Navigation Links
Lethal stings from the Australian box jellyfish could be treated with zinc
Date:12/12/2012

Box jellyfish of the Chironex species are among the most venomous animals in the world, capable of killing humans with their sting. Their venom, though, which kills by rapidly punching holes in human red blood cells, can be slowed down by administering zinc, according to research published December 12 in the open access journal PLOS ONE by Angel Yanagihara from the University of Hawaii and colleagues.

The researchers developed ways to extract venom from the jellyfish, and tested it on human blood and on mice. They found that the venom created pores in human red blood cells, making them leak large amounts of potassium, which causes cardiac arrest and death.

As Yanagihara elaborates, "For over 60 years researchers have sought to understand the horrifying speed and potency of the venom of the Australian box jellyfish, arguably the most venomous animal in the world. We have found that a previously disregarded hemolysin can cause an avalanche of reactions in cells. This includes an almost instantaneous, massive release of potassium that can cause acute cardiovascular collapse and death."

The authors treated the cells with a zinc compound which inhibits this process, and found that the treatment could slow the pore-forming process in cells, and increased survival times in the mice treated with the compound, zinc gluconate. The research suggests that the venom's capacity to increase potassium levels is what makes it so dangerous, and that rapid administration of zinc may be a potential life-saver in human sting victims.


'/>"/>

Contact: Jyoti Madhusoodanan
jmadhusoodanan@plos.org
415-568-4545
Public Library of Science
Source:Eurekalert  

Page: 1

Related biology news :

1. Ozone treated water v. lethal microbial material
2. Eyeless Australian fish have closest relatives in Madagascar
3. Millipede family added to Australian fauna
4. Australian shipping emissions identified
5. Hunt for superbugs in Australian animals
6. Northrop Grumman Delivers Australian Automated Biometric Information System Trial Proof of Concept
7. Jellyfish on the rise: UBC study
8. Medusa reimagined: Caltech-led team reverse engineers a jellyfish with the ability to swim
9. Artificial jellyfish swims in a heartbeat
10. Heart-powered pacemaker could one day eliminate battery-replacement surgery
11. New test could help track down and prosecute terrorists
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Lethal stings from the Australian box jellyfish could be treated with zinc
(Date:4/6/2017)... Forecasts by Product Type (EAC), ... End-Use (Transportation & Logistics, Government & Public Sector, Utilities ... Generation Facility, Nuclear Power), Industrial, Retail, Business Organisation (BFSI), ... you looking for a definitive report on the $27.9bn ... ...
(Date:4/3/2017)... 2017  Data captured by IsoCode, IsoPlexis ... a statistically significant association between the potency ... and objective response of cancer patients post-treatment. ... whether cancer patients will respond to CAR-T ... as to improve both pre-infusion potency testing and ...
(Date:3/28/2017)... PUNE, India , March 28, 2017 ... (Analog, IP, Biometrics), Hardware (Camera, Monitors, Servers, Storage Devices), ... Maintenance), Vertical, and Region - Global Forecast to 2022", ... 30.37 Billion in 2016 and is projected to reach ... 15.4% between 2017 and 2022. The base year considered ...
Breaking Biology News(10 mins):
(Date:10/11/2017)... Oct. 11, 2017  VMS BioMarketing, a leading provider of ... oncology Clinical Nurse Educator (CNE) network, which will launch this ... communication among health care professionals to enhance the patient care ... staff, and other health care professionals to help women who ... ...
(Date:10/11/2017)... ... 11, 2017 , ... Singh Biotechnology today announced that the ... its novel anti-STAT3 (Signal Transducer and Activator of Transcription 3) B VHH13 single ... the cell membrane and bind intracellular STAT3 and inhibit its function. Dysregulation of ...
(Date:10/10/2017)... ... October 10, 2017 , ... Dr. Bob Harman, founder ... local San Diego Rotary Club. The event entitled “Stem Cells and ... had 300+ attendees. Dr. Harman, DVM, MPVM was joined by two human doctors: ...
(Date:10/10/2017)... ... October 10, 2017 , ... The Pittcon Program Committee ... honoring scientists who have made outstanding contributions to analytical chemistry and applied ... the world’s leading conference and exposition for laboratory science, which will be held ...
Breaking Biology Technology: