Navigation Links
Let's get moving: Unraveling how locomotion starts
Date:5/16/2012

While experiments in the 1970s using electrical brain stimulation identified areas of the brain responsible for starting locomotion, the precise neuron-by-neuron pathway has not been described in any vertebrate until now.

To find this pathway, Dr Edgar Buhl and colleagues in Bristol's School of Biological Sciences studied a small, simple vertebrate: the Xenopus frog tadpole.

They found that the pathway to initiate swimming consists of just four types of neurons. By touching skin on the head of the tadpole and applying cellular neurophysiology and anatomy techniques, the scientists identified nerve cells that detect the touch on the skin, two types of brain nerve cells which pass on the signal, and the motor nerve cells that control the swimming muscles.

Dr Buhl said: "These findings address the longstanding question of how locomotion is initiated following sensory stimulation and, for the first time in any vertebrate, define in detail a direct pathway responsible. They could thus be of great evolutionary interest and could also open the path to understanding initiation of locomotion in other vertebrates."

When mechanisms in the brain that initiate locomotion break down for example, in people with Parkinson's disease starting to walk becomes a real problem. Therefore, understanding the initiation of swimming in tadpoles could be a first step towards understanding the initiation of locomotion in more complex vertebrates, including people, and may eventually have implications for treating movement disorders such as Parkinson's.

The research is published today in the Journal of Physiology.


'/>"/>

Contact: Hannah Johnson
hannah.johnson@bristol.ac.uk
44-117-928-8896
University of Bristol
Source:Eurekalert

Page: 1

Related biology news :

