Navigation Links
Let's get moving: Unraveling how locomotion starts
Date:5/16/2012

While experiments in the 1970s using electrical brain stimulation identified areas of the brain responsible for starting locomotion, the precise neuron-by-neuron pathway has not been described in any vertebrate until now.

To find this pathway, Dr Edgar Buhl and colleagues in Bristol's School of Biological Sciences studied a small, simple vertebrate: the Xenopus frog tadpole.

They found that the pathway to initiate swimming consists of just four types of neurons. By touching skin on the head of the tadpole and applying cellular neurophysiology and anatomy techniques, the scientists identified nerve cells that detect the touch on the skin, two types of brain nerve cells which pass on the signal, and the motor nerve cells that control the swimming muscles.

Dr Buhl said: "These findings address the longstanding question of how locomotion is initiated following sensory stimulation and, for the first time in any vertebrate, define in detail a direct pathway responsible. They could thus be of great evolutionary interest and could also open the path to understanding initiation of locomotion in other vertebrates."

When mechanisms in the brain that initiate locomotion break down for example, in people with Parkinson's disease starting to walk becomes a real problem. Therefore, understanding the initiation of swimming in tadpoles could be a first step towards understanding the initiation of locomotion in more complex vertebrates, including people, and may eventually have implications for treating movement disorders such as Parkinson's.

The research is published today in the Journal of Physiology.


'/>"/>

Contact: Hannah Johnson
hannah.johnson@bristol.ac.uk
44-117-928-8896
University of Bristol
Source:Eurekalert

Page: 1

Related biology news :

1. Providing toilets, safe water is top route to reducing world poverty: UN University
2. Just a little squeeze lets proteins assess DNA
3. Single gene lets bacteria jump from host to host
4. New reference material can improve testing of multivitamin tablets
5. Researchers explore new driver of transplant rejection: Platelets
6. Childrens National research links platelets to sepsis-related organ failure
7. Lipid droplets lead a Spartin existence
8. BIO-key(R) Enters Strategic Partnership With Nlets
9. BIO-key(R) Enters Strategic Partnership With Nlets
10. Green tea component may help preserve stored platelets, tissues
11. New nanochemistry technique encases single molecules in microdroplets
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/11/2017)... BROOKLYN, N.Y. , April 11, 2017 /PRNewswire-USNewswire/ ... identical fingerprints, but researchers at the New York ... University College of Engineering have found that partial ... fingerprint-based security systems used in mobile phones and ... previously thought. The vulnerability lies in ...
(Date:4/5/2017)... 2017 Today HYPR Corp. , leading ... component of the HYPR platform is officially FIDO® ... security architecture that empowers biometric authentication across Fortune 500 ... secured over 15 million users across the financial services ... home product suites and physical access represent a growing ...
(Date:3/30/2017)... -- On April 6-7, 2017, Sequencing.com will host the world,s ... at Microsoft,s headquarters in Redmond, Washington ... health and wellness apps that provide a unique, personalized ... is the first hackathon for personal genomics and the ... the genomics, tech and health industries are sending teams ...
Breaking Biology News(10 mins):
(Date:8/15/2017)... ... August 15, 2017 , ... Kapstone Medical ... years of successes helping medical technology companies and inventors develop and safeguard their latest ... full-service national engineering firm with a portfolio of clients in the United States and ...
(Date:8/15/2017)... (PRWEB) , ... August 15, 2017 , ... ... of the largest Asian exhibitions for analytical and scientific instruments. This year’s symposium, ... be “New Approaches in Mass Spectrometry for Bioanalytical Applications.” This dynamic presentation will ...
(Date:8/15/2017)... ... August 15, 2017 , ... ... 6” modular downlights designed to stay tightly sealed and perform efficiently for years. ... and wet location listings just aren't enough, such as: hospitals; behavioral health facilities; ...
(Date:8/15/2017)... ... August 15, 2017 , ... Coffea arabica accounts for 70 ... factors. During this educational webinar, participants will learn about the importance of genomics ... better understanding of how genomics is important for coffee breeding improvement. , Attendees ...
Breaking Biology Technology: