Navigation Links
Lethal stings from the Australian box jellyfish could be treated with zinc
Date:12/12/2012

Box jellyfish of the Chironex species are among the most venomous animals in the world, capable of killing humans with their sting. Their venom, though, which kills by rapidly punching holes in human red blood cells, can be slowed down by administering zinc, according to research published December 12 in the open access journal PLOS ONE by Angel Yanagihara from the University of Hawaii and colleagues.

The researchers developed ways to extract venom from the jellyfish, and tested it on human blood and on mice. They found that the venom created pores in human red blood cells, making them leak large amounts of potassium, which causes cardiac arrest and death.

As Yanagihara elaborates, "For over 60 years researchers have sought to understand the horrifying speed and potency of the venom of the Australian box jellyfish, arguably the most venomous animal in the world. We have found that a previously disregarded hemolysin can cause an avalanche of reactions in cells. This includes an almost instantaneous, massive release of potassium that can cause acute cardiovascular collapse and death."

The authors treated the cells with a zinc compound which inhibits this process, and found that the treatment could slow the pore-forming process in cells, and increased survival times in the mice treated with the compound, zinc gluconate. The research suggests that the venom's capacity to increase potassium levels is what makes it so dangerous, and that rapid administration of zinc may be a potential life-saver in human sting victims.


'/>"/>

Contact: Jyoti Madhusoodanan
jmadhusoodanan@plos.org
415-568-4545
Public Library of Science
Source:Eurekalert  

Page: 1

Related biology news :

1. Ozone treated water v. lethal microbial material
2. Eyeless Australian fish have closest relatives in Madagascar
3. Millipede family added to Australian fauna
4. Australian shipping emissions identified
5. Hunt for superbugs in Australian animals
6. Northrop Grumman Delivers Australian Automated Biometric Information System Trial Proof of Concept
7. Jellyfish on the rise: UBC study
8. Medusa reimagined: Caltech-led team reverse engineers a jellyfish with the ability to swim
9. Artificial jellyfish swims in a heartbeat
10. Heart-powered pacemaker could one day eliminate battery-replacement surgery
11. New test could help track down and prosecute terrorists
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Lethal stings from the Australian box jellyfish could be treated with zinc
(Date:6/20/2016)... DALLAS , June 20, 2016 ... criminal justice technology solutions for public safety, investigation, ... by the prisons involved, it has secured the ... Corrections (DOC) facilities for Managed Access Systems (MAS) ... (4) additional facilities to be installed by October, ...
(Date:6/9/2016)... attendance control systems is proud to announce the introduction of fingerprint attendance control software, ... employees are actually signing in, and to even control the opening of doors. ... ... ... Photo - http://photos.prnewswire.com/prnh/20160609/377487 ...
(Date:6/3/2016)... 2016 Das DOTM ... Nepal hat ein 44 Millionen ... Kennzeichen, einschließlich Personalisierung, Registrierung und IT-Infrastruktur, an ... und Implementierung von Identitätsmanagementlösungen. Zahlreiche renommierte internationale ... teilgenommen, aber Decatur wurde als konformste und ...
Breaking Biology News(10 mins):
(Date:6/27/2016)... , June 27, 2016  Global demand for ... percent through 2020 to $7.2 billion.  This market ... beverages, cleaning products, biofuel production, animal feed, and ... diagnostics, and biocatalysts). Food and beverages will remain ... by increasing consumption of products containing enzymes in ...
(Date:6/27/2016)... ... 2016 , ... Newly created 4Sight Medical Solutions ... healthcare market. The company's primary focus is on new product introductions, to include ... are necessary to help companies efficiently bring their products to market. , The ...
(Date:6/24/2016)... 2016 Epic Sciences unveiled a liquid ... to PARP inhibitors by targeting homologous recombination deficiency ... new test has already been incorporated into numerous ... types. Over 230 clinical trials are ... including PARP, ATM, ATR, DNA-PK and WEE-1. Drugs ...
(Date:6/23/2016)... 2016   Boston Biomedical , an industry ... to target cancer stemness pathways, announced that its ... Drug Designation from the U.S. Food and Drug ... including gastroesophageal junction (GEJ) cancer. Napabucasin is an ... cancer stemness pathways by targeting STAT3, and is ...
Breaking Biology Technology: