed files patent for a novel HIV vaccine strategy 2Fruit fly studies guide investigators to misregulated mechanism in human cancers 2Fruit fly studies guide investigators to misregulated mechanism in human cancers 3
(Date:4/23/2015)... CA (PRWEB) April 23, 2015 Athena ... personal development of executive women in San Diego’s technology ... the 17th Annual Pinnacle Awards at their Gala on ... Hyatt Hotel. Register now at http://athenasd.org/events/ , ... support the Athena San Diego vision of fostering networking, ...
(Date:4/23/2015)... , April 23, 2015  Neurocrine Biosciences, Inc. (Nasdaq: ... report its first quarter 2015 results before the Nasdaq ... then host a live conference call and webcast to discuss ... morning, April 30, 2015 at 8:00 a.m. Eastern Time ... the live conference call by dialing 866-952-1906 (US) or ...
(Date:4/23/2015)... Prospects for Leading Companies in ... Details   We predict the global healthcare ... in 2015 and will grow at a CAGR of 6.3% ... around the world and increasing functional requirements for healthcare packaging ... global healthcare packaging market. A global ageing population, ...
(Date:4/23/2015)... April 23, 2015 /PRNewswire/ - Crystal Research Associates, LLC ... Overview ® (EIO) on Aeterna Zentaris Inc. (NASDAQ: ... available on Crystal Research Associates, website at ... website at www.aezsinc.com . Aeterna Zentaris ... biopharmaceutical company in oncology, endocrinology, and women,s health. With ...
Breaking Biology Technology:Athena Pinnacle Awards to Honor Executives, Corporations and Educators Working to Promote Women Leaders 2Neurocrine Biosciences Announces Conference Call and Webcast to Report First Quarter 2015 Results 2Healthcare Packaging Market Forecast 2015-2025 2Healthcare Packaging Market Forecast 2015-2025 3Healthcare Packaging Market Forecast 2015-2025 4Healthcare Packaging Market Forecast 2015-2025 5Healthcare Packaging Market Forecast 2015-2025 6Healthcare Packaging Market Forecast 2015-2025 7Healthcare Packaging Market Forecast 2015-2025 8Healthcare Packaging Market Forecast 2015-2025 9Healthcare Packaging Market Forecast 2015-2025 10Crystal Research Associates, LLC Issues Executive Informational Overview (EIO) on Aeterna Zentaris Inc. 2Crystal Research Associates, LLC Issues Executive Informational Overview (EIO) on Aeterna Zentaris Inc. 3
... Hospital (TSH),Canada,s largest urban community hospital, has selected ... physicians. The,implementation of Chyma(TM) for their team of ... ER departments at the two hospital campuses and ... medicine., "Chyma(TM) reflects the commitment of the ...
... Mass., June 2 RainDance Technologies, Inc.,a ... health and,disease research, today announced the appointment ... effective immediately., "As RainDance solutions enter ... to establish our manufacturing and financial capabilities,",said ...
... announced the,release of a new and exciting module ... experience with different techniques and,alternative approaches to the ... The GYN module is the latest addition to ... Mentor, the world,s most advanced,laparoscopic surgery simulator. The ...
Cached Biology Technology:Canada's Largest Urban Community Hospital Chooses Chyma(TM) On-Call Physician Scheduling Technology 2RainDance Appoints Kelly Chief Operating Officer 2Simbionix Takes Non-Invasive GYN Surgical Training to the Next Level 2
... and Sartolab P20 plus,for Reliable Sterile Filtration ... attached to a,membrane pump or tube pump, ... liter of media,and aqueous solutions. The ... and an automatic de-aeration,ensures high flow rates ...
... a fluorescent microscopy-based imaging system that accurately ... automatically calculates cell viability, in a single ... the variability associated with the subjective interpretation ... the EasyCount ViaSure Kit, up to six ...
... Adept CE 4100 high pressure pump ... precision, with software drive compensation, reducing pulsing ... are selectable in 0.001mL steps. , The ... and bio-compatible., Pumps may be programmed from ...
... filter paper sandwiches are composed of a ... of thick filter paper that are preassembled ... sandwich. These 7 x 8.5 cm membrane ... Ready Gel-sized gels and are supplied as ...
Biology Products: