Born in 1967, Brigitte Rder studied psychology in Marburg, where she wrote her doctorate in cognitive neuroscience with Frank Rsler and habilitated in 2002. She has spent several periods away from her research home, for example carrying out doctoral and postdoctoral research in Illinois and Oregon. In 1999 she became one of the first funding recipients in the DFG's Emmy Noether Programme. From Marburg she moved to the University of Hamburg, where she continues to teach and research despite receiving several offers from other institutions. She has already received a number of awards, including an ERC Advanced Grant in 2010.
Prof. Dr. Irmgard Sinning (53), Structural Biology, University of Heidelberg
Combining biochemistry, biophysics and structural biology, Irmgard Sinning works at the forefront of research. She is primarily concerned with protein complexes, which transport different membrane proteins to the correct cellular compartments in the appropriate target membranes. The crucial question is how the proteins are transported by the biological membranes. Sinning has published extensively in this area, seeking to explain one of the most important transport mechanisms: transport mediated by the signal recognition particle (SRP). This particle, a complex consisting of protein and ribonucleic acids, first recognises the proteins and binds them to the ribosomes while they are still being formed. The target protein is then transported to a receptor in which a pore opens to allow the protein to be threaded through and "translocated" from one compartment to the next. It is extremely important to understand this process because a membrane protein can only perform its biological function if in the right place and at the right time.
|Contact: Marco Finetti|