1. Providing toilets, safe water is top route to reducing world poverty: UN University
2. Just a little squeeze lets proteins assess DNA
3. Single gene lets bacteria jump from host to host
4. New reference material can improve testing of multivitamin tablets
5. Researchers explore new driver of transplant rejection: Platelets
6. Childrens National research links platelets to sepsis-related organ failure
7. Lipid droplets lead a Spartin existence
8. BIO-key(R) Enters Strategic Partnership With Nlets
9. BIO-key(R) Enters Strategic Partnership With Nlets
10. Green tea component may help preserve stored platelets, tissues
11. New nanochemistry technique encases single molecules in microdroplets
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/15/2014)... deforestation could cause temperatures in the Congo Basin ... intensify warming caused by greenhouse gases by half, ... University of Leuven, Belgium. , Explosive population growth ... of tropical rainforests in Central Africa. A team ... how these practices will affect longer-term temperatures in ...
(Date:4/15/2014)... IL (April 15, 2014) New research published ... of the American College of Nutrition shows whey ... or as part of a weight-loss or weight-maintenance diet, ... composition. , The meta-analysis included 14 randomized controlled ... researchers analyzed those weight loss studies that used whey ...
(Date:4/14/2014)... the greenhouse gas methane were found above shale gas ... an important emissions source, according to a study jointly ... have implications for the evaluation of the environmental impacts ... one of only a few to use a so-called ... the air above wells, identified seven individual well pads ...
Breaking Biology News(10 mins):Study: Deforestation could intensify climate change in Congo Basin by half 2New meta-analysis builds on the power of whey protein for improved body composition 2New meta-analysis builds on the power of whey protein for improved body composition 3'Problem wells' source of greenhouse gas at unexpected stage of natural gas production 2
... African Americans known to potentially cause hypertension, found Michael ... in the September issue of Experimental Physiology. Brown is ... of Health Professions. The hormone, aldosterone, influences the ... it can contribute to the development of hypertension because ...
... Enjoying your August vacation? Well, (as they say in the ... has been consistently quiet, sudden, and deadly. Unknowingly, we have ... rock -- you personally are not in any danger. Its ... be an accomplice. Melodrama aside, the threat is very ...
... For years, scientists have known that some people are biologically ... only been able to speculate why. In the August ... the University of Chicago report on a study that may ... rats most likely to self-administer addictive drugs had a particular ...
Cached Biology News:Understanding hypertension in African Americans proves elusive 2Humans fostering forest-destroying disease 2Humans fostering forest-destroying disease 3Humans fostering forest-destroying disease 4Nicotinic receptors may be important targets for treatment of multiple addictions 2
(Date:1/15/2014)... January 15, 2014 This webinar ... on nonclinical and clinical safety assessment in biosimilars. ... guide a path for biosimilar drug development, however ... of biosimilarity with regards to quality, safety and ... of biosimilar drug development and registration, development strategies ...
(Date:1/15/2014)... NC (PRWEB) January 15, 2014 ... an enhancement to its Online Web Portal for Life ... now have the ability to specify the subject matter ... nearly 50 life science sub-domains. This will help reduce ... and scientific fields, and decrease the likelihood of error. ...
(Date:1/14/2014)... Doylestown, PA (PRWEB) January 14, 2014 ... – 11 p.m. , Location: Warrington Country Club, 1360 ... Hepatitis B Foundation, the only national nonprofit organization solely ... improving the quality of life for those affected worldwide, ... 11 at Warrington Country Club in Warrington, Pa. ...
(Date:1/14/2014)... York, NY (PRWEB) January 14, 2014 ... initiated coverage of Alliqua, Inc. (OTCQB: ALQA). Alliqua ... and marketing proprietary products to serve the wound ... , In late 2012, Alliqua was restructured ... launched the company’s new strategy to become a ...
Breaking Biology Technology:Xtalks Life Sciences Webinar Examines Safety Assessment of Biosimilars 2DTS Improves Efficiency for Life Science Document Translations 2Hepatitis B Foundation to Host Annual Crystal Ball Gala 2EquitiesIQ Initiates Coverage of Alliqua, Inc. 2EquitiesIQ Initiates Coverage of Alliqua, Inc. 3
... ... its technology platform to support large projects. , ... (PRWEB) January 21, 2010 -- Firmex, the leader in ... to its technology platform. , , , , ,Firmex has released a new architecture ...
... ... development capacity drives PCT to open new facility , ... Allendale, NJ (Vocus) January 22, 2010 -- Progenitor Cell Therapy, LLC ... , , , , ,The company’s new cell therapy development and manufacturing ...
... ... SINGAPORE , January 22 , ... Together for Honors , Elsevier announced today the winners ... Scopus(R), the,world,s largest abstract and citation database of peer-reviewed literature,and the Third World ...
Cached Biology Technology:Firmex Announces Virtual Data Room Enhancements for Large Projects 2Firmex Announces Virtual Data Room Enhancements for Large Projects 3Progenitor Cell Therapy Expands Manufacturing Operations 2Progenitor Cell Therapy Expands Manufacturing Operations 3Scopus(R), TWOWS and TWAS Announce Young Women Researcher Award Recipients in Asia 2Scopus(R), TWOWS and TWAS Announce Young Women Researcher Award Recipients in Asia 3Scopus(R), TWOWS and TWAS Announce Young Women Researcher Award Recipients in Asia 4Scopus(R), TWOWS and TWAS Announce Young Women Researcher Award Recipients in Asia 5Scopus(R), TWOWS and TWAS Announce Young Women Researcher Award Recipients in Asia 6Scopus(R), TWOWS and TWAS Announce Young Women Researcher Award Recipients in Asia 7
... Combining linear motor and ballscrew ... pre-engineered Cartesian solutions that include ... management, and motors., , ... Pass through high-flex cabling for ...
UGT1A6 (D-20)...
... T Squareds patented high efficiency dynamic valve ... With the most compact, lightweight package in ... use in portable air and gas applications., ... high efficiency. , Includes DC Motor. ...
... designed for moving loads quickly and accurately. ... output while limiting overall size. The P5S-P ... ball bearings guided on two rails., ... provide energy absorption and controlled deceleration , ...
Biology Products: